Patents by Inventor Kazuhiko Nakano
Kazuhiko Nakano has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 9604619Abstract: A brake control apparatus includes a master cylinder configured to generate a brake pressure according to a depressing force of a brake pedal; an electric motor configured to operate the master cylinder; a control board configured to control the electric motor; and a board receiving portion arranged along an outer circumference of the master cylinder. The board receiving portion receives the control board such that a component-mounting surface of the control board faces in an axial direction of the master cylinder.Type: GrantFiled: February 11, 2014Date of Patent: March 28, 2017Assignee: Hitachi Automotive Systems, Ltd.Inventors: Hirofumi Watanabe, Daisuke Yasukawa, Kazuhiko Nakano
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Publication number: 20160311858Abstract: An object of the present invention is to provide methods of discovering drugs effective for tough targets, which have conventionally been discovered only with difficulty. The present invention relates to novel methods for cyclizing peptide compounds, and novel peptide compounds and libraries comprising the same, to achieve the above object.Type: ApplicationFiled: May 27, 2016Publication date: October 27, 2016Applicant: Chugai Seiyaku Kabushiki KaishaInventors: Shiori Kariyuki, Takeo Iida, Miki Kojima, Ryuichi Takeyama, Mikimasa Tanada, Tetsuo Kojima, Hitoshi Iikura, Atsushi Matsuo, Takuya Shiraishi, Takashi Emura, Kazuhiko Nakano, Koji Takano, Kousuke Asou, Takuya Torizawa, Ryusuke Takano, Nozomi Hisada, Naoaki Murao, Atsushi Ohta, Kaori Kimura, Yusuke Yamagishi, Tatsuya Kato
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Publication number: 20160262257Abstract: To increase vibration resistance of a connection terminal, a tip of which is soldered to a circuit board. In a controller, the circuit board is accommodated in a controller housing made of metal, and the tip of the connection terminal that extends from an actuator housing through an opening is fixed to the circuit board. Semiconductor switching elements and electrolytic capacitors as heat generating components are collectively arranged in an area of the circuit board adjacent to the connection terminal, and the circuit board is adhered and fixed to a top surface of a heat mass via a thermal conductive adhesive. At the same time as that heat dissipation is improved by the thermal conductive adhesive, a load caused by vibration is reduced because the circuit board is fixed at a position near the connection terminal to the controller housing.Type: ApplicationFiled: March 4, 2016Publication date: September 8, 2016Inventors: Hirofumi WATANABE, Mototaka TAKAHASHI, Kazuhiko NAKANO
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Patent number: 9409952Abstract: An object of the present invention is to provide methods of discovering drugs effective for tough targets, which have conventionally been discovered only with difficulty. The present invention relates to novel methods for cyclizing peptide compounds, and novel peptide compounds and libraries comprising the same, to achieve the above object.Type: GrantFiled: December 28, 2012Date of Patent: August 9, 2016Assignee: Chugai Seiyaku Kabushiki KaishaInventors: Shiori Kariyuki, Takeo Iida, Miki Kojima, Ryuichi Takeyama, Mikimasa Tanada, Tetsuo Kojima, Hitoshi Iikura, Atsushi Matsuo, Takuya Shiraishi, Takashi Emura, Kazuhiko Nakano, Koji Takano, Kousuke Asou, Takuya Torizawa, Ryusuke Takano, Nozomi Hisada, Naoaki Murao, Atsushi Ohta, Kaori Kimura, Yusuke Yamagishi, Tatsuya Kato
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Patent number: 9297811Abstract: Disclosed is the construction of a system capable of quickly and easily identifying patients having a risk for worsening inflammatory digestive tract disease by identifying a causal factor for the worsening of the inflammatory digestive tract disease. Specifically disclosed is a method for detecting oral bacteria that cause worsening of inflammatory digestive tract disease and/or a screening that targets high risk for worsening of inflammatory digestive tract disease and/or determining the risk for worsening of the inflammatory digestive tract disease by PA not being detected and/or CBP being detected, inclusive of the detection of PA, which is an oral bacteria protein antigen, and/or CBP, which is collagen binding protein, in samples. Also disclosed are a detection reagent and kit used for this method.Type: GrantFiled: March 10, 2011Date of Patent: March 29, 2016Assignees: National University Corporation Hamamatsu University School of Medicine, Osaka UniversityInventors: Kazuo Umemura, Kazuya Hokamura, Kazuhiko Nakano, Takashi Ooshima, Ryota Nomura, Koichiro Wada
