Patents by Inventor Karsten Henco

Karsten Henco has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11975120
    Abstract: A chitosan for use in an antimicrobial treatment of a patient's tissue and a pharmaceutical composition comprising a chitosan for use in an antimicrobial treatment of a patient's tissue. A method of treating a microbial infection, the method comprising the step of administering to a patient an effective amount of a chitosan and an aqueous solution comprising chitosan. A chitosan or a pharmaceutical composition comprising a chitosan for use in an epithelial cell growth stimulating treatment of a patient's tissue. A method of stimulating the growth of epithelial cells the method comprising the step of administering to a patient or to an epithelial cells containing cell culture an effective amount of a chitosan or a pharmaceutical composition comprising chitosan. A tissue dressing material characterized in that it consists of chitosan or a chitosan comprising composition.
    Type: Grant
    Filed: March 18, 2022
    Date of Patent: May 7, 2024
    Assignee: Medoderm Gmbh
    Inventors: Rivelino Montenegro, Thomas Freier, Karsten Henco
  • Publication number: 20240093151
    Abstract: The present invention relates to methods for producing immuno-stimulatory antigen-presenting cells. The present invention further relates to the use of such cells for treating patients suffering from hyper-proliferative disease such as cancer.
    Type: Application
    Filed: April 12, 2023
    Publication date: March 21, 2024
    Inventors: Günter BAUER, Richard EDELSON, Karsten HENCO, Justin DUCKWORTH
  • Publication number: 20230381217
    Abstract: Liquid compositions are used to differentially promote the growth of the microbiome. The liquid composition forms a membrane when applied to the skin of a subject. The liquid composition as well as the membrane comprise chitosan or a salt thereof with a degree of acetylation of 20% or less and at least one additional agent. Also disclosed are pharmaceutical compositions for use in the prevention or reduction of skin irritation, allergy and/or an infectious disease.
    Type: Application
    Filed: October 14, 2021
    Publication date: November 30, 2023
    Applicant: Medoderm GMBH
    Inventors: Günter Bauer, Manfred Beleut, Karsten Henco
  • Publication number: 20230136330
    Abstract: A chitosan for use in an antimicrobial treatment of a patient's tissue and a pharmaceutical composition comprising a chitosan for use in an antimicrobial treatment of a patient's tissue. A method of treating a microbial infection, the method comprising the step of administering to a patient an effective amount of a chitosan and an aqueous solution comprising chitosan. A chitosan or a pharmaceutical composition comprising a chitosan for use in an epithelial cell growth stimulating treatment of a patient's tissue. A method of stimulating the growth of epithelial cells the method comprising the step of administering to a patient or to an epithelial cells containing cell culture an effective amount of a chitosan or a pharmaceutical composition comprising chitosan. A tissue dressing material characterized in that it consists of chitosan or a chitosan comprising composition.
    Type: Application
    Filed: March 18, 2022
    Publication date: May 4, 2023
    Inventors: Rivelino Montenegro, Thomas Freier, Karsten Henco
  • Publication number: 20220280562
    Abstract: The present invention relates to methods for producing immuno-stimulatory autologous dendritic cells. The present invention further relates to the use of such cells for treating patients suffering from hyper-proliferative disease such as cancer.
    Type: Application
    Filed: November 18, 2021
    Publication date: September 8, 2022
    Inventors: Günter BAUER, Justin DUCKWORTH, Robert TIGELAAR, Richard EDELSON, Michael GIRARDI, Karsten HENCO, Adrian HAYDAY
  • Publication number: 20220259556
    Abstract: The present invention relates to methods for producing immuno-suppressive dendritic cells. The present invention further relates to the use of such cells for treating patients suffering from autoimmune diseases, hypersensitivity diseases, rejection on solid-organ transplantation and/or Graft-versus-Host disease.
    Type: Application
    Filed: October 21, 2021
    Publication date: August 18, 2022
    Inventors: Karsten HENCO, Gunter BAUER, Justin DUCKWORTH, Adrian HAYDAY, Richard EDELSON, Robert TIGELAAR, Michael GIRARDI
  • Publication number: 20220211606
    Abstract: The present invention relates to liquid compositions as well as the use of liquid compositions for differentially promoting the growth of the microbiome. The liquid composition forms a membrane of the invention when applied to the skin of a subject. The liquid composition as well as the membrane comprise chitosan or a salt thereof with a degree of acetylation of 20% or less and at least one further agent. The present invention further relates to pharmaceutical compositions for the treatment of dysbiosis.
