Patents by Inventor Kazuki Shimizu
Kazuki Shimizu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20180257718Abstract: A vehicle upper section structure includes a roof side-rail, a roof panel, and a side outer panel. The roof side-rail is provided at a vehicle width direction end of a vehicle upper section. The roof panel is formed from a material having a higher linear expansion coefficient than that of a material of the roof side-rail, and is provided at a vehicle width direction central portion of the vehicle upper section. The side outer panel is formed from a material having a higher linear expansion coefficient than that of the material of the roof side-rail, is provided at an outer side of a vehicle further than the roof side-rail, and includes a first join joined to the roof side-rail and a second join joined to the roof panel. The first join and the second join are separated from each other.Type: ApplicationFiled: January 10, 2018Publication date: September 13, 2018Applicant: TOYOTA JIDOSHA KABUSHIKI KAISHAInventors: Ayaka KAGAMI, Kazuki SHIMIZU
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Patent number: 10059377Abstract: Provided is a vehicle frame structure including (1) a first frame member that has a closed cross-sectional shape as seen in a cross-sectional view orthogonal to an extension direction and (2) a second frame member that extends along the first frame member, overlaps a wall surface of the first frame member, and has a hole portion that exposes the wall surface, with an edge portion of the hole portion being joined to the wall surface by a linear welded portion, wherein both end portions of the welded portion are disposed in close proximity to a neutral axis of the first frame member and the second frame member in a case in which the first frame member and the second frame member have undergone bending deformation in an in-plane direction of the wall surface in which the welded portion is formed.Type: GrantFiled: July 13, 2017Date of Patent: August 28, 2018Assignee: TOYOTA JIDOSHA KABUSHIKI KAISHAInventor: Kazuki Shimizu
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Patent number: 10053151Abstract: A reinforcing structure of a vehicle frame member includes: ribs that integrally connect standing wall portions, that are formed at a planar portion of a vehicle frame member, to one another, and that reinforce the planar portion; portions of gradually changing thickness that are formed at connected portions of the ribs with the standing wall portions; portions of gradually changing height that are formed at the connected portions of the ribs with the standing wall portions; first curved portions that are formed at the portions of gradually changing thickness; second curved portions that are formed at the portions of gradually changing thickness; third curved portions that are formed at the portions of gradually changing height; and fourth curved portions that are formed at the portions of gradually changing height.Type: GrantFiled: December 7, 2016Date of Patent: August 21, 2018Assignee: TOYOTA JIDOSHA KABUSHIKI KAISHAInventors: Soshiro Murata, Takashi Sasaki, Hideaki Kanasugi, Kazuki Shimizu, Minako Izumi
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Publication number: 20180105213Abstract: A suspension member includes: a pair of left and right front body mounts, each of which has a front side rail part extending in a front-rear direction of a vehicle body, and a cross part extending inward in a vehicle width direction; a front cross member extending in the vehicle width direction, in which both end parts of the front cross member in the vehicle width direction are joined to the cross parts, respectively; and a protective member that extends in the vehicle width direction and covers an entire lower wall of the front cross member, has a jack-up part for a jack to be applied, and is joined to the lower wall of the front cross member, the jack-up part being provided integrally in the protective member.Type: ApplicationFiled: October 11, 2017Publication date: April 19, 2018Applicant: TOYOTA JIDOSHA KABUSHIKI KAISHAInventors: Ayaka KAGAMI, Hideaki Kanasugi, Kazuki Shimizu
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Publication number: 20180037266Abstract: Provided is a vehicle frame structure including (1) a first frame member that has a closed cross-sectional shape as seen in a cross-sectional view orthogonal to an extension direction and (2) a second frame member that extends along the first frame member, overlaps a wall surface of the first frame member, and has a hole portion that exposes the wall surface, with an edge portion of the bole portion being joined to the wall surface by a linear welded portion, wherein both end portions of the welded portion are disposed in close proximity to a neutral axis of the first frame member and the second frame member in a case in which the first frame member and the second frame member have undergone bending deformation in an in-plane direction of the wall surface in which the welded portion is formed.Type: ApplicationFiled: July 13, 2017Publication date: February 8, 2018Applicant: TOYOTA JIDOSHA KABUSHIKI KAISHAInventor: Kazuki SHIMIZU
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Publication number: 20180009480Abstract: A suspension member includes: a front frame including a front cross member extending in a vehicle width direction; a rear frame at least partially made of light metal and including a rear cross member extending in the vehicle width direction, the rear frame being placed on a vehicle rear side of the front frame and joined to the front frame; and a protective member joined to the rear cross member so as to form a closed section together with the rear cross member.Type: ApplicationFiled: June 27, 2017Publication date: January 11, 2018Applicant: TOYOTA JIDOSHA KABUSHIKI KAISHAInventors: Ayaka KAGAMI, Kazuki SHIMIZU
