Patents by Inventor Karthik Venkatakrishnan

Karthik Venkatakrishnan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • A METHOD FOR ENHANCING THE PHARMACOKINETICS OR INCREASING THE PLASMA CONCENTRATION OF METHYL 3-((METHYLSULFONYL)AMINO)-2-(((4-PHENYLCYCLOHEXYL)OXY)METHYL)PIPERIDINE-1-CARBOXYLATE OR A SALT THEREOF WITH AN INHIBITOR OF CYTOCHROME P450
    Publication number: 20230029486
    Abstract: Described herein are compositions comprising (a) methyl 3 -((methyl sulfonyl)amino)-2-(((4-phenylcyclohexyl)oxy)methyl)piperidine- 1 -carboxylate or a salt thereof; and (b) an agent for reducing metabolism of (a) and uses thereof.
    Type: Application
    Filed: January 7, 2021
    Publication date: February 2, 2023
    Inventors: Mark ROGGE, Helen FAESSEL, Hong LU, Karthik VENKATAKRISHNAN, Liming ZHANG, John WAGNER
  • Methods of treating cancer in pediatric patients
    Patent number: 11529363
    Abstract: Provided herein are methods for treating cancers (e.g., inflammatory myofibroblastic tumor, anaplastic large cell lymphoma, and neuroblastoma) in pediatric patients using brigatinib, as monotherapy or combination therapy with one or more second therapeutic agents.
    Type: Grant
    Filed: March 18, 2019
    Date of Patent: December 20, 2022
    Inventors: Sharon Bowen, Michael Hanley, David Kerstein, Karthik Venkatakrishnan
  • Methods for cancer therapy
    Patent number: 11241448
    Abstract: The present disclosure relates to methods or dosing regimens comprising a proteasome inhibitor of formula (I), or a pharmaceutically acceptable salt thereof, for treating cancer, or preventing cancer recurrence or progression; wherein ring A, Z1 and Z2 are as defined herein.
    Type: Grant
    Filed: March 1, 2021
    Date of Patent: February 8, 2022
    Assignee: Millennium Pharmaceuticals, Inc.
    Inventors: Ai-Min Hui, Richard Labotka, Neeraj Gupta, Karthik Venkatakrishnan, Guohui Liu
  • METHODS FOR CANCER THERAPY
    Publication number: 20210177871
    Abstract: The present disclosure relates to methods or dosing regimens comprising a proteasome inhibitor of formula (I), or a pharmaceutically acceptable salt thereof, for treating cancer, or preventing cancer recurrence or progression; wherein ring A, Z1 and Z2 are as defined herein.
    Type: Application
    Filed: March 1, 2021
    Publication date: June 17, 2021
    Inventors: Ai-Min Hui, Richard Labotka, Neeraj Gupta, Karthik Venkatakrishnan, Guohui Liu
  • METHODS OF TREATING CANCER IN PEDIATRIC PATIENTS
    Publication number: 20210000845
    Abstract: Provided herein are methods for treating cancers (e.g., inflammatory myofibroblastic tumor, anaplastic large cell lymphoma, and neuroblastoma) in pediatric patients using brigatinib, as monotherapy or combination therapy with one or more second therapeutic agents.
    Type: Application
    Filed: March 18, 2019
    Publication date: January 7, 2021
    Inventors: Sharon Bowen, Michael Hanley, David Kerstein, Karthik Venkatakrishnan
  • Methods for Cancer Therapy
    Publication number: 20200171061
    Abstract: The present disclosure relates to methods or dosing regimens comprising a proteasome inhibitor of formula (I), or a pharmaceutically acceptable salt thereof, for treating cancer, or preventing cancer recurrence or progression; wherein ring A, Z1 and Z2 are as defined herein.
    Type: Application
    Filed: February 4, 2020
    Publication date: June 4, 2020
    Inventors: Ai-Min Hui, Richard Labotka, Neeraj Gupta, Karthik Venkatakrishnan, Guohui Liu
  • METHODS FOR CANCER THERAPY
    Publication number: 20190343851
    Abstract: The present disclosure relates to methods or dosing regimens comprising a proteasome inhibitor of formula (I), or a pharmaceutically acceptable salt thereof, for treating cancer, or preventing cancer recurrence or progression; wherein ring A, Z1 and Z2 are as defined herein.
    Type: Application
    Filed: July 22, 2019
    Publication date: November 14, 2019
    Inventors: AI-MIN HUI, Richard Labotka, Neeraj Gupta, Karthik Venkatakrishnan, Guohui Liu
  • METHODS FOR CANCER THERAPY
    Publication number: 20190125773
    Abstract: The present disclosure relates to methods or dosing regimens comprising a proteasome inhibitor of formula (I), or a pharmaceutically acceptable salt thereof, for treating cancer, or preventing cancer recurrence or progression; wherein ring A, Z1 and Z2 are as defined herein.
    Type: Application
    Filed: December 21, 2018
    Publication date: May 2, 2019
    Inventors: AI-MIN HUI, Richard Labotka, Neeraj Gupta, Karthik Venkatakrishnan, Guohui Liu
  • Methods of treating cancer using aurora kinase inhibitors
    Patent number: 10213436
    Abstract: Disclosed are methods for the treatment of various cell proliferative disorders. Disclosed in particular are methods for treatment of various cell proliferative disorders by administering a selective inhibitor of Aurora A kinase in combination with taxane-based chemotherapy, such as paclitaxel or docetaxel.
    Type: Grant
    Filed: September 3, 2015
    Date of Patent: February 26, 2019
    Assignee: Millennium Pharmaceuticals, Inc.
    Inventors: Jeffrey A. Ecsedy, Wen Chyi Shyu, Arijit Chakravarty, Robert W. Kleinfield, Kha N. Le, Karthik Venkatakrishnan
  • METHODS OF TREATING CANCER USING AURORA KINASE INHIBITORS
    Publication number: 20160193224
    Abstract: Disclosed are methods for the treatment of various cell proliferative disorders. Disclosed in particular are methods for treatment of various cell proliferative disorders by administering a selective inhibitor of Aurora A kinase in combination with taxane-based chemotherapy, such as paclitaxel or docetaxel.
    Type: Application
    Filed: September 3, 2015
    Publication date: July 7, 2016
    Inventors: Jeffrey A. Ecsedy, Wen Chyi Shyu, Arijit Chakravarty, Robert W. Kleinfield, Kha N. Le, Karthik Venkatakrishnan
  • METHOD FOR CANCER THERAPY
    Publication number: 20150335668
    Abstract: The present disclosure relates to methods or dosing regimens comprising a proteasome inhibitor of formula (I), or a pharmaceutically acceptable salt thereof, for treating cancer, or preventing cancer recurrence or progression; wherein ring A, Z1 and Z2 are as defined herein.
    Type: Application
    Filed: May 19, 2015
    Publication date: November 26, 2015
    Inventors: AI-MIN HUI, Richard Labotka, Neeraj Gupta, Karthik Venkatakrishnan, Guohui Lui