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Publication number: 20160082908Abstract: An electronic control apparatus includes an electric motor including a rotor and a stator; a circuit board configured to drivingly control the electric motor; and a housing unit accommodating the electric motor and the circuit board. A vehicle-body attaching portion of the housing unit is attached and fixed to a vehicle body. The vehicle-body attaching portion is located on one side of the rotor with respect to an extending direction of the rotor. At least one of both surfaces of the circuit board is a component-mounting surface. The circuit board is fixed to the housing unit in a state where the both surface of the circuit board extend along the rotor of the electric motor. A large-size electronic component is mounted on a vehicle-body-attaching-portion-side portion of a peripheral portion of the component-mounting surface which is close to the vehicle-body attaching portion.Type: ApplicationFiled: September 8, 2015Publication date: March 24, 2016Applicant: HITACHI AUTOMOTIVE SYSTEMS, LTD.Inventors: Kazuhiko NAKANO, Kiminori MUTO, Daisuke YASUKAWA, Hirofumi WATANABE
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Patent number: 9180852Abstract: An electric booster includes a housing having one end including a coupling surface where the housing is coupled to a master cylinder, and the other end including an attachment surface where the housing is attached to a vehicle. A controller includes a flat plate-like control board, and the control board is disposed so as to be positioned between a first plane including the attachment surface of the housing where the housing is attached to the vehicle, and a second plane including the coupling surface of the housing where the housing is coupled to the master cylinder.Type: GrantFiled: January 28, 2013Date of Patent: November 10, 2015Assignee: HITACHI AUTOMOTIVE SYSTEMS, LTD.Inventors: Daichi Nomura, Takuya Usui, Toshiyuki Ajima, Hidefumi Iwaki, Kazuhiko Nakano, Hirohumi Watanabe
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Patent number: 9060440Abstract: A supporting structure comprises a base member to support a printed circuit board, a holder standing upright from the base member and supporting the printed circuit board; and a support standing upright from the base member and supporting the printed circuit board sidewise. The support includes a column standing upright from the base member, and having a modulus of elasticity greater than that of the holder, and an abutment portion to abut on a side surface of the printed circuit board.Type: GrantFiled: March 28, 2013Date of Patent: June 16, 2015Assignee: HITACHI AUTOMOTIVE SYSTEMS, LTD.Inventors: Hirofumi Watanabe, Kazuhiko Nakano, Daisuke Yasukawa
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Publication number: 20150075156Abstract: Disclosed is a brake control apparatus including a master cylinder that generates a hydraulic braking pressure in response to operation of a brake pedal, an electric motor that drives the master cylinder, a housing in which the master cylinder and the electric motor are assembled, and a control unit adapted to perform drive control of the electric motor. The control unit has a bottom formed at least partially integral with the housing and includes a circuit board mounting thereon drive elements to drive the electric motor. The brake control apparatus includes a heat radiating seat located on an inner surface of the bottom of the control unit at a position apart from the electric motor and closer to the master cylinder than the electric motor and brought into thermal contact with the circuit board so as to radiate heat of the drive elements toward the housing.Type: ApplicationFiled: August 29, 2014Publication date: March 19, 2015Inventors: Kazuhiko NAKANO, Hirofumi WATANABE, Daisuke YASUKAWA
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Publication number: 20150080549Abstract: An object of the present invention is to provide methods of discovering drugs effective for tough targets, which have conventionally been discovered only with difficulty. The present invention relates to novel methods for cyclizing peptide compounds, and novel peptide compounds and libraries comprising the same, to achieve the above object.Type: ApplicationFiled: December 28, 2012Publication date: March 19, 2015Inventors: Shiori Kariyuki, Takeo Iida, Miki Kojima, Ryuichi Takeyama, Mikimasa Tanada, Tetsuo Kojima, Hitoshi Iikura, Atsushi Matsuo, Takuya Shiraishi, Takashi Emura, Kazuhiko Nakano, Koji Takano, Kousuke Asou, Takuya Torizawa, Ryusuke Takano, Nozomi Hisada, Naoaki Murao, Atsushi Ohta, Kaori Kimura, Yusuke Yamagishi, Tatsuya Kato
