Patents by Inventor Karl Müller
Karl Müller has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240148825Abstract: The current disclosure provides methods and composition for treatment of autoimmune and inflammatory conditions, including systemic lupus erythematosus and antiphospholipid syndrome. Certain aspects of the disclosure are directed to methods for treatment of an autoimmune or inflammatory condition comprising administering a composition comprising a therapeutically effective amount of NAPc2 or NAPc2/proline. Further aspects include pharmaceutical compositions comprising NAPc2 or NAPc2/proline and, in some cases, one or more additional anti-inflammatory agents.Type: ApplicationFiled: June 9, 2022Publication date: May 9, 2024Applicant: UNIVERSITÄTSMEDIZIN DER JOHANNES GUTENBERG-UNIVERSITÄT MAINZInventors: Wolfram RUF, Nadine MÜLLER-CALLEJA, Karl LACKNER, Julia WEINMANN-MENKE
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Patent number: 11964646Abstract: A foot brake valve (2?) of a pneumatic brake system in a motor vehicle has an installation plate (4?), on which a brake pedal (14) is pivotably mounted and to which a housing (18?) of a control unit (16, 26) is fastened. A spring-loaded plunger piston (36) in actuating contact with the brake pedal (14) is guided axially movably in an annular collar (50) projecting upward out of the installation plate (4?). For fastening the housing (18?) of the control unit (16, 26) to the installation plate (4?), the housing (18?) has an intermediate flange (48) which is screw-connected to the main part of the housing (18?) and has the annular collar (50). The intermediate flange (48) is coaxially rotatably about a vertical central axis (32), and is connectable in non-positively locking fashion to the installation plate (4?) via a releasable clamping connection (62).Type: GrantFiled: October 17, 2019Date of Patent: April 23, 2024Assignee: ZF CV Systems Europe BVInventors: Peter Beier, Ulrich Couppee, Reiner Hölscher, Gerhard Martini, Karl-Heinz Riediger-Janisch, Olaf Bindseil, Petra Elze, Alexander Fabian, Gerrit Glondajewski, Sven Homann, Jan Hörstmann, Thomas Müller
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Patent number: 11922274Abstract: Quantum dot devices with three of more accumulation gates provided over a single row of a quantum dot formation region are disclosed. Each accumulation gate is electrically coupled to a respective doped region. In this manner, multiple single electron transistors (SETs) are provided along the row. Side and/or center screening gates may be used to apply microwave pulses for qubit control and to control electrostatics so that source and drain regions of the multiple SETs with quantum dots formed along the single row of a quantum dot formation region are sufficiently isolated from one another. Such quantum dot devices provide strong spatial localization of the quantum dots, good control over quantum dot interactions and manipulation, good scalability in the number of quantum dots included in the device, and/or design flexibility in making electrical connections to the quantum dot devices to integrate the quantum dot devices in larger computing devices.Type: GrantFiled: May 18, 2021Date of Patent: March 5, 2024Assignee: Intel CorporationInventors: Hubert C. George, James S. Clarke, Ravi Pillarisetty, Brennen Karl Mueller, Stephanie A. Bojarski, Eric M. Henry, Roza Kotlyar, Thomas Francis Watson, Lester Lampert, Samuel Frederick Neyens
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Patent number: 11749628Abstract: Microelectronic assemblies, related devices and methods, are disclosed herein. In some embodiments, a microelectronic assembly may include a first microelectronic component having a first direct bonding region, wherein the first direct bonding region includes first metal contacts and a first dielectric material between adjacent ones of the first metal contacts; a second microelectronic component having a second direct bonding region, wherein the second direct bonding region includes second metal contacts and a second dielectric material between adjacent ones of the second metal contacts, wherein the first microelectronic component is coupled to the second microelectronic component by interconnects, and wherein the interconnects include individual first metal contacts coupled to respective individual second metal contacts; and a void between an individual first metal contact that is not coupled to a respective individual second metal contact, wherein the void is in the first direct bonding region.Type: GrantFiled: November 9, 2022Date of Patent: September 5, 2023Assignee: Intel CorporationInventors: Adel A. Elsherbini, Veronica Aleman Strong, Shawna M. Lift, Brandon M. Rawlings, Jagat Shakya, Johanna M. Swan, David M. Craig, Jeremy Alan Streifer, Brennen Karl Mueller
