Abstract: Systems and methods are provided for evaluating a stability of a joint within the foot and ankle complex of a subject. The subject is instructed to assume a position in which the joint is bearing weight, and a three-dimensional medical image of the joint comprising a sequence of two-dimensional image slices is captured at a scanner. The sequence of two-dimensional image slices is provided to a predictive model, comprising an artificial neural network having at least one convolutional layer. A clinical parameter representing the stability of the joint at the predictive model is determined from at least the sequence of two-dimensional image slices.

Abstract: Systems and methods are provided for determining a clinical parameter via evaluation of sequential medical images. A sequence of at least three medical images for a patient are captured at a scanner. A set of at least two difference images are generated from the sequence of at least three medical images. Each difference image represents a difference in content between two adjacent images in the sequence of at least three medical images. The set of at least two difference images are provided to a predictive model. The predictive model includes an artificial neural network having at least one convolutional layer. A clinical parameter for the patient is determined at the predictive model from at least the set of at least two difference images.

Abstract: A system for determining conditions within or near an implant apparatus in region of a subject includes an implant apparatus configured to be piezoresistive, the implant apparatus positioned in a region of a subject having a surface, and an electrical impedance tomography system. The electrical impedance tomography system includes a plurality of electrodes disposed on the surface of the region of the subject, each of the plurality of electrodes configured to apply a current to the region of the subject and to receive measurement signals from the region of the subject in response to an applied current.

Abstract: A wound closure device is provided. The wound closure device includes a first pad with an adhesive surface and a second pad with an adhesive surface. The wound closure device also includes a first tension adjusting pad with a first section, a first connecting element and a second connecting element. The first tension adjust pad is configured to move the first pad towards the second pad when the first tension adjusting pad is moved away from the first pad. The wound closure device also includes a second tension adjusting pad with a second section, a third connecting element and fourth connecting element. The second tension adjusting pad is configured to move the second pad towards the first pad when the second tension adjusting pad is moved away from the second pad. The wound closure device further includes a first cross bar for securing the first and third connecting elements.

Abstract: A method of manufacturing at least one component of a joint prosthesis, the method comprising creating a first database representing an anatomy of an articulating bone of a joint of a subject; accessing a second database representing a geometry of a generic prosthetic component being sized to fit around an outer articulating surface of the articulating bone of the joint of the subject; creating a third database representing kinematic data of the subject's joint; merging the databases within a three-dimensional image-based medium. The generic prosthetic component is attached to the outer articulating surface of the articulating bone of the joint creating a prosthetic articulating surface that is moved through the kinematic data of the subject through a bearing template thereby modifying the bearing template to create a kinematically appropriate bearing surface; and manufacturing the component of the joint prosthesis to have a geometry corresponding to the kinematically appropriate bearing surface.

Abstract: Femoral heads, mobile inserts, acetabular components, and modular junctions for orthopedic implants, e.g., hip replacement implants, and methods of using femoral heads, mobile inserts, acetabular components, and modular junctions for orthopedic implants are provided. Prosthetic femoral heads, mobile inserts, and acetabular components are provided that can alleviate soft tissue impingement, reduce implant wear, and/or reduce frictional torque. Modular junctions are provided that can minimize the incidence of loosening and micromotion that can occur at modular junctions of orthopedic implants.

Abstract: The present invention provides a femoral prosthesis for a femur which can enable or allow deep knee flexion without creating excessive tension in the ligamentous structure of the knee. The femoral prosthesis includes an internal non-articulating surface, an external articulating surface, a medial condyle and a lateral condyle. The height of the medial condyle is less than the height of the lateral condyle. A proximal-posterior tip of the medial condyle is rounded and is shifted inwards relative to the native level of the proximal-posterior region of the femur bone to facilitate knee flexion. A method of mounting a femoral prosthesis on a femur is also described.

Abstract: The present invention relates to cruciate ligament retaining knee implants, and instruments and methods for implanting cruciate ligament retaining knee implants.

Abstract: The present invention provides a femoral prosthesis for a femur which can enable or allow deep knee flexion without creating excessive tension in the ligamentous structure of the knee. The femoral prosthesis includes an internal non-articulating surface, an external articulating surface, a medial condyle and a lateral condyle. The height of the medial condyle is less than the height of the lateral condyle. A proximal-posterior tip of the medial condyle is rounded and is shifted inwards relative to the native level of the proximal-posterior region of the femur bone to facilitate knee flexion. A method of mounting a femoral prosthesis on a femur is also described.

