Patents by Inventor Kazuki Onoue

Kazuki Onoue has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Fluorescent probe for imaging lymph nodes
    Patent number: 9957392
    Abstract: Disclosed is a near-infrared fluorescent imaging agent comprising an indocyanine-based fluorescent dye and a liposome. The near-infrared fluorescent imaging agent of the present invention demonstrates high fluorescence intensity and a long anchoring time in sentinel lymph nodes, thereby making it useful for detecting sentinel lymph nodes in sentinel lymph node navigation surgery. Also disclosed is an indocyanine green derivative that is particularly suitable for use in the near-infrared fluorescent imaging agent of the present invention.
    Type: Grant
    Filed: January 29, 2016
    Date of Patent: May 1, 2018
    Assignee: Eisai R&D Management Co., Ltd.
    Inventors: Hideki Hayashi, Masanori Fujinami, Taro Toyota, Yutaka Tamura, Akira Aoki, Yutaka Muraki, Kazuki Onoue
  • Fluorescent Probe for Imaging Lymph Nodes
    Publication number: 20160222211
    Abstract: Disclosed is a near-infrared fluorescent imaging agent comprising an indocyanine-based fluorescent dye and a liposome. The near-infrared fluorescent imaging agent of the present invention demonstrates high fluorescence intensity and a long anchoring time in sentinel lymph nodes, thereby making it useful for detecting sentinel lymph nodes in sentinel lymph node navigation surgery. Also disclosed is an indocyanine green derivative that is particularly suitable for use in the near-infrared fluorescent imaging agent of the present invention.
    Type: Application
    Filed: January 29, 2016
    Publication date: August 4, 2016
    Inventors: Hideki Hayashi, Masanori Fujinami, Taro Toyota, Yutaka Tamura, Akira Aoki, Yutaka Muraki, Kazuki Onoue
  • Fluorescent probe for imaging lymph nodes
    Patent number: 9302018
    Abstract: Disclosed is a near-infrared fluorescent imaging agent comprising an indocyanine-based fluorescent dye and a liposome. The near-infrared fluorescent imaging agent of the present invention demonstrates high fluorescence intensity and a long anchoring time in sentinel lymph nodes, thereby making it useful for detecting sentinel lymph nodes in sentinel lymph node navigation surgery. Also disclosed is an indocyanine green derivative that is particularly suitable for use in the near-infrared fluorescent imaging agent of the present invention.
    Type: Grant
    Filed: May 31, 2011
    Date of Patent: April 5, 2016
    Assignee: Eisai R&D Management Co., Ltd.
    Inventors: Hideki Hayashi, Masanori Fujinami, Taro Toyota, Yutaka Tamura, Akira Aoki, Yutaka Muraki, Kazuki Onoue
  • Fluorescent Probe for Imaging Lymph Nodes
    Publication number: 20130129631
    Abstract: Disclosed is a near-infrared fluorescent imaging agent comprising an indocyanine-based fluorescent dye and a liposome. The near-infrared fluorescent imaging agent of the present invention demonstrates high fluorescence intensity and a long anchoring time in sentinel lymph nodes, thereby making it useful for detecting sentinel lymph nodes in sentinel lymph node navigation surgery. Also disclosed is an indocyanine green derivative that is particularly suitable for use in the near-infrared fluorescent imaging agent of the present invention.
    Type: Application
    Filed: May 31, 2011
    Publication date: May 23, 2013
    Applicant: NATIONAL UNIVERSITY CORPORATION CHIBA UNIVERSITY
    Inventors: Hideki Hayashi, Masanori Fujinami, Taro Toyota, Yutaka Tamura, Akira Aoki, Yutaka Muraki, Kazuki Onoue