Abstract: Provided herein are IL-2 muteins, IL-2 mutein Fc-fusion molecules, anti-IL-2 antibodies, and complexes comprising an anti IL-2 antibody bound to an IL-2 cytokine that preferentially expand and activate T regulatory cells and are amenable to large scale production. Also provided herein are variant human IgG1 Fc molecules lacking or with highly reduced effector function and high stability despite lacking glycosylation at N297. Also provided herein are linker peptides that are glycosylated when expressed in mammalian cells. Also provided herein are methods of making and using the compositions of the present invention.

Abstract: Methods, systems, and apparatus, including computer programs encoded on a computer storage medium, for controlling a remotely operated vehicle (ROV) for performing an underwater task. One apparatus includes a watertight housing; a mounting hardware that attaches the watertight housing to the ROV; one or more sensors in the watertight housing, the one or more sensors configured to generate sensor data that is associated with an underwater task; and one or more processors in the watertight housing, the one or more processors configured to: receive the sensor data from the one or more sensors; generate a navigation plan for the ROV using the sensor data; determine, using the navigation plan, control instructions configured to control the ROV to perform the underwater task; and provide the control instructions to an interface of the ROV configured to communicate with the apparatus.

Abstract: Removable storage compartments are provided that can include a compartment housing formed to extend along sidewalls from a base portion and define an opening, a lid configured to couple with the housing and at least partially close the opening, with the lid not extending beyond the outermost portion of the sidewalls. Compartments can also have a least one mounting bracket recessed within at least one of the sidewalls. Methods of mounting a storage compartment to a snowmobile are provided that can include mounting a portion of a hasp to a portion of a snowmobile, providing a storage compartment having another portion of the hasp mounted thereto, and coupling the portions of the hasp to mount the compartment to the snowmobile, the coupled compartment having the hasp recessed below the compartment and within a perimeter define by the compartment. Ornamental designs for snowmobile accessories as shown in FIGS. 6-12.

Abstract: Removable storage compartments are provided that can include a compartment housing formed to extend along sidewalls from a base portion and define an opening, a lid configured to couple with the housing and at least partially close the opening, with the lid not extending beyond the outermost portion of the sidewalls. Compartments can also have a least one mounting bracket recessed within at least one of the sidewalls. Methods of mounting a storage compartment to a snowmobile are provided that can include mounting a portion of a hasp to a portion of a snowmobile, providing a storage compartment having another portion of the hasp mounted thereto, and coupling the portions of the hasp to mount the compartment to the snowmobile, the coupled compartment having the hasp recessed below the compartment and within a perimeter define by the compartment. Ornamental designs for snowmobile accessories as shown in FIGS. 6-12.

Abstract: The present invention provides improved electrochromic layers, which comprise polymeric matrices with electrochromic solutions interspersed therein. Varying an electrical potential difference across a layer of the invention results in reversible variation in the transmittance of light across the layer because of electrochemical processes in the electrochromic solution of the layer. The invention further provides electrochromic devices, in which the electrochromic layers of the invention provide reversibly variable transmittance to light, and various apparatus in which the devices of the invention provide light-filtering or light-color modulation. Such apparatus include windows, including those for use inside and on the outside walls of buildings and in sunroofs for automobiles, and variable reflectance mirrors, especially rearview mirrors for automobiles.

Abstract: The present invention is directed to an electrochemical medium for use in a reversible electrodeposition device including at least one solvent, at least one anodic electroactive material, at least one active metal; and optionally at least one redox buffer.

Abstract: An electrochromic medium for use in an electrochromic device comprising: at least one solvent; an anodic electroactive material; a cathodic electroactive material; wherein at least one of the anodic and cathodic electroactive materials is electrochromic; and a self-healing, cross-linked polymer matrix.

Abstract: The present invention is directed to a reversible electrodeposition device comprising: a first substrate having an electrically conductive material associated therewith; a second substrate having an electrically conductive material associated therewith; a nucleation layer at least partially covering at least one of the electrically conductive materials of the first and second substrates; an electrochemical medium contained within a chamber positioned between the first and second substrates.

Abstract: An electrochromic medium for use in an electrochromic device comprising: at least one solvent; an anodic electroactive material; a cathodic electroactive material, wherein at least one of the anodic and cathodic electroactive materials is electrochromic; and a current-reducing additive, wherein the current-reducing additive comprises a polymer present in an effective concentration to materially reduce the current of the electrochromic medium upon application of an electrical potential, relative to an electrochromic medium without the current-reducing additive, while maintaining an electrochromic medium viscosity which facilitates acceptable production rates without a problematic degree of seal or other device component failure.