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Publication number: 20170183036Abstract: A reinforcing structure of a vehicle frame member includes: ribs that integrally connect standing wall portions, that are formed at a planar portion of a vehicle frame member, to one another, and that reinforce the planar portion; portions of gradually changing thickness that are formed at connected portions of the ribs with the standing wall portions; portions of gradually changing height that are formed at the connected portions of the ribs with the standing wall portions; first curved portions that are formed at the portions of gradually changing thickness; second curved portions that are formed at the portions of gradually changing thickness; third curved portions that are formed at the portions of gradually changing height; and fourth curved portions that are formed at the portions of gradually changing height.Type: ApplicationFiled: December 7, 2016Publication date: June 29, 2017Applicant: TOYOTA JIDOSHA KABUSHIKI KAISHAInventors: Soshiro MURATA, Takashi SASAKI, Hideaki KANASUGI, Kazuki SHIMIZU, Minako IZUMI
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Patent number: 8927236Abstract: It is an objective of the present invention to provide a process for efficiently producing poly-?-glutamic acid having a high L-glutamic acid content and excellent quality. The process for producing poly-?-glutamic acid according to the present invention is characterized in using a bacterium belonging to species Bacillus megaterium.Type: GrantFiled: January 31, 2007Date of Patent: January 6, 2015Assignee: Kochi UniversityInventors: Makoto Ashiuchi, Kazuki Shimizu
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Patent number: 7985744Abstract: The object of the present invention is to provide vitamin D derivatives that have excellent physiological activities as medicines, particularly as therapeutic agents for skin diseases such as psoriasis, and that have a reduced hypercalcemic effect. The present invention provides a vitamin D derivative of Formula (1): wherein X represents an oxygen atom or a sulfur atom; m represents a number of 1 to 3; R1 and R2 each represent a hydrogen atom or an alkyl group; R4 and R5 each represent a hydrogen atom or a hydroxyl group, etc.; R3 represents —YR8, etc.; R6 represents a hydrogen atom, etc.; R7 represents a hydrogen atom, etc.Type: GrantFiled: June 14, 2001Date of Patent: July 26, 2011Assignee: Chugai Seiyaku Kabushiki KaishaInventors: Kazumi Morikawa, Masayuki Ohmori, Kazuki Shimizu, Akira Kawase, Takashi Emura
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Patent number: 7935688Abstract: The present invention provides a compound represented by the following general formula (I): or a pharmaceutically acceptable salt thereof, a pharmaceutical composition containing such a compound, and the like. The compound or a pharmaceutically acceptable salt thereof, the pharmaceutical composition containing such a compound, or the like is useful as a medicine or the like for therapy of benign prostatic hyperplasia, cancer, osteoporosis, psoriasis, secondary hyperparathyroidism, chronic glomerulonephritis, lupus nephritis and/or diabetic nephropathy and the like.Type: GrantFiled: June 9, 2006Date of Patent: May 3, 2011Assignee: Chugai Seiyaku Kabushiki KaishaInventors: Tadakatsu Takahashi, Yoshiyuki Ono, Hirotaka Kashiwagi, Tsuyoshi Haneishi, Kazuki Shimizu
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Publication number: 20110060146Abstract: The present invention provides a compound represented by the following general formula (I): or a pharmaceutically acceptable salt thereof, a pharmaceutical composition containing such a compound, and the like. The compound or a pharmaceutically acceptable salt thereof, the pharmaceutical composition containing such a compound, or the like is useful as a medicine or the like for therapy of benign prostatic hyperplasia, cancer, osteoporosis, psoriasis, secondary hyperparathyroidism, chronic glomerulonephritis, lupus nephritis and/or diabetic nephropathy and the like.Type: ApplicationFiled: November 15, 2010Publication date: March 10, 2011Applicant: CHUGAI SEIYAKU KABUSHIKI KAISHAInventors: TADAKATSU TAKAHASHI, YOSHIYUKI ONO, HIROTAKA KASHIWAGI, TSUYOSHI HANEISHI, KAZUKI SHIMIZU
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Publication number: 20100233764Abstract: It is an objective of the present invention to provide a process for efficiently producing poly-?-glutamic acid having a high L-glutamic acid content and excellent quality. The process for producing poly-?-glutamic acid according to the present invention is characterized in using a bacterium belonging to species Bacillus megaterium.Type: ApplicationFiled: January 31, 2007Publication date: September 16, 2010Applicant: Kochi UniversityInventors: Makoto Ashiuchi, Kazuki Shimizu
