Patents by Inventor Karl J. Sanford
Karl J. Sanford has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Patent number: 8901262Abstract: This invention relates to compositions and methods for producing polymers of isoprene derived from renewable resources, such as isoprene produced from cultured cells that use renewable carbon sources. A starting isoprene composition, such as a bioisoprene composition, is distinguished from petroleum based isoprene by its purity profile (such as lower levels of certain C5 hydrocarbons other than isoprene, presence of certain compounds associated with the biological process for production) and the relative content of the carbon isotopes. Polymers obtained by polymerization of such starting isoprene composition according to this invention, such as a polyisoprene homopolymer or a copolymer having repeat units that are derived from isoprene, are distinguishable from isoprene containing polymers from petrochemical resources.Type: GrantFiled: August 20, 2013Date of Patent: December 2, 2014Assignees: The Goodyear Tire & Rubber Company, Danisco US Inc.Inventors: Joseph C. McAuliffe, Sergey Paramonov, Stephan Rodewald, Karl J. Sanford
-
Patent number: 8895288Abstract: The invention features methods producing isoprene and a co-product, such as ethanol, 1,3-propanediol, or hydrogen from cultured cells. The invention also provides compositions that include these cultured cells. The invention provides compositions comprising isoprene and ethanol, isoprene and 1,3-propanediol, and isoprene and hydrogen. Additionally, the invention provides methods of co-producing isoprene and ethanol, isoprene and 1,3-propanediol, and isoprene and hydrogen by culturing cells under conditions suitable for co-production of isoprene and ethanol, isoprene and 1,3-propanediol, and isoprene and hydrogen.Type: GrantFiled: December 30, 2009Date of Patent: November 25, 2014Assignees: Danisco US Inc., The Goodyear Tire & Rubber CompanyInventors: Gopal K. Chotani, Caroline M. Peres, Derek H. Wells, Karl J. Sanford, Joseph C. McAuliffe
-
Publication number: 20140234926Abstract: This invention provides for recombinant anaerobic acetogenic bacterial cells having one or more nucleic acids whereby isoprene, mevalonate and/or other industrial bio-products are produced in a substantially oxygen-free culture condition using synthesis gas as energy and/or carbon source.Type: ApplicationFiled: November 27, 2013Publication date: August 21, 2014Applicants: E I Du Pont De Nemours And Company, The Goodyear Tire And Rubber Company, Danisco US IncInventors: ZACHARY Q. BECK, Marguerite A. Cervin, Gopal K. Chotani, Bruce A. Diner, Janine Fan, Caroline M. Peres, Karl J. Sanford, Miles C. Scotcher, Derek H. Wells, Gregory M. Whited
-
Patent number: 8778647Abstract: The invention provides improved methods for the production of isoprene from biological materials using a membrane bioreactor to culture isoprene-producing cells.Type: GrantFiled: December 22, 2010Date of Patent: July 15, 2014Assignees: Danisco US Inc., The Goodyear Tire & Rubber CompanyInventors: Anthony R. Calabria, Gopal K. Chotani, Robin Fong, Alex T. Nielsen, Karl J. Sanford
-
Publication number: 20140155660Abstract: The invention features methods for producing isoprene from cultured cells wherein the cells in the stationary phase. The invention also provides compositions that include these cultured cells and/or increased amount of isoprene. The invention also provides for systems that include a non-flammable concentration of isoprene in the gas phase. Additionally, the invention provides isoprene compositions, such as compositions with increased amount of isoprene or increased purity.Type: ApplicationFiled: May 20, 2013Publication date: June 5, 2014Applicants: The Goodyear Tire & Rubber Company, Danisco US Inc.Inventors: Anthony R. Calabria, Marguerite A. Cervin, Gopal K. Chotani, Richard La Duca, Joseph C. McAuliffe, Michael C. Miller, Timothy A. Sabo, Karl J. Sanford, Erin L. Spring, Gregory M. Whited
-
Publication number: 20140128645Abstract: The invention provides for methods for the production of isoprene in recombinant marine bacterial cells via the heterologous expression of isoprene synthase enzymes.Type: ApplicationFiled: December 20, 2012Publication date: May 8, 2014Applicants: The Goodyear Tire & Rubber Company, DANISCO US INC.Inventors: Richard LA DUCA, Karl J. SANFORD, Gregory M. WHITED
-
Publication number: 20140127770Abstract: The invention features methods producing isoprene and a co-product, such as ethanol, 1,3-propanediol, or hydrogen from cultured cells. The invention also provides compositions that include these cultured cells. The invention provides compositions comprising isoprene and ethanol, isoprene and 1,3-propanediol, and isoprene and hydrogen. Additionally, the invention provides methods of co-producing isoprene and ethanol, isoprene and 1,3-propanediol, and isoprene and hydrogen by culturing cells under conditions suitable for co-production of isoprene and ethanol, isoprene and 1,3-propanediol, and isoprene and hydrogen.Type: ApplicationFiled: January 6, 2014Publication date: May 8, 2014Applicants: The Goodyear Tire & Rubber Company, Danisco US Inc.Inventors: Gopal K. CHOTANI, Joseph C. MCAULIFFE, Caroline M. PERES, Karl J. SANFORD, Derek H. WELLS