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Publication number: 20230074970Abstract: Microelectronic assemblies, related devices and methods, are disclosed herein. In some embodiments, a microelectronic assembly may include a first microelectronic component having a first direct bonding region, wherein the first direct bonding region includes first metal contacts and a first dielectric material between adjacent ones of the first metal contacts; a second microelectronic component having a second direct bonding region, wherein the second direct bonding region includes second metal contacts and a second dielectric material between adjacent ones of the second metal contacts, wherein the first microelectronic component is coupled to the second microelectronic component by interconnects, and wherein the interconnects include individual first metal contacts coupled to respective individual second metal contacts; and a void between an individual first metal contact that is not coupled to a respective individual second metal contact, wherein the void is in the first direct bonding region.Type: ApplicationFiled: November 9, 2022Publication date: March 9, 2023Applicant: Intel CorporationInventors: Adel A. Elsherbini, Veronica Aleman Strong, Shawna M. Liff, Brandon M. Rawlings, Jagat Shakya, Johanna M. Swan, David M. Craig, Jeremy Alan Streifer, Brennen Karl Mueller
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Patent number: 11534096Abstract: The present disclosure is related to methods, systems and apparatus for performing electrophysiological measurements utilizing three or more electrodes attached to a patient. The system in various embodiments may include three or more electrodes attached to the patient and at least one analog-to-digital converter with external circuitry electrically coupled to the electrodes. The system may further include a microprocessor for driving the analog-to-digital conversion process, various inputs and variable frequency current outputs electrically coupled to the microprocessor for receiving signals from the electrodes and sending driven current signals to the electrodes.Type: GrantFiled: February 20, 2018Date of Patent: December 27, 2022Assignee: KONINKLIJKE PHILIPS N.V.Inventors: Christoph Florian Franck, Erwin Karl Mueller
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Patent number: 11527501Abstract: Microelectronic assemblies, related devices and methods, are disclosed herein. In some embodiments, a microelectronic assembly may include a first microelectronic component having a first direct bonding region, wherein the first direct bonding region includes first metal contacts and a first dielectric material between adjacent ones of the first metal contacts; a second microelectronic component having a second direct bonding region and coupled to the first microelectronic component by the first and second direct bonding regions, wherein the second direct bonding region includes second metal contacts and a second dielectric material between adjacent ones of the second metal contacts, and wherein individual first metal contacts in the first direct bonding region are coupled to respective individual second metal contacts in the second direct bonding region; and a void between an individual first metal contact and a respective individual second metal contact.Type: GrantFiled: December 15, 2020Date of Patent: December 13, 2022Assignee: Intel CorporationInventors: Adel A. Elsherbini, Veronica Aleman Strong, Shawna M. Liff, Brandon M. Rawlings, Jagat Shakya, Johanna M. Swan, David M. Craig, Jeremy Alan Streifer, Brennen Karl Mueller
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Publication number: 20220278057Abstract: Microelectronic assemblies, and related devices and methods, are disclosed herein. For example, in some embodiments, a microelectronic assembly may a die having a front side and a back side, the die comprising a first material and conductive contacts at the front side; and a thermal layer attached to the back side of the die, the thermal layer comprising a second material and a conductive pathway, wherein the conductive pathway extends from a front side of the thermal layer to a back side of the thermal layer.Type: ApplicationFiled: May 19, 2022Publication date: September 1, 2022Applicant: Intel CorporationInventors: Adel A. Elsherbini, Patrick Morrow, Henning Braunisch, Kimin Jun, Brennen Karl Mueller, Shawna M. Liff, Johanna M. Swan, Paul B. Fischer
