Patents by Inventor Karl KEATING
Karl KEATING has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240180571Abstract: A clot removal assembly for removing a clot from a vessel that includes a delivery catheter, a clot retrieval device, and a valve assembly is presented herein. In some examples, the clot retrieval device can include a cage structure and a shaft, and the cage structure can be configured to pinch a clot. A portion of the shaft extends through the delivery catheter. In some examples, the valve assembly can include a distal valve, a main body portion, a distal body portion, and a moveable head shell. The distal valve can be configured to engage the proximal region of the delivery catheter. In some examples, the distal body portion can include a plurality of grooves, and the moveable head can be configured to ratchet proximally over the plurality of grooves to thereby maintain tension on the shaft.Type: ApplicationFiled: December 1, 2022Publication date: June 6, 2024Applicant: Neuravi LimitedInventors: Anushree DWIVEDI, Sarah JOHNSON, Declan LEE, Karl KEATING
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Patent number: 11969180Abstract: Devices described herein include an actuated clot retrieval catheter system. The system includes a catheter having a frame disposed proximate the distal end of the catheter. The frame expands to form a seal with the inner wall of a vessel. In some examples, the frame also captures a clot for removal from the vessel. The frame is manufactured from a shape memory material that can be heat set into a predetermined shape. An electrical connection to an electronic circuit causes a current to run through the frame. The electrical resistance of the shape memory material causes the frame to heat and transition from a martensite to an austenite phase. When the frame is heat set into an expanded configuration, the current causes the frame heat and expand. When the frame is heat set into a closed configuration, the current causes the frame heat and collapse upon a clot.Type: GrantFiled: April 14, 2022Date of Patent: April 30, 2024Assignee: NEURAVI LIMITEDInventors: Ronald Kelly, Karl Keating
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Patent number: 11957855Abstract: A balloon guide catheter including a catheter shaft having a main lumen defined therein extending axially therethrough to receive a guidewire therein and an inflation lumen defined axially therein arranged semi-encircling the main lumen. The inflation lumen having an inlet port radially outward from the catheter shaft and an exhaust vent(s) disposed proximate the distal end of the catheter shaft. The exhaust vent(s) being disposed longitudinally through a distal terminating end of the inflation lumen or radially inward in fluid communication with the main lumen. A porous membrane is disposed at the exhaust vent(s) to permit only gas to pass therethrough. Secured about the outer surface proximate the distal end of the catheter shaft and coinciding with the inlet port is a balloon.Type: GrantFiled: October 14, 2019Date of Patent: April 16, 2024Assignee: NEURAVI LIMITEDInventors: Brendan Casey, Karl Keating, Ronald Kelly
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Publication number: 20240108854Abstract: An aspiration catheter having a braid formed from a continuous braiding process and having a braided distal tip design with braid terminations joining strand ends is presented herein. The braid terminations can include sleeves, bands, crimps, or other types of connectors that secure pairs ends of oppositely-wound strands to each other at a distal circumference of the braid. The braid terminations can include radiopaque material to help visualize the distal end of the catheter during a procedure.Type: ApplicationFiled: September 29, 2022Publication date: April 4, 2024Applicant: Neuravi LimitedInventors: Karl KEATING, Paulo RATOLA
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Patent number: 11944327Abstract: A system has an outer catheter and an inner aspirating clot retrieval catheter having an expansile distal tip for flow restriction, improved aspiration efficiency, and a large mouth into which a clot or other obstructions can be retrieved. The clot retrieval catheter can have a support tube proximal of the tip. The expansile tip can be a strut framework, and a flexible, low-modulus cover is disposed around at least a portion of the tip strut framework and the proximal support tube. The distal end of the tip can be encapsulated by a low-friction elastomeric lip for atraumatic contact with the walls of a blood vessel. The tip has a collapsed delivery configuration and expands radially into a deployed configuration. The tip strut framework, support tube, and cover can all have characteristics which enhance the deliverability of the clot retrieval catheter to the target.Type: GrantFiled: March 5, 2020Date of Patent: April 2, 2024Assignee: NEURAVI LIMITEDInventors: David Vale, Ronald Kelly, Brendan Casey, Karl Keating
