Abstract: Provided is a nucleic acid purification method capable of efficiently purifying a nucleic acid. The nucleic acid purification method including the steps of: mixing a nucleic acid with an antifoaming agent and a coprecipitation agent; and purifying the nucleic acid, in which the antifoaming agent is at least one of a nonionic surfactant and a silicone antifoaming agent.

Abstract: Provided is an inspection chip with simplified channel switching structure, which is generally complicated.

Abstract: An object of the present invention is to provide a novel method for designing a primer ensuring reactivity and discriminatory power in a method for detecting a single base substitution based on an ASP-PCR method and to provide a method for easily detecting multiple point mutations within overlapping amplicons, particularly, two adjacent single base substitutions. The single base substitutions can easily be detected by using a mutant primer in which the base of the third nucleotide from the 3? end corresponds to the base of a mutant nucleotide of a single base substitution contained in a nucleic acid sample, in which the base of the second nucleotide from the 3? end is not complementary to the base of the corresponding nucleotide of the nucleic acid, and in which the bases of the other nucleotides are complementary to the bases of the corresponding nucleotides of the nucleic acid.

Abstract: Provided is a method for purifying a nucleic acid capable of easily purifying a nucleic acid and efficiently recovering the nucleic acid. The method for purifying a nucleic acid including a step of bringing a sample containing a nucleic acid into contact with an extraction solution containing a metal cation to prepare an extraction solution containing the nucleic acid, a step of bringing the extraction solution containing the nucleic acid into contact with an anionic adsorbent 4 to cause the nucleic acid to adsorb to the anionic adsorbent 4, a step of bringing a wash solution having a pH of 5.0 or less into contact with the anionic adsorbent 4 to wash the anionic adsorbent 4 to which the nucleic acid is adsorbed, and a step of bringing a recovery solution having a pH of 6.0 or more into contact with the anionic adsorbent 4 to isolate the nucleic acid from the anionic adsorbent 4.

Abstract: An inspection chip includes: a body part including a microchannel; and a liquid introduction part introducing liquid into the microchannel. The liquid introduction part includes: a liquid reception part; and a lid part capable of sealing the liquid reception part. The liquid reception part includes: a liquid storage part having an opening part in an upper part thereof; and a connection part connected to the microchannel from a bottom part of the liquid storage part. The lid part includes a protrusion part that protrudes so as to be housed in the liquid storage part.

Abstract: Provided is a nucleic acid isolation method whereby it becomes possible to extract a nucleic acid in a simple manner without the need to use an alcohol. A nucleic acid isolation method, comprising the steps of: mixing a specimen containing a nucleic acid with an extraction solution to disperse the nucleic acid in the extraction solution; bringing the extraction solution containing the nucleic acid into contact with an anionic adsorbent; bringing a washing solution into contact with the anionic adsorbent; and bringing a collection solution into contact with the anionic adsorbent, the extraction solution containing a protein denaturant, the washing solution containing a basic compound and having a pH value equal to or less than a pKa value of a conjugate acid of the basic compound, and the collection solution having a pH value equal to or more than the pKa value of the conjugate acid of the basic compound.

Abstract: An object of the present invention is to provide an efficient nucleic acid recovery method capable of concentrating a nucleic acid from a sample containing a nucleic acid such that the nucleic acid is usable in gene amplification reaction. To solve the problem, the present inventors have found that by targeting a protein to which a nucleic acid is bound (hereinafter also referred to as a nucleoprotein or a protein-nucleic acid complex) rather than targeting the nucleic acid itself, or specifically, by causing a specific antibody against the protein to act, the nucleic acid can be captured simultaneously with the protein, and thereby completing the present invention. Furthermore, the present inventors have found that if animal cells, bacteria, viruses, etc.

Abstract: An object of the present invention is to provide a method for accurately and quantitatively discriminating and detecting a wide variety of gene mutations, or particularly, single base substitutions or point mutations. In an ASP for analyzing gene mutations, or particularly, single base substitutions or point mutations, when a non-nucleotide component is added to the 5? end of at least one of the ASP and a primer paired therewith before amplification by PCR and amplification products thereof are separated by ion-exchange chromatography, even the amplification products having the same length can be separated and detected.

Abstract: An object of the present invention is to provide an efficient nucleic acid recovery method capable of concentrating a nucleic acid from a sample containing a nucleic acid such that the nucleic acid is usable in gene amplification reaction. To solve the problem, the present inventors have found that by targeting a protein to which a nucleic acid is bound (hereinafter also referred to as a nucleoprotein or a protein-nucleic acid complex) rather than targeting the nucleic acid itself, or specifically, by causing a specific antibody against the protein to act, the nucleic acid can be captured simultaneously with the protein, and thereby completing the present invention. Furthermore, the present inventors have found that if animal cells, bacteria, viruses, etc.

Abstract: An object of the present invention is to provide a method for accurately and quantitatively discriminating and detecting a wide variety of gene mutations, or particularly, single base substitutions or point mutations. In an ASP for analyzing gene mutations, or particularly, single base substitutions or point mutations, when a non-nucleotide component is added to the 5? end of at least one of the ASP and a primer paired therewith before amplification by PCR and amplification products thereof are separated by ion-exchange chromatography, even the amplification products having the same length can be separated and detected.

Abstract: An object of the present invention is to provide a novel method for designing a primer ensuring reactivity and discriminatory power in a method for detecting a single base substitution based on an ASP-PCR method and to provide a method for easily detecting multiple point mutations within overlapping amplicons, particularly, two adjacent single base substitutions. The single base substitutions can easily be detected by using a mutant primer in which the base of the third nucleotide from the 3? end corresponds to the base of a mutant nucleotide of a single base substitution contained in a nucleic acid sample, in which the base of the second nucleotide from the 3? end is not complementary to the base of the corresponding nucleotide of the nucleic acid, and in which the bases of the other nucleotides are complementary to the bases of the corresponding nucleotides of the nucleic acid.

Abstract: A projection device in which a displayed pointer image of an input device can be shifted by a plurality of users is provided. A projection device includes a wireless transmitting/receiving unit for receiving command signals of mouses connected with a plurality of computer units from the respective computer units; a pointer image generating unit (information processing unit) for generating pointer images of the mouses; a pointer image position setting unit (information processing unit) for setting a pointer image position based on the received command signals of the mouses; and a projection unit for projecting an image including the pointer image at least at the set position.

Abstract: In a stand-by condition, a distal end of a lock portion is received in a lock protective portion and it is not projected beyond a hood portion of a housing, and therefore the lock portion will not be broken during transport. When fixing the connector to a panel, pawls of the housing portion are inserted into a through hole in the panel, and are positioned relative thereto, and then the lock portion is slid, and therefore the lock portion will not accidentally strike against the panel, and hence will not be damaged.

Abstract: In a stand-by condition, a distal end of a lock portion is received in a lock protective portion and it is not projected beyond a hood portion of a housing, and therefore the lock portion will not be broken during transport. When fixing the connector to a panel, pawls of the housing portion are inserted into a through hole in the panel, and are positioned relative thereto, and then the lock portion is slid, and therefore the lock portion will not accidentally strike against the panel, and hence will not be damaged.