    Type: Application
    Filed: March 30, 2020
    Publication date: July 7, 2022
    Inventors: Günter Bauer, Manfred Beleut, Karsten Henco
  • Patent number: 11311644
    Abstract: A chitosan for use in an antimicrobial treatment of a patient's tissue and a pharmaceutical composition comprising a chitosan for use in an antimicrobial treatment of a patient's tissue. A method of treating a microbial infection, the method comprising the step of administering to a patient an effective amount of a chitosan and an aqueous solution comprising chitosan. A chitosan or a pharmaceutical composition comprising a chitosan for use in an epithelial cell growth stimulating treatment of a patient's tissue. A method of stimulating the growth of epithelial cells the method comprising the step of administering to a patient or to an epithelial cells containing cell culture an effective amount of a chitosan or a pharmaceutical composition comprising chitosan. A tissue dressing material characterized in that it consists of chitosan or a chitosan comprising composition.
    Type: Grant
    Filed: July 1, 2019
    Date of Patent: April 26, 2022
    Assignee: Medoderm GmbH
    Inventors: Rivelino Montenegro, Thomas Freier, Karsten Henco
  • Publication number: 20220112462
    Abstract: The present invention relates to methods for producing immuno-stimulatory autologous dendritic cells. The present invention further relates to the use of such cells for treating patients suffering from hyper-proliferative disease such as cancer.
    Type: Application
    Filed: October 26, 2021
    Publication date: April 14, 2022
    Inventors: Karsten HENCO, Günter BAUER, Justin DUCKWORTH, Adrian HAYDAY, Richard EDELSON, Robert TIGELAAR, Michael GIRARDI
  • Publication number: 20210361754
    Abstract: A treatment of Alzheimer's disease and other disorders involving protein misfolding or aggregation is provided by enhancing or sustaining an antibody response against predominantly directed against pathological protein aggregates or neo-epitopes present on pathogenic forms of said protein or protein complex. Furthermore, therapeutic methods are described, wherein ex vivo stimulated antigen-selected peripheral blood lymphocytes are regrafted into the cognate donor.
    Type: Application
    Filed: December 9, 2020
    Publication date: November 25, 2021
    Inventors: Karsten HENCO, Roger NITSCH, Jan GRIMM, Anja ZELLER, Marcel MAIER
  • Patent number: 11179417
    Abstract: The present invention relates to methods for producing immuno-stimulatory autologous dendritic cells. The present invention further relates to the use of such cells for treating patients suffering from hyper-proliferative disease such as cancer.
    Type: Grant
    Filed: July 3, 2015
    Date of Patent: November 23, 2021
    Assignees: Transimmune AG, Yale University
    Inventors: Gunter Bauer, Justin Duckworth, Robert Tigelaar, Richard Edelson, Michael Girardi, Karsten Henco, Adrian Hayday
  • Patent number: 10874725
    Abstract: A treatment of Alzheimer's disease and other disorders involving protein misfolding or aggregation is provided by enhancing or sustaining an antibody response against predominantly directed against pathological protein aggregates or neo-epitopes present on pathogenic forms of said protein or protein complex. Furthermore, therapeutic methods are described, wherein ex vivo stimulated antigen-selected peripheral blood lymphocytes are regrafted into the cognate donor.
    Type: Grant
    Filed: December 18, 2017
    Date of Patent: December 29, 2020
    Assignee: New York University
    Inventors: Karsten Henco, Roger Nitsch, Jan Grimm, Anja Zeller, Marcel Maier
  • Publication number: 20190321511
    Abstract: A chitosan for use in an antimicrobial treatment of a patient's tissue and a pharmaceutical composition comprising a chitosan for use in an antimicrobial treatment of a patient's tissue. A method of treating a microbial infection, the method comprising the step of administering to a patient an effective amount of a chitosan and an aqueous solution comprising chitosan. A chitosan or a pharmaceutical composition comprising a chitosan for use in an epithelial cell growth stimulating treatment of a patient's tissue. A method of stimulating the growth of epithelial cells the method comprising the step of administering to a patient or to an epithelial cells containing cell culture an effective amount of a chitosan or a pharmaceutical composition comprising chitosan. A tissue dressing material characterized in that it consists of chitosan or a chitosan comprising composition.
