Abstract: A nebulizer capable of reliably intermittently applying a biological tissue adhesive is provided. A biological tissue adhesive nebulizer includes a first tube 30 for injecting a first solution containing a first component, and a second tube 30 for injecting a second solution containing a second component that promotes clot formation of the first component. The first solution injected from the first tube and the second solution injected from the second tube are mixed to generate and spray a biological tissue adhesive. A partition wall 34 is provided between a distal end 31 of the first tube and a distal end 31 of the second tube.

Abstract: A nebulizer capable of reliably intermittently applying a biological tissue adhesive is provided. A biological tissue adhesive nebulizer includes a first tube 30 for injecting a first solution containing a first component, and a second tube 30 for injecting a second solution containing a second component that promotes clot formation of the first component. The first solution injected from the first tube and the second solution injected from the second tube are mixed to generate and spray a biological tissue adhesive. A partition wall 34 is provided between a distal end 31 of the first tube and a distal end 31 of the second tube.

Abstract: The present disclosure relates to methods useful for determining whether to treat cancer in a patient, and treating cancer in a patient, by administering a therapeutically effective amount of Compound 1 and/or tautomers thereof or a pharmaceutically acceptable salt or hydrate thereof.

Abstract: A control parameter optimizing system and an operation optimizing apparatus equipped therewith are provided, the system being applicable to an existing plant without modifying the control panel or equipment of the plant, the system further being capable of optimizing the operation control of the plant in accordance with diverse operational requirements. The system includes an objective function setting section, a plant model, and a control parameter optimizing section. The control parameter optimizing section includes an optimization control parameter selecting section and an optimization control parameter adjusting section. The optimization control parameter selecting section selects as an optimization control parameter the control parameter for optimizing an objective function based on control logic information extracted from a power plant.

Abstract: Provided is a control parameter automatic-adjustment apparatus that adjusts a control parameter which is used when a control apparatus of a plant calculates an operational control signal, the apparatus including: a simulator that simulates operation of the plant; a learning unit that searches for an optimal control parameter using the simulator; and a knowledge database that stores knowledge information which associates an amount of change in the control parameter with an amount of change in a state of the plant, in which the learning unit includes a search range determination unit that determines a control parameter search range based on the knowledge information that is stored in the knowledge database.

Abstract: A control parameter optimizing system and an operation optimizing apparatus equipped therewith are provided, the system being applicable to an existing plant without modifying the control panel or equipment of the plant, the system further being capable of optimizing the operation control of the plant in accordance with diverse operational requirements. The system includes an objective function setting section, a plant model, and a control parameter optimizing section. The control parameter optimizing section includes an optimization control parameter selecting section and an optimization control parameter adjusting section. The optimization control parameter selecting section selects as an optimization control parameter the control parameter for optimizing an objective function based on control logic information extracted from a power plant.

Abstract: A control parameter optimizing system and an operation optimizing apparatus equipped therewith are provided, the system being applicable to an existing plant without modifying the control panel or equipment of the plant, the system further being capable of optimizing the operation control of the plant in accordance with diverse operational requirements. The system includes an objective function setting section, a plant model, and a control parameter optimizing section. The control parameter optimizing section includes an optimization control parameter selecting section and an optimization control parameter adjusting section. The optimization control parameter selecting section selects as an optimization control parameter the control parameter for optimizing an objective function based on control logic information extracted from a power plant.

Abstract: To provide a start-up control device and a start-up control method for a power plant capable of changing the start-up completion estimated time to a desired time simply and safely while starting the power plant.

Abstract: There is provided a combined cycle power plant in which a high-pressure steam turbine and an intermediate-pressure steam turbine can operate in a state where amounts of thermal effect thereof are close to a limit value, and capable of reducing start-up time. A combined cycle power plant includes: an exhaust heat recovery boiler that includes a high-pressure superheater which superheats steam for a high-pressure steam turbine, and a reheater which reheats steam for an intermediate-pressure steam turbine; bypass pipes through which steam bypasses the high-pressure superheater and the reheater; bypass valves that regulate flow rates of steam which flows through the bypass pipes; and a bypass controller that controls the bypass valves such that a difference between thermal effect-amount margins of the turbines is decreased.

Abstract: An activation control apparatus permits activating a steam turbine safely at high speed in response to a power generation plant state. A heat source apparatus heats low-temperature fluid to generate high-temperature fluid, and steam generation equipment generates steam by thermal exchange with the high-temperature fluid. A steam turbine is driven by the steam, and an adjustment apparatus adjusts a plant operation amount. A thermal effect amount prediction calculation device calculates a prediction value for a thermal effect amount for use for activation control of the steam turbine, and a changeover device decides, based on a state value of the power generation plant, the sensitivity of the thermal effect amount to a variation of the plant operation amount and outputs a changeover signal in accordance with the sensitivity. Based on the changeover signal, an adjustment device calculates the plant operation amount so as not to exceed a predetermined limit value.