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Publication number: 20240100298Abstract: A clot retrieval catheter may have a tailored, highly flexible body section capable of navigating tortuous routes and an expandable tip for local flow restriction/arrest. The catheter may contain one or more spines extending the length of the elongate shaft which may be interwoven with the shaft braid. The distal portion of the spine may be formed into a spine hoop as part of the distal hoops of the tip section. Alternatively, the spine may form a loop around the shaft braid. Spines can be made from metal, polymer, or fiber strands. Polymer spines can be formed using a lamination or coextrusion manufacturing method. The support tube can also have a polymer jacket or membrane disposed around at least a portion of the structure.Type: ApplicationFiled: September 26, 2022Publication date: March 28, 2024Applicant: Neuravi LimitedInventors: Karl KEATING, David VALE
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Publication number: 20240066264Abstract: The systems and devices disclosed herein are for a catheter tip that includes a support frame. The support frame can include a longitudinal axis, a collapsed delivery configuration, and an expanded deployed configuration. The support frame can include a collapsed inner diameter in the collapsed delivery configuration and a larger expanded inner diameter in the expanded deployed configuration when the support frame is placed in axial compression. In some examples, the support frame can include one or more profiled spine members extending along the longitudinal axis and a plurality of ribs extending from the one or more profiled spine members. In some examples, the support frame can include a connector rib and a plurality of offset ribs extending from the connector rib. One or more connector members can connect respective ribs of the offset ribs. In some examples, the support frame can include struts forming a lattice structure.Type: ApplicationFiled: August 25, 2022Publication date: February 29, 2024Applicant: Neuravi LimitedInventor: Karl KEATING
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Publication number: 20230414232Abstract: The systems and devices disclosed herein are for a clot retrieval catheter tip that can include a support frame that includes a longitudinal axis, a collapsed configuration, an expanded deployed configuration, and a plurality of interconnected struts. The plurality of interconnected struts can define an axial series of expansion cells and can be joined at opposing pairs of x-connectors spaced 180 degrees apart about the longitudinal axis. Each opposing pair of x-connectors can be rotated 90 degrees about the longitudinal axis with respect to an adjacent opposing pair of x-connectors. The support frame can further include a collapsed inner diameter in the collapsed delivery configuration and a larger expanded inner diameter in the expanded deployed configuration when the support frame is placed in compression.Type: ApplicationFiled: June 24, 2022Publication date: December 28, 2023Applicant: Neuravi LimitedInventors: Karl KEATING, David VALE
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Publication number: 20230414235Abstract: A clot retrieval catheter can have an expansile distal tip for flow restriction/arrest and improved aspiration efficiency and a large, distal facing mouth into which clots or other obstructions can be retrieved. The tip can be formed from a distal ring of leaflets or hoops. One or more pull cables can be retracted to actuate and radially expand the expansile distal tip. The clot retrieval catheter can have a catheter shaft with flexibility-adding features proximal of the tip. The catheter shaft can be a multi-lumen configuration with a large catheter lumen for passing auxiliary devices and directing aspiration and one or more guide lumens which can route the pull cables to the leaflets or hoops of the expansile tip. A flexible, low-modulus membrane can be disposed around at least a portion of the expansile tip and catheter shaft.Type: ApplicationFiled: August 30, 2023Publication date: December 28, 2023Applicant: Neuravi LimitedInventors: Brendan CASEY, Karl KEATING, Ronald KELLY, David VALE
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Publication number: 20230404607Abstract: According to the present disclosure, there is provided a device which can have a funnel catheter having an expandable distal tip. The funnel catheter can originally be placed in a collapsed configuration for delivery through vasculature to a target thrombus location. Once positioned, the expandable tip can be radially expanded to create a funnel for aspirating or retrieving clots from a vessel. The funnel catheter can be at least partially enclosed by an outer sheath for purposes of delivery to the target site or to assist in expansion of the funnel catheter tip.Type: ApplicationFiled: August 31, 2023Publication date: December 21, 2023Applicant: Neuravi LimitedInventors: Ronald KELLY, Karl KEATING
