Patents by Inventor Katherine E. Bujold

Katherine E. Bujold has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11896943
    Abstract: Methods of stabilizing DNA-engineered crystals can include cross-linking the hybridized oligonucleotides. Stabilized crystals can have improved chemical and thermal stability.
    Type: Grant
    Filed: May 22, 2020
    Date of Patent: February 13, 2024
    Assignee: NORTHWESTERN UNIVERSITY
    Inventors: Chad A. Mirkin, Seungkyu Lee, Cindy Yizhe Zheng, Katherine E. Bujold
  • Publication number: 20230382941
    Abstract: The present disclosure is directed to spherical nucleic acids (SNAs) comprising a nanoparticle core and an oligonucleotide dendron attached thereto. The disclosure also provides methods of using the SNAs for, for example, gene regulation and immune regulation.
    Type: Application
    Filed: July 24, 2023
    Publication date: November 30, 2023
    Inventors: Chad A. Mirkin, Katherine E. Bujold, Max Everett Distler
  • Publication number: 20210122778
    Abstract: The present disclosure is directed to spherical nucleic acids (SNAs) comprising a nanoparticle core and an oligonucleotide dendron attached thereto. The disclosure also provides methods of using the SNAs for, for example, gene regulation and immune regulation.
    Type: Application
    Filed: October 21, 2020
    Publication date: April 29, 2021
    Inventors: Chad A. Mirkin, Katherine E. Bujold, Max E. Distler, Caroline Kusmierz
  • Publication number: 20200399304
    Abstract: Disclosed herein are spherical nucleic acids (SNAs) comprising oligonucleotides comprising one or more modified oligonucleotides, and methods of use thereof. Also disclosed are methods of synthesizing modified oligonucleotides for use in therapeutics, including deoxynucleic guanidine (DNG)-modified oligonucleotides.
    Type: Application
    Filed: June 19, 2020
    Publication date: December 24, 2020
    Inventors: Chad A. Mirkin, Kacper Skakuj, Katherine E. Bujold
  • Publication number: 20200368708
    Abstract: Methods of stabilizing DNA-engineered crystals can include cross-linking the hybridized oligonucleotides. Stabilized crystals can have improved chemical and thermal stability.
    Type: Application
    Filed: May 22, 2020
    Publication date: November 26, 2020
    Inventors: Chad A. Mirkin, Seungkyu Lee, Cindy Yizhe Zheng, Katherine E. Bujold