Patents by Inventor Kathrin Schwager

Kathrin Schwager has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ANTIGEN ASSOCIATED WITH RHEUMATOID ARTHRITIS
    Publication number: 20190352384
    Abstract: The invention relates to a binding member that binds the Extra Domain-A (ED-A) isoform of fibronectin for the detection and treatment of rheumatoid arthritis.
    Type: Application
    Filed: July 17, 2019
    Publication date: November 21, 2019
    Inventors: Manuela Kaspar, Kathrin Schwager, Eveline Trachsel
  • Antigen associated with rheumatoid arthritis
    Patent number: 10385121
    Abstract: The invention relates to a binding member that binds the Extra Domain-A (ED-A) isoform of fibronectin for the detection and treatment of rheumatoid arthritis.
    Type: Grant
    Filed: December 15, 2016
    Date of Patent: August 20, 2019
    Assignee: PHILOGEN S.P.A.
    Inventors: Manuela Kaspar, Kathrin Schwager, Eveline Trachsel
  • Anti-ED-A immunoconjugates for inflammatory bowel disease
    Patent number: 10239939
    Abstract: Specific binding members that bind the ED-A isoform of fibronectin for use in methods of treatment, diagnosis, detection and/or imaging of inflammatory bowel disease (IBD), and/or for use in delivery to the IBD tissue of a molecule conjugated to the specific binding member. The specific binding member may, for example, be conjugated to an immunosupressive or anti-inflammatory molecule, such as interleukin-10.
    Type: Grant
    Filed: June 1, 2017
    Date of Patent: March 26, 2019
    Assignee: PHILOGEN S.P.A.
    Inventors: Giovanni Neri, Kathrin Schwager, Melanie C. Ruzek, Denise M. O'hara, Jianqing Chen
  • Immunocytokine combination therapy
    Patent number: 10195253
    Abstract: Methods and compositions for treating tumors, especially skin tumors, by locally administering single doses of tumor necrosis factor alpha (TNF?) and interleukin-2 (IL2) at the tumor site, where the TNF? and IL2 are delivered as immunoconjugates comprising an antibody targeted to a splice isoform of an extracellular matrix component such as fibronectin.
    Type: Grant
    Filed: June 29, 2012
    Date of Patent: February 5, 2019
    Assignee: PHILOGEN S.P.A.
    Inventor: Kathrin Schwager
  • Antigens associated with endometriosis, psoriatic arthritis and psoriasis
    Patent number: 10112992
    Abstract: Specific binding members that bind the ED-A isoform of fibronectin for use in methods of diagnosis, detection, imaging and/or treatment of endometriosis, and/or for use in delivery to the neovasculature of endometriotic tissue of a molecule conjugated to the specific binding member. Specific binding members that bind tenascin-C, especially the A1, A2, A3, A4 and/or D domain tenascin-C large isoform, for use in methods of diagnosis, detection, imaging and/or treatment of endometriosis, psoriatic arthritis or psoriasis, and/or for use in delivery to the neovasculature of endometriotic, psoriatic arthritic or psoriatic tissue of a molecule conjugated to the specific binding member.
    Type: Grant
    Filed: November 22, 2016
    Date of Patent: October 30, 2018
    Assignee: Philogen S.P.A.
    Inventor: Kathrin Schwager
  • ANTIGENS ASSOCIATED WITH INFLAMMATORY BOWEL DISEASE
    Publication number: 20180044408
    Abstract: Specific binding members that bind the ED-A isoform of fibronectin for use in methods of treatment, diagnosis, detection and/or imaging of inflammatory bowel disease (IBD), and/or for use in delivery to the IBD tissue of a molecule conjugated to the specific binding member. The specific binding member may, for example, be conjugated to an immunosupressive or anti-inflammatory molecule, such as interleukin-10.
    Type: Application
    Filed: June 1, 2017
    Publication date: February 15, 2018
    Inventors: Giovanni Neri, Kathrin Schwager, Melanie C. Ruzek, Denise M. O'hara, Jianqing Chen
  • ANTIGEN ASSOCIATED WITH RHEUMATOID ARTHRITIS
    Publication number: 20170298122
    Abstract: The invention relates to a binding member that binds the Extra Domain-A (ED-A) isoform of fibronectin for the detection and treatment of rheumatoid arthritis.