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Patent number: 8929079Abstract: An electronic control device comprises a circuit board having a heat generating part mounted thereon; a case for installing therein the circuit board, the case having a heat receiving portion that is in contact with the heat generating part; at least two first fixing units that are constructed and arranged to fix a peripheral portion of the circuit board to the case; and at least one second fixing unit that is arranged to fix a given area of the circuit board to the case while pressing the given area against the heat receiving portion through the heat generating part, the given area being an area where the heat generating part is placed.Type: GrantFiled: September 7, 2012Date of Patent: January 6, 2015Assignee: Hitachi Automotive Systems, Ltd.Inventors: Hirofumi Watanabe, Kazuhiko Nakano, Daisuke Yasukawa
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Publication number: 20140335121Abstract: The present invention has as its object to provide a process for determining the degree of pathogenicity of infecting bacterial strains in the case of canine periodontal disease. The present inventors found that Porphyromonas gulae is a major pathogen of canine periodontal disease, and demonstrated that the fimA genes encoding FimA (fimbrillin) protein which constitute fimbriae of this bacterium are classified into three major groups, and that each of the groups is correlated with the pathogenicity of this bacterium as a pathogenic bacterial of periodontal disease. Thus the inventors completed the present invention.Type: ApplicationFiled: December 13, 2012Publication date: November 13, 2014Inventors: Fumitoshi Asai, Yukio Kato, Mitsuyuki Shirai, Masaru Murakami, Kazuhiko Nakano, Ryota Nomura
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Publication number: 20140283513Abstract: A brake control apparatus includes a master cylinder configured to generate a brake pressure according to a depressing force of a brake pedal; an electric motor configured to operate the master cylinder; a control board configured to control the electric motor; and a board receiving portion arranged along an outer circumference of the master cylinder. The board receiving portion receives the control board such that a component-mounting surface of the control board faces in an axial direction of the master cylinder.Type: ApplicationFiled: February 11, 2014Publication date: September 25, 2014Applicant: Hitachi Automotive Systems, Ltd.Inventors: Hirofumi WATANABE, Daisuke YASUKAWA, Kazuhiko NAKANO
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Patent number: 8785777Abstract: An actuator control device includes a circuit device that is resin-molded by a plurality of metal molds including at least one movable metal mold to include a first bus bar and a second bus bar. The first bus bar and the second bus bar each include a flat plate-like portion that includes two main flat-face portions having large surface areas, and two sub flat-face portions that are adjacent to the main flat-face portions and have smaller surface areas than the surface areas of the main flat-face portions. One of the main flat-face portions of the first bus bar faces one of the main flat-face portions of the second bus bar. The facing direction differs from the mold release direction of the movable metal mold.Type: GrantFiled: December 22, 2010Date of Patent: July 22, 2014Assignee: Hitachi Automotive Systems, Ltd.Inventors: Daisuke Yasukawa, Hirofumi Watanabe, Kazuhiko Nakano, Kenji Kikuchi
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Patent number: 8729403Abstract: First and second terminals project from a circuit board and lie adjacent to each other with an interspace formed between the first and second terminals. An electronic apparatus further includes a projecting member projecting along a neighboring terminal which is one of the first and second terminals at such a position that the neighboring terminal is located between the projecting member and the interspace. The projecting member is located at an adjacent position adjacent to the neighboring terminal, to attract molten solder from the interspace toward the projecting member during soldering to join the first and second terminals to the circuit board.Type: GrantFiled: September 14, 2011Date of Patent: May 20, 2014Assignee: Hitachi Automotive Systems, Ltd.Inventors: Daisuke Yasukawa, Kazuhiko Nakano, Hirofumi Watanabe, Atsushi Yamaguchi
