Abstract: A system and method for building and providing a universal product configuration system for arbitrary domains allows one or more domain experts to create and maintain domain-specific conceptual frameworks and associated knowledge sets such that users can select and configure valid products and generate meaningful output. Multiple domains can be represented simultaneously, allowing multiple conceptual framework/knowledge set pairs to be used in any combination so that products from their respective conceptual frameworks can be shared within and across domains. The present invention further allows products to be converted and imported from legacy data sources, and provides for the standardization of product configuration systems, including the critical data embodied therein, within a single domain as well as across arbitrary multiple domains.

Abstract: Nanoparticulate crystalline drug substances formulated in an aqueos phase emulsified in oil, are able to be made at less than 1000 nm size and provide increased bioavailability and lymphatic uptake following oral administration.

Abstract: Nanoparticulate crystalline drug substances formulated in an aqueos phase emulsified in oil, are able to be made at less than 1000 nm size and provide increased bioavailability and lymphatic uptake following oral administration.

Abstract: A composition comprising a crystalline NSAID having polyvinylpyrrolidone adsorbed on the surface thereof in an amount sufficient to maintain an effective average particle size of less than about 1000 nm, hygroscopic sugar and sodium lauryl sulfate exhibit greatly reduced gastric irritation following oral administration and/or hastened onset of action due to the substantial redispersion of the solid formulation to nanoparticles in gastric fluid.