Patents by Inventor Karl T. Riabowol

Karl T. Riabowol has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of modulating p53 activity
    Patent number: 6420136
    Abstract: This invention relates to a method for modulating the activity of the protein p53 in cells by the addition of a peptide or protein having p33ING1 biological activity or a nucleic acid coding for such a peptide or protein.
    Type: Grant
    Filed: September 24, 1998
    Date of Patent: July 16, 2002
    Assignees: University Technologies International, Inc., Board of Trustees of the University of Illinois
    Inventors: Karl T. Riabowol, Igor Garkavtsev, Andrei Gudkov
  • Monoclonal antibodies to ING1 isoforms
    Publication number: 20020039735
    Abstract: The present invention relates to monoclonal antibodies against the candidate tumor suppressor ING1. A combination of these monoclonal antibodies can detect low levels of endogenous ING1 proteins, and it can also detect at least two different ING1 isoforms, p33ING1b and p47ING1a.
    Type: Application
    Filed: June 4, 2001
    Publication date: April 4, 2002
    Inventors: Karl T. Riabowol, Donna Boland
  • Cyclin D1 negative regulatory activity
    Patent number: 5877161
    Abstract: Use of cyclin D1 as a negative regulator of cell proliferation is disclosed. Overexpression of cyclin D1 blocks cell growth, while blocking cyclin D1 expression promotes cell proliferation.
    Type: Grant
    Filed: February 15, 1996
    Date of Patent: March 2, 1999
    Assignee: University Technologies International Inc.
    Inventor: Karl T. Riabowol
  • Cyclin D1 negative regulatory activity
    Patent number: 5514571
    Abstract: Use of cyclin D1 as a negative regulator of cell proliferation is disclosed. Overexpression of cyclin D1 blocks cell growth, while blocking cyclin D1 expression promotes cell proliferation.
    Type: Grant
    Filed: February 28, 1995
    Date of Patent: May 7, 1996
    Assignee: University Technologies International Inc.
    Inventor: Karl T. Riabowol