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Publication number: 20210372789Abstract: The disclosure relates to a method for radially aligning wheelsets of rail vehicles relative to a coordinate system of a wheelset diagnosis tool and/or wheelset machine tool, which method can be implemented quickly with sufficient precision and comprises the following steps: a) positioning the wheelset at a working position of the tool; b) defining a tool-side coordinate system in an assumed wheel centre point of each wheel, where an X-axis adopts a vertical extent, a Y-axis adopts a horizontal extent and a Z-axis describes the resulting depth extent of the wheel; c) measuring the distance of the wheel backs with respect to one another and defining the Z-position=0 on each wheel back; d) defining a unique Z-position for each measuring point; e) positioning each measuring sensor at the specified Z-position; f) measuring the X-position of each measuring point; g) aligning the wheelset by vertically displacing one of the wheels in order to match the X-positions of the measuring points of two wheels.Type: ApplicationFiled: October 11, 2019Publication date: December 2, 2021Inventors: John Oliver NAUMANN, Sascha THOLEN, Karl MÜLLER
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Publication number: 20190387997Abstract: The present disclosure is related to methods, systems and apparatus for performing electrophysiological measurements utilizing three or more electrodes attached to a patient. The system in various embodiments may include three or more electrodes attached to the patient and at least one analog-to-digital converter with external circuitry electrically coupled to the electrodes. The system may further include a microprocessor for driving the analog-to-digital conversion process, various inputs and variable frequency current outputs electrically coupled to the microprocessor for receiving signals from the electrodes and sending driven current signals to the electrodes.Type: ApplicationFiled: February 20, 2018Publication date: December 26, 2019Inventors: Christoph Florian FRANCK, Erwin Karl MUELLER
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Patent number: 10449931Abstract: A lock system for access authorization in a motor vehicle, having a first device which has at least two states and is embodied as a control device, and having an associated second device which is embodied in the manner of an electronic key, an ID signal transmitter, a chip card or the like. The two devices have transmitters and/or receivers for electromagnetic signals. At least one of the signals transmitted between the second device and the first device is an encoded operating signal for authenticating the second device, with the result that after a positive evaluation of the transmitted operating signal when the second device is authorized it is possible to bring about a change in the state of the first device.Type: GrantFiled: November 2, 2017Date of Patent: October 22, 2019Assignee: Marquardt GmbHInventors: Karl Mueller, Wolfgang Stehle, Stefan Vogel
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Publication number: 20180118166Abstract: A lock system for access authorization in a motor vehicle, having a first device which has at least two states and is embodied as a control device, and having an associated second device which is embodied in the manner of an electronic key, an ID signal transmitter, a chip card or the like. The two devices have transmitters and/or receivers for electromagnetic signals. At least one of the signals transmitted between the second device and the first device is an encoded operating signal for authenticating the second device, with the result that after a positive evaluation of the transmitted operating signal when the second device is authorized it is possible to bring about a change in the state of the first device.Type: ApplicationFiled: November 2, 2017Publication date: May 3, 2018Applicant: Marquardt GmbHInventors: Karl MUELLER, Wolfgang STEHLE, Stefan VOGEL
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Patent number: 9848671Abstract: In an item of footwear having a sole and an upper, the sole includes at least one upper layer, which is directed towards the upper, and at least one lower layer, which is directed away from the upper. The upper layer and the lower layer are made of materials having different levels of elasticity, density or hardness. The side of the sole which is directed towards the upper forms a bearing surface for the foot, with a heel zone and a ball-of-the-foot zone. The lower layer passes through the upper layer at least in part such that a bearing surface is formed by regions of the lower layer and of the upper layer. This construction makes it possible to combine the different materials' properties in the region of the bearing surface.Type: GrantFiled: October 21, 2011Date of Patent: December 26, 2017Assignee: Joya Schuhe AGInventor: Karl Mueller
