Patents by Inventor Katsutoshi Sakata

Katsutoshi Sakata has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7320973
    Abstract: The present invention provides dihydrodiaryloxazepine derivative represented by the following formula [1], analogs thereof and pharmaceutical compositions containing them.
    Type: Grant
    Filed: December 1, 2003
    Date of Patent: January 22, 2008
    Assignee: Ajinomoto Co., Inc.
    Inventors: Katsutoshi Sakata, Takashi Tsuji, Munetaka Tokumasu, Kazuyoshi Takahashi, Shigeo Hirasawa, Junko Ezaki
  • Publication number: 20040110742
    Abstract: The present invention provides dihydrodiaryloxazepine derivative represented by the following formula [1], analogs thereof and pharmaceutical compositions containing them. Those compounds have an excellent effect of improving functional diseases of gastrointestinal tracts.
    Type: Application
    Filed: December 1, 2003
    Publication date: June 10, 2004
    Applicant: Ajinomoto Co., Inc.
    Inventors: Katsutoshi Sakata, Takashi Tsuji, Munetaka Tokumasu, Kazuyoshi Takahashi, Shigeo Hirasawa, Junko Ezaki
  • Patent number: 6562808
    Abstract: 5,11-dihydrodibenzo[b,e][1,4]oxazepine derivatives of the following general formulae and analogs thereof have a calcium channel-antagonistic effect and they are effective in treating and preventing intestinal diseases such as abnormal motor function of digestive tracts, particularly, irritable bowel syndrome:
    Type: Grant
    Filed: March 10, 2000
    Date of Patent: May 13, 2003
    Assignee: Ajinomoto Co., Inc.
    Inventors: Katsutoshi Sakata, Takashi Tsuji, Noriko Sasaki, Kazuyoshi Takahashi
  • Patent number: 6528504
    Abstract: The present invention provides (R)-5,11-dihydro-5-[1-(4-methoxyphenethyl)piperidine-2-ylmethyl]dibenzo[b,e][1,4]oxazepine, (R)-5,11-dihydro-5-[1-(4-dimethylaminophenethyl)piperidine-2-ylmethyl]dibenzo[b,e][1,4]oxazepine, compounds analogous to them and pharmaceutical compositions containing such a compound. These compounds are useful for treating or preventing abnormal motor functions of gastrointestinal tracts, particularly irritable bowel syndrome.
    Type: Grant
    Filed: July 9, 2001
    Date of Patent: March 4, 2003
    Assignee: Ajinomoto Co., Inc.
    Inventors: Katsutoshi Sakata, Takashi Tsuji, Noriko Sasaki, Kazuyoshi Takahashi
  • Publication number: 20020099047
    Abstract: The present invention provides (R)-5,11-dihydro-5-[1-(4-methoxyphenethyl)piperidine-2-ylmethyl]dibenzo[b,e][1,4]oxazepine, (R)-5,11-dihydro-5-[1-(4-dimethylaminophenethyl)piperidine-2-ylmethyl]dibenzo[b,e][1,4]oxazepine, compounds analogous to them and pharmaceutical compositions containing such a compound. These compounds are useful for treating or preventing abnormal motor functions of gastrointestinal tracts, particularly irritable bowel syndrome.
    Type: Application
    Filed: July 9, 2001
    Publication date: July 25, 2002
    Applicant: Ajinomoto Co., Inc.
    Inventors: Katsutoshi Sakata, Takashi Tsuji, Noriko Sasaki, Kazuyoshi Takahashi
  • Patent number: 6164405
    Abstract: A steering gear box mounting structure has a flexible support device for mounting a steering gear box to a vehicle body member and a flexible support device mounting portion for mounting the flexible support device to the steering gear box. The flexible support device is composed of an outer sleeve, an inner sleeve and an elastic body. The outer sleeve is conically shaped in its both axial end portions and is cylindrically shaped in its center portion. The inner sleeve is partially conically shaped in its axial end portions and is cylindrically shaped in its center portion. The elastic body is interposed between the outer and inner sleeves with a hollow space left therebetween. In the flexible support device, the outer sleeve is provided with an inclined surface inclined with respect to a direction perpendicular to the axis of the outer sleeve.
    Type: Grant
    Filed: November 12, 1998
    Date of Patent: December 26, 2000
    Assignee: Toyota Jidosha Kabushiki Kaisha
    Inventor: Katsutoshi Sakata
  • Patent number: 5900492
    Abstract: A method for resolving optically impure 3-oxa-2-oxobicyclo?3.1.0!hexane-1-carboxylic acid esters. A method is provided for producing a 1-alkoxycarbonyl-2-hydroxymethylcyclopropane-1-carboxylic acid.N-benzyl-.alpha.-phenylethylamine diastereomer salt. An enantiomer of N-benzyl-.alpha.-phenylethylamine is reacted with a 1-alkoxycarbonyl-2-hydroxymethylcyclopropane-1-carboxylic acid to produce a precipitate that is enriched in one diastereomer of the salt. After isolating the optically active salt, the N-benzyl-.alpha.-phenylethylamine may be separated to produce the corresponding 1-alkoxycarbonyl-2-hydroxymethylcyclopropane-1-carboxylic acid. Under acidic conditions, the carboxylic acid and hydroxyl groups undergo ring closure to afford the optically active 3-oxa-2-oxobicyclo?3.1.0!hexane-1-carboxylic acid ester.
    Type: Grant
    Filed: December 2, 1997
    Date of Patent: May 4, 1999
    Assignee: Ajinomoto Co., Inc.
    Inventors: Katsutoshi Sakata, Takashi Tsuji, Noriyasu Kataoka, Masanobu Yatagai