    Type: Application
    Filed: December 15, 2016
    Publication date: October 19, 2017
    Inventors: Manuela Kaspar, Kathrin Schwager, Eveline Trachsel
  • Anti-ED-A immunoconjugates for inflammatory bowel disease
    Patent number: 9695232
    Abstract: Specific binding members that bind the ED-A isoform of fibronectin for use in methods of treatment, diagnosis, detection and/or imaging of inflammatory bowel disease (IBD), and/or for use in delivery to the IBD tissue of a molecule conjugated to the specific binding member. The specific binding member may, for example, be conjugated to an immunosupressive or anti-inflammatory molecule, such as interleukin-10.
    Type: Grant
    Filed: October 3, 2012
    Date of Patent: July 4, 2017
    Assignee: Philogen S.p.A.
    Inventors: Giovanni Neri, Kathrin Schwager, Melanie C. Ruzek, Denise M. O'Hara, Jianqing Chen
  • ANTIGENS ASSOCIATED WITH ENDOMETRIOSIS, PSORIATIC ARTHRITIS AND PSORIASIS
    Publication number: 20170183398
    Abstract: Specific binding members that bind the ED-A isoform of fibronectin for use in methods of diagnosis, detection, imaging and/or treatment of endometriosis, and/or for use in delivery to the neovasculature of endometriotic tissue of a molecule conjugated to the specific binding member. Specific binding members that bind tenascin-C, especially the A1, A2, A3, A4 and/or D domain tenascin-C large isoform, for use in methods of diagnosis, detection, imaging and/or treatment of endometriosis, psoriatic arthritis or psoriasis, and/or for use in delivery to the neovasculature of endometriotic, psoriatic arthritic or psoriatic tissue of a molecule conjugated to the specific binding member.
    Type: Application
    Filed: November 22, 2016
    Publication date: June 29, 2017
    Inventor: Kathrin Schwager
  • Antigen associated with rheumatoid arthritis
    Patent number: 9556257
    Abstract: The invention relates to a binding member that binds the Extra Domain-A (ED-A) isoform of fibronectin for the detection and treatment of rheumatoid arthritis.
    Type: Grant
    Filed: June 5, 2012
    Date of Patent: January 31, 2017
    Assignee: PHILOGEN S.P.A.
    Inventors: Manuela Kaspar, Kathrin Schwager, Eveline Trachsel
  • Sequential antibody therapy
    Patent number: 9549981
    Abstract: The invention provides a blocking ligand specific for CTLA-4 and a vascular targeting ligand/IL-2 complex, for sequential use in inhibiting the growth of tumor cell.
    Type: Grant
    Filed: June 22, 2012
    Date of Patent: January 24, 2017
    Assignee: Philogen S.p.A.
    Inventor: Kathrin Schwager
  • Antigens associated with endometriosis, psoriatic arthritis and psoriasis
    Patent number: 9527907
    Abstract: Specific binding members that bind the ED-A isoform of fibronectin for use in methods of diagnosis, detection, imaging and/or treatment of endometriosis, and/or for use in delivery to the neovasculature of endometriotic tissue of a molecule conjugated to the specific binding member. Specific binding members that bind tenascin-C, especially the A1, A2, A3, A4 and/or D domain tenascin-C large isoform, for use in methods of diagnosis, detection, imaging and/or treatment of endometriosis, psoriatic arthritis or psoriasis, and/or for use in delivery to the neovasculature of endometriotic, psoriatic arthritic or psoriatic tissue of a molecule conjugated to the specific binding member.
    Type: Grant
    Filed: December 28, 2009
    Date of Patent: December 27, 2016
    Assignee: Philogen S.P.A.
    Inventor: Kathrin Schwager
  • ANTIGENS ASSOCIATED WITH INFLAMMATORY BOWEL DISEASE
    Publication number: 20150361161
    Abstract: Specific binding members that bind the ED-A isoform of fibronectin for use in methods of treatment, diagnosis, detection and/or imaging of inflammatory bowel disease (IBD), and/or for use in delivery to the IBD tissue of a molecule conjugated to the specific binding member. The specific binding member may, for example, be conjugated to an immunosupressive or anti-inflammatory molecule, such as interleukin-10.