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Patent number: 11839725Abstract: A device for retrieving an obstruction in a blood vessel can have an outer sheath with a distal end, a proximal end, a proximal luer encompassing the proximal end, and an internal lumen extending proximal of the distal end and terminating within the proximal luer; and an inner funnel catheter within the outer sheath comprising an expanding distal tip, a proximal end, a distal end located at the distal tip, a proximal luer encompassing the proximal end, and an internal lumen extending proximal of the distal end and terminating at the luer. The outer sheath and inner funnel catheter can be capable of moving telescopically with respect to each other. In some examples, a slider mechanism or rotating knob located on one of the proximal luers can be used to actuate the relative motion.Type: GrantFiled: November 24, 2020Date of Patent: December 12, 2023Assignee: NEURAVI LIMITEDInventors: Brendan Casey, Karl Keating, Ronald Kelly, David Vale
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Publication number: 20230381482Abstract: An introducer tool for use with a vascular entryway system and method. While a radially self-expanding distal section of an aspiration catheter is in a radially non-compressed state, an aspiration catheter is pre-assembled into a flared proximal section of the introducer tool. Together as a single unit, the introducer tool with the aspiration catheter pre-assembled therein is introduced into a hemostasis valve and a tapered guide sheath luer. The aspiration catheter is pushed through the introducer tool. While traversing the compressing section of the lumen of the shaft of the introducer tool and/or the tapered inner profile of a tapered guide sheath luer, the radially self-expanding distal section of the aspiration catheter is radially compressed to be receivable in a lumen of a guide sheath catheter. While the radially self-expanding distal section is radially compressed, the aspiration catheter is slid into the lumen of the guide sheath catheter.Type: ApplicationFiled: May 4, 2023Publication date: November 30, 2023Inventors: Patrick GRIFFIN, David VALE, Karl KEATING, Thomas O'MALLEY, Lucy CARRAGHER, Ronald KELLY, Aidan DUFFY, Declan LEE, Paulo RATOLA
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Publication number: 20230372670Abstract: The designs disclosed herein are for a clot retrieval catheter with a large bore shaft and an expandable distal tip section. The catheter includes proximal elongate shaft comprising a distal end, a longitudinal axis, and a shaft braid member comprising a plurality of braid wires. The expandable distal tip section is located proximate the distal end of the proximal elongate shaft. The expandable distal tip sections can vary in design. In one example, the distal tip section includes a longitudinal array of hoops. The plurality of braid wires can be formed monolithically with the array of hoops. In another example, the distal tip section can include two sets of opposing ribs. A first rib can be formed from a first wire of the plurality of braid wires, and a second rib can be formed from a second wire of the plurality of braid wire.Type: ApplicationFiled: March 28, 2023Publication date: November 23, 2023Applicant: Neuravi LimitedInventor: Karl KEATING
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Publication number: 20230363775Abstract: The systems and devices disclosed herein are for a clot retrieval catheter that can have a proximal elongate body with a lumen and a distal tip expandable to a diameter larger than the outer sheath through which it is delivered. The distal tip can have a flexible metallic support frame to provide radial scaffolding and the ability for further flexible expansion when ingesting a clot. The support frame can be designed so that the expanding movement is focused in a portion of the circumference through a plurality of support hoops that can collapse for deliverability, but can expand for aspiration. The designs can be sufficiently flexible to navigate tortuous anatomy but recover to maintain the inner diameter of the lumen when displaced in a vessel.Type: ApplicationFiled: April 25, 2023Publication date: November 16, 2023Applicant: Neuravi LimitedInventors: Karl KEATING, David VALE, Ronald KELLY
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Patent number: 11779364Abstract: A clot retrieval catheter can have an expansile distal tip for flow restriction/arrest and improved aspiration efficiency and a large, distal facing mouth into which clots or other obstructions can be retrieved. The tip can be formed from a distal ring of leaflets or hoops. One or more pull cables can be retracted to actuate and radially expand the expansile distal tip. The clot retrieval catheter can have a catheter shaft with flexibility-adding features proximal of the tip. The catheter shaft can be a multi-lumen configuration with a large catheter lumen for passing auxiliary devices and directing aspiration and one or more guide lumens which can route the pull cables to the leaflets or hoops of the expansile tip. A flexible, low-modulus membrane can be disposed around at least a portion of the expansile tip and catheter shaft.Type: GrantFiled: November 25, 2020Date of Patent: October 10, 2023Assignee: NEURAVI LIMITEDInventors: Brendan Casey, Karl Keating, Ronald Kelly, David Vale