-
Patent number: 8709785Abstract: The invention features methods for producing isoprene from cultured cells. The invention also provides compositions that include these cultured cells.Type: GrantFiled: August 30, 2012Date of Patent: April 29, 2014Assignees: Danisco US Inc., The Goodyear Tire & Rubber CompanyInventors: Marguerite A. Cervin, Gopal K. Chotani, Frank J. Feher, Richard La Duca, Joseph C. McAuliffe, Andrei Miasnikov, Caroline M. Peres, Aaron S. Puhala, Karl J. Sanford, Fernando Valle, Gregory M. Whited
-
Publication number: 20140080983Abstract: This invention relates to compositions and methods for producing polymers of isoprene derived from renewable resources, such as isoprene produced from cultured cells that use renewable carbon sources. A starting isoprene composition, such as a bioisoprene composition, is distinguished from petroleum based isoprene by its purity profile (such as lower levels of certain C5 hydrocarbons other than isoprene, presence of certain compounds associated with the biological process for production) and the relative content of the carbon isotopes. Polymers obtained by polymerization of such starting isoprene composition according to this invention, such as a polyisoprene homopolymer or a copolymer having repeat units that are derived from isoprene, are distinguishable from isoprene containing polymers from petrochemical resources.Type: ApplicationFiled: August 20, 2013Publication date: March 20, 2014Applicants: DANISCO US INC., THE GOODYEAR TIRE & RUBBER COMPANYInventors: Joseph C. McAuliffe, Sergey Paramonov, Stephan Rodewald, Karl J. Sanford
-
Publication number: 20130309743Abstract: The present invention provides methods for producing derivatives from cultured cells. In addition, the present invention provides methods for conversion of prenyl derivatives, obtained from biological or petrochemical sources, to isoprene by employing chemical or biological catalysts. The present invention also provides compositions that include the cultured cells or isoprene or prenyl derivatives produced there from.Type: ApplicationFiled: June 6, 2013Publication date: November 21, 2013Applicants: THE GOODYEAR TIRE & RUBBER COMPANY, DANISCO US INC.Inventors: Joseph C. MCAULIFFE, Samira RATHNAYAKE, Karl J. SANFORD
-
Publication number: 20130280778Abstract: The present invention provides methods for increasing the amount of isoprene produced by cultured cells with only a minimal increase in carbon dioxide emitted, thereby resulting in process having a greater yield of isoprene relative to carbon dioxide. In addition, the present invention provides compositions that include the cultured cells or isoprene produced there from.Type: ApplicationFiled: May 21, 2013Publication date: October 24, 2013Inventors: Gopal K. CHOTANI, Alex T. NIELSEN, Karl J. SANFORD
-
Patent number: 8546506Abstract: The invention features compositions and methods for producing polymers of isoprene derived from renewable resources such as isoprene produced from cultured cells that use renewable carbon sources. A starting isoprene composition, such as a bioisoprene composition, is distinguished from petroleum based isoprene by the purity profile (such as lower levels of certain C5 hydrocarbons other than isoprene, presence of certain compounds associated with the biological process for production) and the relative content of the carbon isotopes. Polymers obtained by polymerization of such starting isoprene composition according to this invention, such as a polyisoprene homopolymer or a copolymer having repeat units that are derived from isoprene, are distinguishable from isoprene containing polymers from petrochemical resources.Type: GrantFiled: June 16, 2010Date of Patent: October 1, 2013Assignees: The Goodyear Tire & Rubber Company, Danisco US Inc.Inventors: Joseph C. McAuliffe, Sergey Paramonov, Stephan Rodewald, Karl J. Sanford
-
Publication number: 20130253141Abstract: It has been found that certain cells in culture can convert more than about 0.002 percent of the carbon available in the cell culture medium into isoprene. These cells have a heterologous nucleic acid that (i) encodes an isoprene synthase polypeptide and (ii) is operably linked to a promoter. The isoprene produced in such a cultured medium can then be recovered and polymerized into synthetic rubbers and other useful polymeric materials. The synthetic isoprene containing polymers of this invention offer the benefit of being verifiable as to being derived from non-petrochemical based resources. They can also be analytically distinguished from rubbers that come from natural sources. The present invention more specifically discloses a polyisoprene polymer which is comprised of repeat units that are derived from isoprene monomer, wherein the polyisoprene polymer has ?13C value of greater than ?22‰.Type: ApplicationFiled: March 11, 2013Publication date: September 26, 2013Applicants: DANISCO US INC., THE GOODYEAR TIRE & RUBBER COMPANYInventors: Frank J. Feher, Gregory M. Whited, Gopal K. Chotani, Fernando Valle, Carol Fioresi, Karl J. Sanford, Joseph McAuliffe, Marguerite Cervin, Aaron S. Puhala, Andrei Miasnikov, Ilana S. Aldor