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Patent number: 9789830Abstract: The invention relates to an energy supply circuit of electric components, in particular for a motor vehicle, having an accumulator, wherein a discharge monitoring circuit monitors the energy stored in the accumulator. If the energy stored in the accumulator falls below a threshold value, the discharge monitoring circuit switches off the energy supply at least of individual components, in particular of all components.Type: GrantFiled: January 24, 2014Date of Patent: October 17, 2017Assignee: Marquardt GmbHInventors: Karl Müller, Matthias Reckermann
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Patent number: 9740096Abstract: In microelectronic applications, it is often desired to deposit and pattern a permanent dielectric film in order to electrically and mechanically isolate components. Photo-patternable dielectrics are attractive for these uses because of their reduced time and cost requirements. These permanent dielectrics should be high-speed, positive-tone, and aqueous-developable. This type of patternability may be achieved by using a chemically amplified deprotection reaction of tert-butoxycarbonate or tert-butyl acrylate catalyzed by a photo-inducible acid.Type: GrantFiled: June 28, 2013Date of Patent: August 22, 2017Assignee: Georgia Tech Research CorporationInventors: Brennen Karl Mueller, Paul A. Kohl
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Publication number: 20150357549Abstract: The present invention relates to a method for solid-state synthesis of ceramic materials, in particular of oxide materials or cuprates, comprising or consisting of the step of providing starting material in amounts effective to produce the ceramic material and, thereafter, applying a treatment to said material by use of a solid-state reaction therein, said reaction being performed by irradiating said material from at least one light source with ultraviolet light. The present invention also relates to methods for producing thin films and to a use of the method for production of high-temperature superconductors.Type: ApplicationFiled: January 15, 2013Publication date: December 10, 2015Inventors: Alex Karl MÜLLER, Alexander SHENGELAIA
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Publication number: 20150160551Abstract: In microelectronic applications, it is often desired to deposit and pattern a permanent dielectric film in order to electrically and mechanically isolate components. Photo-patternable dielectrics are attractive for these uses because of their reduced time and cost requirements. These permanent dielectrics should be high-speed, positive-tone, and aqueous-developable. This type of patternability may be achieved by using a chemically amplified deprotection reaction of tert-butoxycarbonate or tert-butyl acrylate catalyzed by a photo-inducible acid.Type: ApplicationFiled: June 28, 2013Publication date: June 11, 2015Applicant: Georgia Tech Research CorporationInventors: Brennen Karl Mueller, Paul A. Kohl
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Patent number: 8919012Abstract: The present invention relates to functional footwear of a new concept, which adapts itself to the shape of a foot and gives a soft feeling when walking The footwear includes: an upper foot fixing section (1) for covering and fixing an upper portion of a foot; and a foot supporting section (8) attached to the upper foot fixing section for supporting a lower portion of the foot. The foot supporting section comprises a soft resilient mat (2) which can be deformed according to the shape of the foot. The footwear has a simple structure and can give a feeling of walking barefoot on a sponge mat or on a lawn like a extreme-soft-elastic carpet to provide complete comfort to the wearer during walking.Type: GrantFiled: December 20, 2012Date of Patent: December 30, 2014Assignee: Kybun AGInventors: Karl Mueller, Matthias Mueller
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Publication number: 20140256525Abstract: A training mat (1) comprising an integrally expanded plastics material, in particular consisting of a polyurethane, with a support surface (2), a standing surface (3) and a plurality of side surfaces (4, 4?, 4?, 4??), wherein a cross-sectional surface (5) perpendicular to the support surface (2) is configured approximately in a wedge-shaped manner.Type: ApplicationFiled: November 16, 2012Publication date: September 11, 2014Inventor: Karl Mueller
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Patent number: D721244Type: GrantFiled: March 20, 2013Date of Patent: January 20, 2015Assignee: Steelcase Werndl AGInventors: Karl Mueller, John Small