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Patent number: 11759217Abstract: A clot retrieval catheter can have a tailored, highly flexible body section capable of navigating tortuous routes and an expandable tip for local flow restriction/arrest. The body can be a support tube of struts with a plurality of ribs and one or more axial spines. The support tube can also be a tubular section with a pattern of radial slots to increase flexibility while inhibiting kinking and binding. The ribs and spines can have strut widths which vary along the length of the support tube or can have curves with a non-planar cross section. The ribs can be formed such that they can move when subjected to the loads of a thrombectomy procedure. The structure of the support tube can also be a braided or woven pattern of strands. The support tube can also have a polymer jacket or membrane disposed around at least a portion of the structure.Type: GrantFiled: April 7, 2020Date of Patent: September 19, 2023Assignee: Neuravi LimitedInventors: Karl Keating, Ronald Kelly, David Vale
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Publication number: 20230263544Abstract: A clot retrieval catheter can have a tailored, highly flexible body section capable of navigating tortuous routes and an expandable tip for local flow restriction/arrest. The body can be a support tube of struts with a plurality of ribs and one or more axial spines. The support tube can also be a tubular section with a pattern of radial slots to increase flexibility while inhibiting kinking and binding. The ribs and spines can have strut widths which vary along the length of the support tube or can have curves with a non-planar cross section. The ribs can be formed such that they can move when subjected to the loads of a thrombectomy procedure. The structure of the support tube can also be a braided or woven pattern of strands. The support tube can also have a polymer jacket or membrane disposed around at least a portion of the structure.Type: ApplicationFiled: April 28, 2023Publication date: August 24, 2023Applicant: Neuravi LimitedInventors: Karl KEATING, Ronald KELLY, David VALE
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Publication number: 20230233218Abstract: An aspiration clot retrieval catheter to have profiled guidewire for deliverability that transitions at a proximal joint to a distal tubular section with a lumen for directing aspiration and facilitating the smooth passage of other products in performing mechanical thrombectomy procedures. The joint can have a low-profile proximal strut formed integrally with the distal tubular section and configured to interlock with a distal portion of the guidewire so that there is a smooth transition of stiffness between the guidewire and the tubular portion of the catheter to improve trackability and decrease the likelihood of kinking. The distal tubular section of the proximal joint can also have features to tailor flexibility. The distal tubular section can be configured to push radially outward to form a seal with an outer catheter to optimize aspiration transmission to the distal mouth of the aspiration clot retrieval catheter.Type: ApplicationFiled: March 24, 2023Publication date: July 27, 2023Applicant: Neuravi LimitedInventors: Karl KEATING, Ronald KELLY, David VALE
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Patent number: 11672641Abstract: A vascular filter system comprises a vascular filter (1), a clamp device (50), and a delivery catheter (51). The filter (1) comprises filter elements (6). When used without the clamp device (50), the filter elements (6) move from a closed state to an open state upon elapse of a predetermined period of time. In the closed state the filter elements (6) capture thrombus passing through the inferior vena cava (2). The delivery catheter (51) is employed to deliver the clamp device (50) to the filter (1) after the filter (1) has been deployed in the inferior vena cava (2). The clamp device (50) engages with the filter elements (6) of the filter (1) to clamp the filter (1) in the closed state beyond elapse of the predetermined period of time. Because of the presence of the clamp device (50), the filter elements (6) are no longer free to move from the closed state to the open state upon elapse of the predetermined period of time.Type: GrantFiled: March 3, 2020Date of Patent: June 13, 2023Assignee: Novate Medical LimitedInventors: Paul Gilson, Steven Horan, Karl Keating, Aidan Goggin
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Patent number: 11672639Abstract: A vascular filter device (1) has a support (2) for engaging the wall of a blood vessel. A filter has filter elements (5) having proximal segments (10) connected to the support (3) and distal segments at least temporarily restrained at a distal apex (7) by a holder when in a filtering closed position. At least one filter element (5) extends radially outwardly with respect to a device longitudinal axis when unconstrained. The filter element may extend in a curve with a concave portion facing radially outwardly in an unconstrained configuration.Type: GrantFiled: May 4, 2020Date of Patent: June 13, 2023Assignee: Novate Medical LimitedInventors: Paul Gilson, Steven Horan, Karl Keating, Dara Finneran, Jacqueline O'Gorman, Damien Ryan, Megan Macdonagh, Paul Bateman