-
Patent number: 8476049Abstract: The present invention provides methods for producing derivatives from cultured cells. In addition, the present invention provides methods for conversion of prenyl deerivatives, obtained from biological or petrochemical sources, to isoprene by employing chemical or biological catalysts. The present invention also provides compositions that include the cultured cells or isoprene or prenyl derivatives produced there from.Type: GrantFiled: September 15, 2009Date of Patent: July 2, 2013Assignees: Danisco US Inc., The Goodyear Tire & Rubber CompanyInventors: Joseph C. McAuliffe, Samira Rathnayake, Karl J. Sanford
-
Patent number: 8470581Abstract: The present invention provides methods for increasing the amount of isoprene produced by cultured cells with only a minimal increase in carbon dioxide emitted, thereby resulting in process having a greater yield of isoprene relative to carbon dioxide. In addition, the present invention provides compositions that include the cultured cells or isoprene produced there from.Type: GrantFiled: September 15, 2009Date of Patent: June 25, 2013Assignees: Danisco US Inc., The Goodyear Tire & Rubber CompanyInventors: Gopal K. Chotani, Alex Nielsen, Karl J. Sanford
-
Patent number: 8450549Abstract: The invention provides for methods, compositions and systems using bioisoprene derived from renewable carbon for production of a variety of hydrocarbon fuels and fuel additives.Type: GrantFiled: June 17, 2010Date of Patent: May 28, 2013Assignee: Danisco US Inc.Inventors: Joseph C. McAuliffe, Sergey E. Paramonov, Karl J. Sanford
-
Patent number: 8420360Abstract: The invention features methods for producing isoprene from cultured cells wherein the cells in the stationary phase. The invention also provides compositions that include these cultured cells and/or increased amount of isoprene. The invention also provides for systems that include a non-flammable concentration of isoprene in the gas phase. Additionally, the invention provides isoprene compositions, such as compositions with increased amount of isoprene or increased purity.Type: GrantFiled: July 1, 2009Date of Patent: April 16, 2013Assignees: Danisco US Inc., The Goodyear Tire & Rubber CompanyInventors: Anthony R. Calabria, Marguerite A. Cervin, Gopal K. Chotani, Richard La Duca, Joseph C. McAuliffe, Michael C. Miller, Timothy A. Sabo, Karl J. Sanford, Erin L. Webster, Gregory M. Whited
-
Patent number: 8420759Abstract: It has been found that certain cells in culture can convert more than about 0.002 percent of the carbon available in the cell culture medium into isoprene. These cells have a heterologous nucleic acid that (i) encodes an isoprene synthase polypeptide and (ii) is operably linked to a promoter. The isoprene produced in such a cultured medium can then be recovered and polymerized into synthetic rubbers and other useful polymeric materials. The synthetic isoprene containing polymers of this invention offer the benefit of being verifiable as to being derived from non-petrochemical based resources. They can also be analytically distinguished from rubbers that come from natural sources. The present invention more specifically discloses a polyisoprene polymer which is comprised of repeat units that are derived from isoprene monomer, wherein the polyisoprene polymer has ?13C value of greater than ?22‰.Type: GrantFiled: June 30, 2009Date of Patent: April 16, 2013Assignees: The Goodyear Tire & Rubber Company, Danisco US, Inc.Inventors: Frank J. Feher, Gregory M. Whited, Gopal K. Chotani, Fernando Valle, Carol Fioresi, Karl J. Sanford, Joseph C. McAuliffe, Marguerite Cervin, Aaron S. Puhala, Andrei Miasnikov, Ilana S. Aldor
-
Publication number: 20130078699Abstract: The invention features methods for producing isoprene from cultured cells. The invention also provides compositions that include these cultured cells.Type: ApplicationFiled: August 30, 2012Publication date: March 28, 2013Applicants: The Goodyear Tire & Rubber Company, Danisco US Inc.Inventors: Marguerite A. CERVIN, Gopal K. Chotani, Frank J. Feher, Richard La Duca, Joseph C. McAuliffe, Andrei Miasnikov, Caroline M. Peres, Aaron S. Puhala, Karl J. Sanford, Fernando Valle, Gregory M. Whited
-
Publication number: 20130071908Abstract: The invention features methods for producing isoprene from cultured cells. The invention also provides compositions that include these cultured cells.Type: ApplicationFiled: August 30, 2012Publication date: March 21, 2013Applicants: The Goodyear Tire & Rubber Company, Danisco US Inc.Inventors: Marguerite A. CERVIN, Gregory M. Whited, Gopal K. Chotani, Fernando Valle, Karl J. Sanford, Joseph C. McAuliffe, Frank J. Feher, Aaron S. Puhala, Andrei Miasnikov, Richard La Duca, Caroline M. Peres