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Patent number: 8687374Abstract: An electronic controller for a vehicle includes a box-shaped frame having only one opened side that has a notch portion into which an electric connector whose connection port protrudes toward an outside fits and a cover that closes an opening of the frame, in which while a groove filled with a sealant is provided at least on a bonded surface of an electric connector to which the cover is bonded, a first convex portion that fits into the groove is provided in a circumferential portion of the cover. Moreover, the electric connector has a flange portion opposite to an inner wall of the frame around the notch portion, and the flange portion is provided with a second convex portion protruding toward the inner wall to surround the notch portion.Type: GrantFiled: March 21, 2011Date of Patent: April 1, 2014Assignee: Hitachi Automotive Systems, Ltd.Inventors: Hirofumi Watanabe, Kazuhiko Nakano, Daisuke Yasukawa
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Publication number: 20140085839Abstract: An electronic control device has an enclosure accommodating therein a circuit board and having (a) a first enclosure member which is provided at a connecting part thereof with a seal groove and (b) a second enclosure member which is provided at a connecting part thereof with a convex line that is fitted into the seal groove of the first enclosure member; a protrusion formed on either one of an inner wall surface in the seal groove or an opposing surface, which faces the inner wall surface of the seal groove, of the convex line so as to protrude toward the other surface. The protrusion limits a movement, in a seal groove width direction, of the convex line fitted into the seal groove. The seal groove and the convex line are sealed with a sealant.Type: ApplicationFiled: September 10, 2013Publication date: March 27, 2014Applicant: Hitachi Automotive Systems, Ltd.Inventors: Kazuhiko NAKANO, Hirofumi WATANABE, Daisuke YASUKAWA, Toshio OTSUBO
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Patent number: 8670234Abstract: An electronic control device for controlling an electric actuator, including an air passage within a casing that is fixable to an actuator housing of the electric actuator. A circuit board is accommodated in the casing. A projecting portion is formed in the casing, on which a region of the circuit board in which the heat generating part is installed is seated. A vent hole extends through the casing to communicate to an outside of the casing. A communication hole extends through the casing to communicate to an inside of the actuator housing. The air passage allows air to flow between the vent hole and the communication hole when the electric actuator is driven in a state that the casing is fixed to the actuator housing.Type: GrantFiled: May 14, 2012Date of Patent: March 11, 2014Assignee: Hitachi Automotive Systems, Ltd.Inventors: Kazuhiko Nakano, Hirofumi Watanabe, Daisuke Yasukawa
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Publication number: 20130286606Abstract: A supporting structure comprises a base member to support a printed circuit board, a holder standing upright from the base member and supporting the printed circuit board; and a support standing upright from the base member and supporting the printed circuit board sidewise. The support includes a column standing upright from the base member, and having a modulus of elasticity greater than that of the holder, and an abutment portion to abut on a side surface of the printed circuit board.Type: ApplicationFiled: March 28, 2013Publication date: October 31, 2013Applicant: HITACHI AUTOMOTIVE SYSTEMS, LTD.Inventors: Hirofumi WATANABE, Kazuhiko Nakano, Daisuke Yasukawa
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Publication number: 20130058044Abstract: An electronic control device comprises a circuit board having a heat generating part mounted thereon; a case for installing therein the circuit board, the case having a heat receiving portion that is in contact with the heat generating part; at least two first fixing units that are constructed and arranged to fix a peripheral portion of the circuit board to the case; and at least one second fixing unit that is arranged to fix a given area of the circuit board to the case while pressing the given area against the heat receiving portion through the heat generating part, the given area being an area where the heat generating part is placed.Type: ApplicationFiled: September 7, 2012Publication date: March 7, 2013Inventors: Hirofumi Watanabe, Kazuhiko Nakano, Daisuke Yasukawa