Patents by Inventor Karlheinz Enssle

Karlheinz Enssle has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Storage-stable, liquid fibrinogen formulation
    Patent number: 7045601
    Abstract: The present invention relates to a novel storage-stable formulation for fibrinogen in liquid or viscous liquid form comprising divalent metal ions. The fibrinogen formulation may comprise other conventional formulation ingredients and particularly preferably comprises a complexing agent. The invention further relates to the production and use of the fibrinogen formulation of the invention.
    Type: Grant
    Filed: August 8, 2003
    Date of Patent: May 16, 2006
    Assignee: ZLB BEHRING GmbH
    Inventors: Hubert Metzner, Uwe Liebing, Gerhardt Kumpe, Stefan Schulte, Volker Gawantka, Karlheinz Enssle
  • Storage-stable, liquid fibrinogen formulation
    Publication number: 20050080009
    Abstract: The present invention relates to a novel storage-stable formulation for fibrinogen in liquid or viscous liquid form comprising divalent metal ions. The fibrinogen formulation may comprise other conventional formulation ingredients and particularly preferably comprises a complexing agent. The invention further relates to the production and use of the fibrinogen formulation of the invention.
    Type: Application
    Filed: August 8, 2003
    Publication date: April 14, 2005
    Inventors: Hubert Metzner, Uwe Liebing, Gerhardt Kumpe, Stefan Schulte, Volker Gawantka, Karlheinz Enssle
  • Method for detecting and determining mediators
    Patent number: 6475717
    Abstract: The invention relates to a method for detecting and determining mediators and/or their derivatives in fluids, the mediator being detected directly or indirectly with the aid of a recombinant, soluble receptor for the mediator to be detected.
    Type: Grant
    Filed: July 25, 1997
    Date of Patent: November 5, 2002
    Assignee: Dade Behring Marburg GmbH
    Inventors: Karlheinz Enssle, Roland Kurrle, Klaus-Dieter Langner, Leander Lauffer, Josef-Urban Pauly, Friedrich-Robert Seiler
  • Use of the IL-4 receptor for the therapy prophylaxis and diagnosis of allergic viral parasitic and bacterial diseases and of fungal infections
    Patent number: 6328954
    Abstract: The use of the IL-4 receptor for the therapy, prophylaxis and diagnosis of allergic, viral, parasitic and bacterial diseases and of fungal infections. The invention relates to the use of the IL-4 receptor or of derivatives thereof for the therapy, prophylaxis and diagnosis of allergic, viral, parasitic and bacterial diseases and of fungal infections.
    Type: Grant
    Filed: July 29, 1999
    Date of Patent: December 11, 2001
    Assignee: Aventis Pharma Deutschland GmbH
    Inventors: Karlheinz Enssle, Roland Kurrle, Leander Lauffer, Friedrich-Robert Seiler
  • IL-4 receptor for the therapy, prophylaxis and diagnosis of allergic, viral, and bacterial diseases and of fungal infections
    Patent number: 6210661
    Abstract: The IL-4 receptor for the therapy, prophylaxis and diagnosis of allergic, viral, parasitic and bacterial diseases and of fungal infections. The invention relates to the il-4 receptor or variants thereof for the therapy, prophylaxis and diagnosis of allergic, viral, parasitic and bacterial diseases and of fungal infections.
    Type: Grant
    Filed: August 5, 1996
    Date of Patent: April 3, 2001
    Assignee: Aventis Pharma Deutschland GmbH
    Inventors: Karlheinz Enssle, Roland Kurrle, Leander Lauffer, Friedrich-Robert Seiler
  • Magnetic protein conjugates, a process for the preparation thereof, and the use thereof
    Patent number: 5672687
    Abstract: The invention relates to magnetic protein conjugates of the formula I ##STR1## in which M represents a dispersible magnetically reacting material or particle which carries aminogroups, Ig represents a protein which carries one or more mercapto groups, and X represents an organic chemical structure which links the two ligands by chemical means, to a process for the preparation of protein conjugates of the formula I, and to the use of conjugates of this type for removing cells or soluble bioorganic molecules or components from aqueous salt solutions or body fluids, and to the use thereof within the framework of a diagnostic method or as a diagnostic aid.
    Type: Grant
    Filed: January 19, 1995
    Date of Patent: September 30, 1997
    Assignee: Behringwerke Aktiengesellschaft
    Inventors: Peter Hermentin, Reiner Donges, Karlheinz Enssle, Roland Kurrle, Friedrich Robert Seiler
  • Magnetic protein conjugates, a process for the preparation thereof and the use thereof
    Patent number: 5095097
    Abstract: The invention relates to magnetic protein conjugates of the formula IM--NH--CO--(CH.sub.2).sub.n --S--P' Iwith n=1-6, preferably with a n=1 or 2 and particularly preferably with n=1, in which M is a dispersible, magnetically reacting material or particle which carries amino groups, and P' is a protein, to a process for the preparation thereof and to the use thereof for the specific removal of cells or soluble antigens, receptors, substrates, cofactors or carbohydrate determinants from aqueous salt solutions or body fluids or as part of a diagnostic method or as a diagnostic aid, preferably for the removal of cells, preferably for bone marrow depletion or for HLA typing.
    Type: Grant
    Filed: June 15, 1990
    Date of Patent: March 10, 1992
    Assignee: Behringwerke Aktiengesellschaft
    Inventors: Peter Hermentin, Reiner Donges, Udo Franssen, Karlheinz Enssle, Heinz-Jurgen Friesen