    Type: Application
    Filed: October 3, 2012
    Publication date: December 17, 2015
    Inventors: Giovanni Neri, Kathrin Schwager, Melanie C. Ruzek, Denise M. O'Hara, Jianqing Chen
  • SEQUENTIAL ANTIBODY THERAPY
    Publication number: 20140193908
    Abstract: The invention provides a blocking ligand specific for CTLA-4 and a vascular targeting ligand/IL-2 complex, for sequential use in inhibiting the growth of tumour cell
    Type: Application
    Filed: June 22, 2012
    Publication date: July 10, 2014
    Applicant: Philogen S.p.A.
    Inventor: Kathrin Schwager
  • Antigens Associated with Inflammatory Bowel Disease Including Ulcerative Colitis
    Publication number: 20120251439
    Abstract: Specific binding members that bind the ED-A isoform of fibronectin for use in methods of diagnosis, detection, imaging and/or treatment of inflammatory bowel disease such as ulcerative colitis and/or for use in delivery to the neovasculature of intestinal tissue of a molecule conjugated to the specific binding member. Specific binding members that bind tenascin-C, especially the A1, A2, A3, A4 and/or D domain tenascin-C large isoform, for use in methods of diagnosis, detection, imaging and/or treatment of ulcerative colitis and/or for use in delivery to the neovasculature of inflammatory bowel disease tissue of a molecule conjugated to the specific binding member.
    Type: Application
    Filed: May 16, 2012
    Publication date: October 4, 2012
    Inventor: Kathrin Schwager
  • ANTIGEN ASSOCIATED WITH RHEUMATOID ARTHRITIS
    Publication number: 20120244114
    Abstract: The invention relates to a binding member that binds the Extra Domain-A (ED-A) isoform of fibronectin for the detection and treatment of rheumatoid arthritis.
    Type: Application
    Filed: June 5, 2012
    Publication date: September 27, 2012
    Inventors: Manuela Kaspar, Kathrin Schwager, Eveline Trachsel
  • Antigen associated with rheumatoid arthritis
    Patent number: 8222377
    Abstract: The invention relates to a binding member that binds the Extra Domain-A (ED-A) isoform of fibronectin for the detection and treatment of rheumatoid arthritis.
    Type: Grant
    Filed: October 27, 2008
    Date of Patent: July 17, 2012
    Assignee: Philogen, S.p.A.
    Inventors: Manuela Kaspar, Kathrin Schwager, Eveline Trachsel
  • Cancer Treatment
    Publication number: 20110318302
    Abstract: The invention relates to the treatment of cancer, e.g. kidney cancer, using chemotherapeutic agents and immunocytokines, in particular immunocytokines which bind to the Extra Domain-A (ED-A) isoform of fibronectin.
    Type: Application
    Filed: December 23, 2009
    Publication date: December 29, 2011
    Inventors: Kathrin Schwager, Katharina Frey, Christoph Schliemann, Neri Dario
  • Antigens Associated with Endometriosis, Psoriatic Arthritis and Psoriasis
    Publication number: 20110250131
    Abstract: Specific binding members that bind the ED-A isoform of fibronectin for use in methods of diagnosis, detection, imaging and/or treatment of endometriosis, and/or for use in delivery to the neovasculature of endometriotic tissue of a molecule conjugated to the specific binding member. Specific binding members that bind tenascin-C, especially the A1, A2, A3, A4 and/or D domain tenascin-C large isoform, for use in methods of diagnosis, detection, imaging and/or treatment of endometriosis, psoriatic arthritis or psoriasis, and/or for use in delivery to the neovasculature of endometriotic, psoriatic arthritic or psoriatic tissue of a molecule conjugated to the specific binding member.
    Type: Application
    Filed: December 28, 2009
    Publication date: October 13, 2011
    Applicant: Philogen S.P.A.
    Inventor: Kathrin Schwager
  • ANTIGEN ASSOCIATED WITH RHEUMATOID ARTHRITIS
    Publication number: 20100260707
    Abstract: The invention relates to a binding member that binds the Extra Domain-A (ED-A) isoform of fibronectin for the detection and treatment of rheumatoid arthritis.
    Type: Application
    Filed: October 27, 2008
    Publication date: October 14, 2010
    Applicant: PHILOGEN S.P.A.
    Inventors: Manuela Kaspar, Kathrin Schwager, Eveline Trachsel