Abstract: A steam turbine power plant includes a life consumption amount calculator configured to calculate life consumption amounts of a turbine rotor based on a value measured by a measurer, a thermal stress limit update timing determining device configured to determine a time when thermal stress limits are updated, an accumulated life consumption amount calculator configured to calculate accumulated life consumption amounts of the turbine rotor when the thermal stress limits are updated, a planned life consumption amount setting device configured to set planned life consumption amounts of the turbine rotor based on the accumulated life consumption amounts of the turbine rotor, a thermal stress limit calculator configured to calculate and update the thermal stress limits based on the planned life consumption amounts of the turbine rotor, and a plant command value calculator configured to calculate a plant command value based on the thermal stress limits.

Abstract: Provided is a steam turbine plant activation control device that can flexibly handle an initial state amount of a steam turbine plant and activate a steam turbine at a high speed. The activation control device 21 for the steam turbine plant includes a heat source device 1 configured to heat a low-temperature fluid using a heat source medium and generate a high-temperature fluid, a steam generator 2 for generating steam by thermal exchange with the high-temperature fluid, a steam turbine 3 to be driven by the steam, and adjusters 11, 12, 13, 14, 15 configured to adjust operation amounts of the plant.

Abstract: A steam turbine plant of the present invention includes a heat source device that heats a low temperature fluid by a heat source medium to obtain a high temperature fluid, a steam generating device that generates steam by heat exchange with the high temperature fluid, a steam turbine that is driven by the steam, a heating flow path that is disposed on an outer surface of a casing of the steam turbine, a high temperature fluid supply passage that is branched from a flow path of the high temperature fluid in the steam generating device, is connected to the heating flow path, and supplies the high temperature fluid to the heating flow path, and a high temperature fluid flow rate regulating device that regulates a flow rate of the high temperature fluid flowing through the high temperature fluid supply passage.

Abstract: Provided is a control parameter automatic-adjustment apparatus that adjusts a control parameter which is used when a control apparatus of a plant calculates an operational control signal, the apparatus including: a simulator that simulates operation of the plant; a learning unit that searches for an optimal control parameter using the simulator; and a knowledge database that stores knowledge information which associates an amount of change in the control parameter with an amount of change in a state of the plant, in which the learning unit includes a search range determination unit that determines a control parameter search range based on the knowledge information that is stored in the knowledge database.

Abstract: To provide a start-up control device and a start-up control method for a power plant capable of changing the start-up completion estimated time to a desired time simply and safely while starting the power plant.

Abstract: There is provided a combined cycle power plant in which a high-pressure steam turbine and an intermediate-pressure steam turbine can operate in a state where amounts of thermal effect thereof are close to a limit value, and capable of reducing start-up time. A combined cycle power plant includes: an exhaust heat recovery boiler that includes a high-pressure superheater which superheats steam for a high-pressure steam turbine, and a reheater which reheats steam for an intermediate-pressure steam turbine; bypass pipes through which steam bypasses the high-pressure superheater and the reheater; bypass valves that regulate flow rates of steam which flows through the bypass pipes; and a bypass controller that controls the bypass valves such that a difference between thermal effect-amount margins of the turbines is decreased.

Abstract: A p-type semiconductor block is made of a p-type thermoelectric conversion material, and has a pillar portion and a connection portion laterally protruding from the pillar portion. In addition, an n-type semiconductor block is made of an n-type thermoelectric conversion material, and has a pillar portion and a connection portion laterally protruding from the pillar portion. The p-type semiconductor block and the n-type semiconductor block are alternately arranged in such a way that the connection portion of the p-type semiconductor block is connected with the pillar portion of the n-type semiconductor block and the connection portion of the n-type semiconductor block is connected with the pillar portion of the p-type semiconductor block. The connection portions and tip-end portions of the pillar portions are made of a thermoelectric conversion material containing metal powder.

Abstract: An object of the invention is to provide an activation control apparatus by which a steam turbine can be activated safely at a high speed in response to a state of a power generation plant.

Abstract: A control parameter optimizing system and an operation optimizing apparatus equipped therewith are provided, the system being applicable to an existing plant without modifying the control panel or equipment of the plant, the system further being capable of optimizing the operation control of the plant in accordance with diverse operational requirements. The system includes an objective function setting section, a plant model, and a control parameter optimizing section. The control parameter optimizing section includes an optimization control parameter selecting section and an optimization control parameter adjusting section. The optimization control parameter selecting section selects as an optimization control parameter the control parameter for optimizing an objective function based on control logic information extracted from a power plant.

Abstract: A thermoelectric conversion device includes a perovskite film over a substrate and formed with first and second electrodes on the perovskite film, wherein the perovskite film includes a domain having a crystal orientation different from a crystal orientation of a crystal that constitutes the perovskite film.