Patents by Inventor Katherine Whartenby

Katherine Whartenby has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Modulation of systemic immune responses by transplantation of hematopoietic stem cells transduced with genes encoding antigens and antigen presenting cell regulatory molecules
    Patent number: 7767202
    Abstract: The invention provides methods and compositions for the modulation of systemic immune responses by transplantation of hematopoietic stem cells transduced with genes encoding antigens and antigen presenting cell regulatory molecules. The invention includes bi-cistronic lentiviral expression vectors adapted for antigen expression in antigen presenting cells for use in DNA vaccines directed against pathogens and tumor antigens as well as for the treatment of autoimmune disease and for the establishment of antigen tolerance.
    Type: Grant
    Filed: March 18, 2002
    Date of Patent: August 3, 2010
    Assignee: The Johns Hopkins University
    Inventors: Drew M. Pardoll, Linzhao Cheng, Yan Cui, Curt I Civin, Katherine Whartenby
  • Modulation of systemic immune responses by transplantation of hematopoietic stem cells transduced with genes encoding antigens and antigen presenting cell regulatory molecules
    Publication number: 20040142468
    Abstract: The invention provides methods and compositions for the modulation of systemic immune responses by transplantation of hematopoietic stem cells transduced with genes encoding antigens and antigen presenting cell regulatory molecules. The invention includes bi-cistronic lentiviral expression vectors adapted for antigen expression in antigen presenting cells for use in DNA vaccines directed against pathogens and tumor antigens as well as for the treatment of autoimmune disease and for the establishment of antigen tolerance.
    Type: Application
    Filed: March 18, 2004
    Publication date: July 22, 2004
    Inventors: Drew M Pardoll, Linzhao Cheng, Yan Cui, Curt I Civin, Katherine Whartenby
  • Fas ligand expressing hematopoietic cells for transplantation
    Publication number: 20040131599
    Abstract: The invention provides methods and compositions utilizing FasL armed donor graft cells to reduce or eliminate host allogeneic or xenogeneic graft rejection, and FasL armed host cells to reduce or eliminate graft versus host disease.
    Type: Application
    Filed: February 25, 2004
    Publication date: July 8, 2004
    Inventors: Curt I Civin, Daniel Drachman, Katherine Whartenby, Drew M Pardoll