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Publication number: 20090137609Abstract: The present invention provides a compound represented by the following general formula (I): or a pharmaceutically acceptable salt thereof, a pharmaceutical composition containing such a compound, and the like. The compound or a pharmaceutically acceptable salt thereof, the pharmaceutical composition containing such a compound, or the like is useful as a medicine or the like for therapy of benign prostatic hyperplasia, cancer, osteoporosis, psoriasis, secondary hyperparathyroidism, chronic glomerulonephritis, lupus nephritis and/or diabetic nephropathy and the like.Type: ApplicationFiled: June 9, 2006Publication date: May 28, 2009Applicant: Chugai Seiyaku Kabushiki KaishaInventors: Tadakatsu Takahashi, Yoshiyuki Ono, Hirotaka Kashiwagi, Tsuyoshi Haneishi, Kazuki Shimizu
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Publication number: 20080271802Abstract: A lining material composed of felt impregnated with a thermosetting resin is used to line a pipe to be rehabilitated. 0.5 to 30 wt % of a filler containing at least carbon nanotubes is added to the thermosetting resin impregnated in the felt of the lining material in order to improve the thermal conductivity of the felt. The thermal conductivity is greatly improved up to 0.3 W/m·K or greater over the conventional thermal conductivity of 0.2 W/m·K, making it possible to reduce the time needed for heating, and to heat the lining material more uniformly.Type: ApplicationFiled: March 27, 2008Publication date: November 6, 2008Inventors: Takao Kamiyama, Kazuki Shimizu, Kunio Nishimura
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Publication number: 20080272110Abstract: An electric heating apparatus comprises a sheet heating element having two end electrodes and a center electrode. The sheet heating element is wound around the external peripheral surface of an airtight and elastic expandable balloon. The balloon is disposed inside a lining material impregnated with a thermosetting resin for repairing a pipe and is swelled against the inside wall of the pipe through the lining material. The end and center electrodes are supplied with electricity to generate heat in the sheet heating element, thereby curing the thermosetting resin impregnated in the lining material. This allows pipe lining to be performed with much higher energy efficiency and simpler steps.Type: ApplicationFiled: March 27, 2008Publication date: November 6, 2008Inventors: Takao Kamiyama, Guochun Xu, Kazuki Shimizu, Takashi Ookubo, Youshitaka Arii
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Publication number: 20080241779Abstract: A continuous-atmosphere high-temperature furnace apparatus comprises a high-temperature furnace section, a mechanism for continuously supplying substrates or samples to the high-temperature furnace section, and a mechanism for continuously discharging treated substrates or samples from the high-temperature furnace section. Gas is exhausted from the high-temperature furnace section and ambient gas is supplied thereto for reaction to produce carbon materials and various other nanomaterials or to burn and graphitize the nanomaterials. The substrates or samples are sequentially moved for heat treatment, thereby improving the work efficiency of the high-temperature furnace.Type: ApplicationFiled: March 27, 2008Publication date: October 2, 2008Inventors: Takao Kamiyama, Guochun Xu, Kazuki Shimizu
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Patent number: 7074777Abstract: The object of the present invention is to provide a vitamin D derivative exhibiting excellent physiological activity as medicines, in particular as therapeutic agents for skin disease including psoriasis, and having decreased hypercalcemic activity. The present invention provides vitamin D derivatives represented by the general Formula (1): wherein in Formula (1), X is oxygen or sulfur; R1 is hydrogen or Formula (2) R2 is hydrogen or alkyl; R3 and R4 are hydrogen or alkyl or R3 and R4 together form a double bond between the 16- and 17-positions; R5 is hydrogen or —OR13 in which R13 is hydrogen or a protecting group; and R6 is hydrogen or a protecting group.Type: GrantFiled: April 18, 2001Date of Patent: July 11, 2006Assignee: Chugai Seiyaku Kabushiki KaishaInventors: Akira Kawase, Hitoshi Shimizu, Kazuki Shimizu, Takashi Emura, Kazutomo Kinoshita
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Publication number: 20060025474Abstract: The present invention discloses bisphenyl compounds of the formula: wherein R1, R2, R3, R4, R5, R6, X, Y, W are defined herein after. These compounds are useful as pharmaceuticals.Type: ApplicationFiled: March 8, 2005Publication date: February 2, 2006Inventors: David Wallace, Thomas Arrhenius, Anna Russell, Dingguo Liu, Amy Xing, Sovouthy Tith, Zheng Hou, Tadakatsu Takahashi, Yoshiyuki Ono, Hirotaka Kashiwagi, Kazuki Shimizu, Hitoshi Ikura
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Publication number: 20040019023Abstract: The object of the present invention is to provide vitamin D derivatives that have excellent physiological activities as medicines, particularly as therapeutic agents for skin diseases such as psoriasis, and that have a reduced hypercalcemic effect.Type: ApplicationFiled: July 21, 2003Publication date: January 29, 2004Inventors: Kazumi Morikawa, Masayuki Ohmori, Kazuki Shimizu, Akira Kawase, Takashi Emura
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Publication number: 20030195176Abstract: The object of the present invention is to provide a vitamin D derivative exhibiting excellent physiological activity as medicines, in particular as therapeutic agents for skin disease including psoriasis, and having decreased hypercalcemic activity.Type: ApplicationFiled: October 17, 2002Publication date: October 16, 2003Inventors: Akira Kawase, Hitoshi Shimizu, Kazuki Shimizu, Takashi Emura, Kazutomo Kinoshita