    Type: Application
    Filed: July 1, 2019
    Publication date: October 24, 2019
    Applicant: MEDODERM GMBH
    Inventors: Rivelino Montenegro, Thomas Freier, Karsten Henco
  • Publication number: 20180195042
    Abstract: The present invention relates to methods for producing immuno-stimulatory antigen-presenting cells. The present invention further relates to the use of such cells for treating patients suffering from hyper-proliferative disease such as cancer.
    Type: Application
    Filed: July 4, 2016
    Publication date: July 12, 2018
    Inventors: Gunter BAUER, Richard EDELSON, Karsten HENCO, Justin DUCKWORTH
  • Publication number: 20180110845
    Abstract: A treatment of Alzheimer's disease and other disorders involving protein misfolding or aggregation is provided by enhancing or sustaining an antibody response against predominantly directed against pathological protein aggregates or neo-epitopes present on pathogenic forms of said protein or protein complex. Furthermore, therapeutic methods are described, wherein ex vivo stimulated antigen-selected peripheral blood lymphocytes are regrafted into the cognate donor.
    Type: Application
    Filed: December 18, 2017
    Publication date: April 26, 2018
    Inventors: Karsten HENCO, Roger NITSCH, Jan GRIMM, Anja ZELLER, Marcel MAIER
  • Publication number: 20170128490
    Abstract: The present invention relates to methods for producing immuno-stimulatory autologous dendritic cells. The present invention further relates to the use of such cells for treating patients suffering from hyper-proliferative disease such as cancer.
    Type: Application
    Filed: July 3, 2015
    Publication date: May 11, 2017
    Inventors: GUNTER BAUER, JUSTIN DUCKWORTH, ROBERT TIGELAAR, RICHARD EDELSON, MICHAEL GIRARDI, KARSTEN HENCO, ADRIAN HAYDAY
  • Publication number: 20160354451
    Abstract: A treatment of Alzheimer's disease and other disorders involving protein misfolding or aggregation is provided by enhancing or sustaining an antibody response against predominantly directed against pathological protein aggregates or neo-epitopes present on pathogenic forms of said protein or protein complex. Furthermore, therapeutic methods are described, wherein ex vivo stimulated antigen-selected peripheral blood lymphocytes are regrafted into the cognate donor.
    Type: Application
    Filed: June 9, 2016
    Publication date: December 8, 2016
    Inventors: Karsten Henco, Roger Nitsch, Jan Grimm, Anja Zeller, Marcel Maier
  • Publication number: 20160298082
    Abstract: The present invention relates to methods for producing immuno-stimulatory autologous dendritic cells. The present invention further relates to the use of such cells for treating patients suffering from hyper-proliferative disease such as cancer.
    Type: Application
    Filed: January 2, 2014
    Publication date: October 13, 2016
    Inventors: Karsten HENCO, Gunter BAUER, Justin DUCKWORTH, Adrian HAYDAY, Richard EDELSON, Robert TIGELAAR, Michael GIRARDI
  • Patent number: 9439998
    Abstract: The present invention relates to methods for disinfecting or decontaminating a material or for preventing an infection or contamination of a material. The invention further relates to compositions which are suitable for disinfecting a material or for preventing an infection or contamination of a material and to uses of such compositions. The invention further relates to a medical use of chitosan and to a pharmaceutical composition comprising the chitosan. The invention further relates to a method of treating a microbial infection and to an aqueous solution comprising chitosan. The invention moreover relates to a chitosan or a pharmaceutical composition comprising a chitosan for an epithelial cell growth stimulating treatment of a patient's tissue and to a method of stimulating the growth of epithelial cells. The invention also relates to a tissue dressing material.
    Type: Grant
    Filed: September 1, 2010
    Date of Patent: September 13, 2016
    Assignee: Medoderm GmbH
    Inventors: Karsten Henco, Thomas Freier, Rivelino Montenegro
  • Patent number: 9370531
    Abstract: A treatment of Alzheimer's disease and other disorders involving protein misfolding or aggregation is provided by enhancing or sustaining an antibody response against predominantly directed against pathological protein aggregates or neo-epitopes present on pathogenic forms of said protein or protein complex. Furthermore, therapeutic methods are also described, wherein ex vivo stimulated antigen-selected peripheral blood lymphocytes are regrafted into the cognate donor.
    Type: Grant
    Filed: September 1, 2008
    Date of Patent: June 21, 2016
    Assignee: New York University
    Inventors: Karsten Henco, Roger Nitsch, Jan Grimm, Anja Zeller, Marcel Maier