Abstract: In a topical adhesive skin patch provided with a support and a base material layer laminated to one or both sides of the support, or in a topical adhesive skin patch intended to be used by placing only a gel sheet against the skin surface, the base material layer or gel sheet includes an oil-in-water type gel base containing at least water, oil, an emulsifier, and a water-absorbent polymer, such that prior to application to the skin surface, the base material layer or gel sheet is opaque due to emulsification of the base material layer or gel sheet, and subsequent to application to the skin surface, moisture contained in the base material layer or gel sheet gradually evaporates causing the opacity of the base material layer or gel sheet to decline over time, so that decline in opacity over time can be visually ascertained.

Abstract: An object of the present invention is to provide a composition for external application that is applied to a part of the skin to more effectively elicit the useful effects of an adenine compound such as adenine, adenosine, and a phosphoric ester of adenosine, and that has long-lasting effects and enhanced skin-moisturizing effects. A gel composition for external application containing an adenine compound such as adenine, adenosine, and a phosphoric ester of adenosine is prepared by using agar as a gelling agent. The gel composition is further prepared in the form of a sheet-like adhesive patch. The gel composition in the form of a sheet-like adhesive patch is kept immersed in an aqueous solution containing the adenine compound.

Abstract: In a topical adhesive skin patch provided with a support and a base material layer laminated to one or both sides of the support, or in a topical adhesive skin patch intended to be used by placing only a gel sheet against the skin surface, the base material layer or gel sheet includes an oil-in-water type gel base containing at least water, oil, an emulsifier, and a water-absorbent polymer, such that prior to application to the skin surface, the base material layer or gel sheet is opaque due to emulsification of the base material layer or gel sheet, and subsequent to application to the skin surface, moisture contained in the base material layer or gel sheet gradually evaporates causing the opacity of the base material layer or gel sheet to decline over time, so that decline in opacity over time can be visually ascertained.

Abstract: An external preparation kit is provided, which has a gel sheet having excellent water-releasing property and elongation, and a water-soluble sheet having excellent solubility. Thus, an external preparation kit according to the invention comprises: (I) a gel sheet containing: (a) 1-6% by mass of a composition comprising 10-80% by mass of carrageenan, 5-50% by mass of locust bean gum, 5-50% by mass of xanthan gum, and 5-50% by mass of mannan; and (b) water; and (II) a water-soluble sheet containing one or more component(s) selected from the group consisting of a cellulose derivative, polyvinyl alcohol, collagen, starch, gelatin, agar, and sugar.

Abstract: An external preparation kit is provided, which has a gel sheet having excellent water-releasing property and elongation, and a water-soluble sheet having excellent solubility. Thus, an external preparation kit according to the invention comprises: (I) a gel sheet containing: (a) 1-6% by mass of a composition comprising 10-80% by mass of carrageenan, 5-50% by mass of locust bean gum, 5-50% by mass of xanthan gum, and 5-50% by mass of mannan; and (b) water; and (II) a water-soluble sheet containing one or more component(s) selected from the group consisting of a cellulose derivative, polyvinyl alcohol, collagen, starch, gelatin, agar, and sugar.

Abstract: An object of the present invention is to provide a composition for external application that is applied to a part of the skin to more effectively elicit the useful effects of an adenine compound such as adenine, adenosine, and a phosphoric ester of adenosine, and that has long-lasting effects and enhanced skin-moisturizing effects. A gel composition for external application containing an adenine compound such as adenine, adenosine, and a phosphoric ester of adenosine is prepared by using agar as a gelling agent. The gel composition is further prepared in the form of a sheet-like adhesive patch. The gel composition in the form of a sheet-like adhesive patch is kept immersed in an aqueous solution containing the adenine compound.