Abstract: The present invention relates to a medicament for treating or preventing central nervous system disease whose cause is related to abnormal aggregation of proteins in the brain, which comprises as an active ingredient a compound of formula (1) or a pharmaceutically acceptable salt thereof, wherein R1 and R2 are hydrogen, etc., R3 and R4 are hydrogen, C1-6 alkyl, etc., R5 is halogen, C1-6 alkyl, etc., R6 is hydrogen, halogen, etc., X is oxygen, etc., Y is carbon, etc., m and n are an integer of 0, 1, etc., r and s are 0, 1, 2, etc., Hy is pyridine ring, etc., which has an action of suppressing or reducing the accumulation of abnormal aggregation of proteins in the brain.

Abstract: A sample analyzer comprises an input to select a sample type to be measured from a plurality of platelet sample types of differing concentrations, a measurement part to obtain optical information of a sample, a processing part that calculates platelet aggregation information from the optical information, and an alarm part. The processing part determines whether the actual measured sample type differs from the inputted sample type based on the optical information from the measurement part, and actuates the alarm part accordingly.

Abstract: A sample analyzer comprises an input to select a sample type to be measured from a plurality of platelet sample types of differing concentrations, a measurement part to obtain optical information of a sample, a processing part that calculates platelet aggregation information from the optical information, and an alarm part. The processing part determines whether the actual measured sample type differs from the inputted sample type based on the optical information from the measurement part, and actuates the alarm part accordingly.

Abstract: The present invention relates to a reagent for the measurement of FDP comprising a carrier sensitized with at least two monoclonal antibodies selected from three monoclonal antibodies having different reactivity towards FDP. The present invention also relates to a reagent kit comprising the reagent and a method for measurement of FDP using the reagent or reagent kit.

Abstract: The present invention relates to an anti-FDP monoclonal antibody selected from the first, second and third monoclonal antibodies having different reactivity towards FDP. The present invention also relates to a reagent and reagent kit for the measurement of FDP and a method for measurement of FDP using the anti-FDP monoclonal antibodies.

Abstract: A platelet aggregation measuring method comprising: preparing a measurement sample which contains a sample and a reagent which includes a platelet activator; mixing the measurement sample at a first speed; mixing the measurement sample at a second speed which is greater than the first speed after mixing the sample at the first speed; obtaining optical information from the measurement sample while mixing the measurement sample at the second speed; and analyzing aggregation of platelets in the sample based on the optical information is disclosed. A platelet aggregation measuring apparatus is also disclosed.

Abstract: The present invention relates to an anti-FDP monoclonal antibody selected from the first, second and third monoclonal antibodies having different reactivity towards FDP. The present invention also relates to a reagent and reagent kit for the measurement of FDP and a method for measurement of FDP using the anti-FDP monoclonal antibodies.

Abstract: A sample analyzer includes (a) a measuring part for measuring optical information of a sample at first wavelength, second wavelength, and third wavelength, first light of the first wavelength and second light of the second wavelength being absorbed by a second substance but substantially not absorbed by a first substance, and third light of the third wavelength being absorbed by the first substance; and (b) an obtaining part for obtaining content of the first substance in the sample, and content of the second substance in the sample, influence by the second substance being excluded from the content of the first substance, based on the optical information at the first wavelength, second wavelength, and third wavelength measured by the measuring part.

Abstract: A reagent kit for measuring coagulation time is described herein. This reagent comprises calcium chelator which interferes with the reaction between calcium and substance other than a coagulation factor in a blood sample, and which substantially does not interfere with coagulation reaction. A method for measuring coagulation time is also described herein. The method comprises a contacting step and a measuring step. The contacting step is to contact a blood sample, calcium and compound selected from the group consisting of partial thromboplastin, tissue thromboplastin, and complex of tissue factor and phospholipid, in the presence of calcium chelator. This calcium chelator can interfere with the reaction between calcium and substance other than a coagulation factor in the blood sample and substantially does not interfere with coagulation reaction. The measuring step is to measure coagulation time of the blood sample.

Abstract: A platelet aggregation measuring method comprising: preparing a measurement sample which contains a sample and a reagent which includes a platelet activator; mixing the measurement sample at a first speed; mixing the measurement sample at a second speed which is greater than the first speed after mixing the sample at the first speed; obtaining optical information from the measurement sample while mixing the measurement sample at the second speed; and analyzing aggregation of platelets in the sample based on the optical information is disclosed. A platelet aggregation measuring apparatus is also disclosed.

Abstract: A sample analyzer comprising: a measuring part for measuring optical information of a sample at first wavelength, second wavelength, and third wavelength, first light of the first wavelength and second light of the second wavelength being absorbed by a second substance but substantially not absorbed by a first substance, and third light of the third wavelength being absorbed by the first substance; and an obtaining means for obtaining content of the first substance in the sample, and content of the second substance in the sample, influence by the second substance being excluded from the content of the first substance, based on the optical information at the first wavelength, second wavelength, and third wavelength measured by the measuring part.

Abstract: In the synchronous motor controlling apparatus and method of the invention, a current is detected and subjected to coordinate transformation onto &ggr;-&dgr; axis assumed for the rotor. A correction term is obtained on the basis of the derived current and an arbitrarily given correction current instruction. A &ggr;-&dgr; axis voltage instruction is computed by adding a value obtained by multiplying the correction term by a proper gain to a voltage equation in a steady state of the synchronous motor. Consequently, a control method of small computational load, which does not require gain adjustment according to the inertia of a motor load, can be attained.

Abstract: A conventional synchronous motor controlling method estimates the speed and performs a vector control, so that the gain of a speed control system has to be adjusted according to the inertia of a load connected to the motor shaft, and computation is also relatively complicated.

Abstract: A level marking apparatus capable of directly measuring height comprises an elastic synthetic resin tube. One end of the tube is secured to a pressure sensor capable of producing an output voltage and air-tightly sealed, and the other end of the tube is connected to a reference instrument, which has a larger diameter and is shorter in length than the tube. The tube is totally filled with low viscosity macromolecule liquid. Moreover, the pressure sensor is connected to a micro computer programmed to find an average value of fluctuation waveform within a certain cycle of output voltage of the pressure sensor. The micro computer also calculates and memorizes a reference level based on a pressure difference between the reference instrument and the pressure sensor when placed at different heights. Additionally, a marking device is connected to the pressure sensor, and it is actuated by an ON signal from the pressure sensor.