Patents by Inventor Kathleen A. Prodan

Kathleen A. Prodan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for antiarrhythmic 1,3-diazabicyclo[4.4.0]dec-2-en-4-ones
    Patent number: 4791199
    Abstract: This invention relates to a process for preparing useful antiarrhythmic 1,3-diazabicyclo[4.4.0]dec-2-en-4-ones from 1-acyl-.alpha.-[2-[bis(1-methylethyl)amino]ethyl]-.alpha.-phenyl-2-piperid ineacetamides. This invention also relates to the 1-acyl-.alpha.-[2-[bis(1-methylethyl)amino]ethyl]-.alpha.-phenyl-2-piperid ineacetamides employed in this process.
    Type: Grant
    Filed: September 19, 1985
    Date of Patent: December 13, 1988
    Assignee: G. D. Searle & Co.
    Inventors: Kathleen T. McLaughlin, Robert J. Chorvat, Kathleen A. Prodan
  • Hexahydroindolizinones useful for treating cardiac arrhythmia, thrombotic disorders in mammals
    Patent number: 4567270
    Abstract: This invention relates to hexahydroindolizinones, which are useful as inhibitors of cardiac arrhythmias and of platelet aggregation and are therefore useful in the treatment of irregular heartbeat and in the prevention of thrombus formation.
    Type: Grant
    Filed: September 17, 1984
    Date of Patent: January 28, 1986
    Assignee: G. D. Searle & Co.
    Inventors: Robert J. Chorvat, Kathleen A. Prodan, John A. Schulz
  • 8-Aryl-1,2,3,4-tetrahydroisoquinoline and derivatives thereof
    Patent number: 4220778
    Abstract: 8-Aryl-1,2,3,4-tetrahydroisoquinoline and derivatives thereof having the formula ##STR1## and the non-toxic pharmacologically acceptable acid addition salts thereof; wherein R is hydrogen, benzyl, or an alkyl radical of 1 to 7 carbon atoms; R.sup.1 is hydrogen or an alkyl radical of 1 to 7 carbon atoms; R.sup.2 in each occurrence is hydrogen, an alkyl radical of 1 to 7 carbon atoms or alkoxy radical of 1 to 7 carbon atoms, alike or different; Ar is phenyl optionally substituted with one or more halogen, an alkyl radical of 1 to 7 carbon atoms, or alkoxy radical of 1 to 7 carbon atoms; and n is positive integer less than 4, are disclosed. These compounds are useful because of their anti-arrhythmic, antimicrobial and central nervous system activity.
    Type: Grant
    Filed: October 30, 1978
    Date of Patent: September 2, 1980
    Assignee: G. D. Searle & Co.
    Inventors: Charles R. Ellefson, Kathleen Prodan