Abstract: System includes a target assembly having a production chamber. The target assembly includes an electrode and a conductive base exposed to the production chamber. The target assembly has fluidic ports that provide access to the production chamber. The system also includes a fluidic-control system having a storage vessel and fluidic lines that connect to the fluidic ports. The storage vessel and the production chamber are in flow communication through at least one of the fluidic lines. The system also includes a power source that is configured to be electrically connected to the electrode and the conductive base. The production chamber, the electrode, and the conductive base form an electrolytic cell when an electrolytic solution is disposed in the production chamber. The power source is configured to apply voltage to the electrode and the conductive base to deposit a solid target along conductive base.

Abstract: This disclosure relates to methods for purifying and isolating astatine-211 from bismuth metal. Also disclosed are automated methods for purifying and isolating astatine-211 from bismuth metal.

Abstract: Recycling of isotopically enriched molybdenum metal targets that are suitable for the large scale cyclotron production of 99mTc or 94mTc includes the charged particle irradiation of an enriched molybdenum metal target to produce a technetium isotope, separation of the technetium isotope following irradiation of the molybdenum, re-claiming the molybdenum metal and reformation of the molybdenum target for a further irradiation step. This process may then be repeated. Separation of the technetium isotope preferably is achieved by oxidative dissolution of the molybdenum thereby removing it from a target support plate, and forming molybdate and pertechnetate. The technetium isotope is isolated by various means, such as the ABEC process. To reuse the molybdenum, additional steps of isolating the molybdate and reducing it back to molybdenum metal are required.