Abstract: Methods and devices are provided for knee joint replacement with anterior cruciate ligament (ACL) substitution. Generally, the methods and devices can allow a knee joint to be partially or totally replaced in conjunction with substitution of the knee joint's ACL. In one embodiment, a knee replacement prosthesis can include a medial or lateral femoral implant, a femoral intercondylar notch structure, a medial or lateral tibial insert, and an ACL-substitution member. The ACL-substitution member can be configured to engage with the femoral intercondylar notch structure during a full range of knee motion and/or during only early knee flexion.

Abstract: Methods and devices are provided for knee joint replacement with anterior cruciate ligament (ACL) substitution. Generally, the methods and devices can allow a knee joint to be partially or totally replaced in conjunction with substitution of the knee joint's ACL. In one embodiment, a knee replacement prosthesis can include a medial or lateral femoral implant, a femoral intercondylar notch structure, a medial or lateral tibial insert, and an ACL-substitution member. The ACL-substitution member can be configured to engage with the femoral intercondylar notch structure during a full range of knee motion and/or during only early knee flexion.

Abstract: Femoral heads, mobile inserts, acetabular components, and modular junctions for orthopedic implants, e.g., hip replacement implants, and methods of using femoral heads, mobile inserts, acetabular components, and modular junctions for orthopedic implants are provided. Prosthetic femoral heads, mobile inserts, and acetabular components are provided that can alleviate soft tissue impingement, reduce implant wear, and/or reduce frictional torque. Modular junctions are provided that can minimize the incidence of loosening and micromotion that can occur at modular junctions of orthopedic implants.

Abstract: Femoral heads, mobile inserts, acetabular components, and modular junctions for orthopedic implants, e.g., hip replacement implants, and methods of using femoral heads, mobile inserts, acetabular components, and modular junctions for orthopedic implants are provided. Prosthetic femoral heads, mobile inserts, and acetabular components are provided that can alleviate soft tissue impingement, reduce implant wear, and/or reduce frictional torque. Modular junctions are provided that can minimize the incidence of loosening and micromotion that can occur at modular junctions of orthopedic implants.

Abstract: Embodiments of the invention provide knee prostheses which more faithfully and closely replicate the function, anatomy and physiology of the normal human knee yielding a number of advantages. Among other things, such prostheses can provide an increased range of motion and function more normally particularly in extension, deep flexion and during normal gait. Knee prostheses according to various aspects of the invention recognize that during movement of the knee, particularly during flexion, the kinematics of the bones of the knee are a result of achieving equilibrium of the forces that cause motion of the knee. In addition, the shape of the articular surfaces acting in combination with forces imposed by various muscles, ligaments and tendons, determines the direction of the large contact forces.

Abstract: The present invention provides a femoral prosthesis for a femur which can enable or allow deep knee flexion without creating excessive tension in the ligamentous structure of the knee. The femoral prosthesis includes an internal non-articulating surface, an external articulating surface, a medial condyle and a lateral condyle. The height of the medial condyle is less than the height of the lateral condyle. A proximal-posterior tip of the medial condyle is rounded and is shifted inwards relative to the native level of the proximal-posterior region of the femur bone to facilitate knee flexion. A method of mounting a femoral prosthesis on a femur is also described.

Abstract: The present invention provides a femoral prosthesis for a femur which can enable or allow deep knee flexion without creating excessive tension in the ligamentous structure of the knee. The femoral prosthesis includes an internal non-articulating surface, an external articulating surface, a medial condyle and a lateral condyle. The height of the medial condyle is less than the height of the lateral condyle. A proximal-posterior tip of the medial condyle is rounded and is shifted inwards relative to the native level of the proximal-posterior region of the femur bone to facilitate knee flexion. A method of mounting a femoral prosthesis on a femur is also described.

Abstract: Methods and devices are provided for knee joint replacement with anterior cruciate ligament (ACL) substitution. Generally, the methods and devices can allow a knee joint to be partially or totally replaced in conjunction with substitution of the knee joint's ACL. In one embodiment, a knee replacement prosthesis can include a medial or lateral femoral implant, a femoral intercondylar notch structure, a medial or lateral tibial insert, and an ACL-substitution member. The ACL-substitution member can be configured to engage with the femoral intercondylar notch structure during a full range of knee motion and/or during only early knee flexion.