Patents by Inventor Kathryn Mason Lindley

Kathryn Mason Lindley has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • MYOSTATIN BINDING PROTEINS
    Publication number: 20110256132
    Abstract: Description of antigen binding proteins, such as antibodies, which bind to myostatin, polynucleotides encoding such antigen binding proteins, pharmaceutical compositions comprising said antigen binding proteins and methods of manufacture. Furthermore, description of the use of such antigen binding proteins in the treatment or prophylaxis of diseases associated with anyone or a combination of decreased muscle mass, muscle strength and muscle function.
    Type: Application
    Filed: December 18, 2009
    Publication date: October 20, 2011
    Inventors: Claire Ashman, Andrew Beaton, Jonathan Henry Ellis, Baijin Han, Ian Kirby, Frederick Kull, Alan Lewis, Kathryn Mason Lindley, Martin Anibal Orecchia, Ying Shen, Paul Wilson, Tian Shun Xun, Hong Zhang
  • Superficial zone protein-binding molecules and uses thereof
    Patent number: 6720156
    Abstract: The invention provides an antibody or a fragment thereof having specific binding affinity for superficial zone protein (SZP) or a variant, fragment, or protein core thereof, wherein the binding affinity of the antibody or fragment thereof for human superficial zone protein is the same or greater than the binding affinity for bovine superficial zone protein in a competitive binding assay, IAsys analysis, or BIAcore analysis. The present invention further provides hybidoma cells that produce the monoclonal antibody and antibody reagent kits comprising the antibody or fragment of the invention. Further provided by the invention are methods of SZP detection, methods of diagnosing a degenerative joint condition, and screening methods related to the use of the antibody or fragment thereof.
    Type: Grant
    Filed: February 9, 2001
    Date of Patent: April 13, 2004
    Assignees: SmithKline Beecham Corporation, Rush-Presbyterian St Luke's Medical Center
    Inventors: Jeff T. Hutchins, Klaus E. Kuettner, Kathryn Mason Lindley, Thomas M. Schmid, Barbara L. Schumacher, Stephen Anthony Stimpson, Jui-Lan Su
  • Superficial zone protein-binding molecules and uses thereof
    Publication number: 20020009761
    Abstract: The invention provides an antibody or a fragment thereof having specific binding affinity for superficial zone protein (SZP) or a variant, fragment, or protein core thereof, wherein the binding affinity of the antibody or fragment thereof for human superficial zone protein is the same or greater than the binding affinity for bovine superficial zone protein in a competitive binding assay, IAsys analysis, or BlAcore analysis. The present invention further provides hybidoma cells that produce the monoclonal antibody and antibody reagent kits comprising the antibody or fragment of the invention. Further provided by the invention are methods of SZP detection, methods of diagnosing a degenerative joint condition, and screening methods related to the use of the antibody or fragment thereof.
    Type: Application
    Filed: February 9, 2001
    Publication date: January 24, 2002
    Inventors: Jeff T. Hutchins, Klaus E. Kuettner, Kathryn Mason Lindley, Thomas M. Schmid, Barbara L. Schumacher, Stephen Anthony Stimpson, Jui-Lan Su