Abstract: An elastic wave device includes a substrate, an elastic wave element, and an exterior resin layer. The substrate includes an outer electrode on one main surface thereof and a first mounting electrode on another main surface thereof. The elastic wave element includes a piezoelectric substrate, a transmission functional electrode, a reception functional electrode, and ground terminals on one main surface of the piezoelectric substrate, and the ground terminals are connected to the first mounting electrode. High-thermal-conductivity conductor layers are provided on another main surface of the piezoelectric substrate, conductor vias penetrate between both main surfaces of the piezoelectric substrate, and the high-thermal-conductivity conductor layers and the ground terminals are connected to each other by the conductor vias.

Abstract: [Problem] Provided is a compound which is useful as an active ingredient of a pharmaceutical composition for treating lung cancer. [Means for Solution] The present inventors have studied a compound useful as an active ingredient of a pharmaceutical composition for treating lung cancer, and as a result, it was found that a quinazoline compound has an excellent G12C mutation KRAS inhibitory activity, and which can be used as a therapeutic agent for lung cancer, and thereby the present invention has been completed. The quinazoline compound of the present invention and a salt thereof may be used as the therapeutic agent for lung cancer.

Abstract: [Problem] Provided is a compound which is useful as an active ingredient of a pharmaceutical composition for treating lung cancer. [Means for Solution] The present inventors have studied a compound useful as an active ingredient of a pharmaceutical composition for treating lung cancer, and as a result, it was found that a quinazoline compound has an excellent G12C mutation KRAS inhibitory activity, and which can be used as a therapeutic agent for lung cancer, and thereby the present invention has been completed. The quinazoline compound of the present invention and a salt thereof may be used as the therapeutic agent for lung cancer.

Abstract: [Problem] Provided is a compound which is useful as an active ingredient of a pharmaceutical composition for treating lung cancer. [Means for Solution] The present inventors have studied a compound useful as an active ingredient of a pharmaceutical composition for treating lung cancer, and as a result, it was found that a quinazoline compound has an excellent G12C mutation KRAS inhibitory activity, and which can be used as a therapeutic agent for lung cancer, and thereby the present invention has been completed. The quinazoline compound of the present invention and a salt thereof may be used as the therapeutic agent for lung cancer.

Abstract: [Problem] Provided is a compound which is useful as an active ingredient of a pharmaceutical composition for treating lung cancer. [Means for Solution] The present inventors have studied a compound useful as an active ingredient of a pharmaceutical composition for treating lung cancer, and as a result, it was found that a quinazoline compound has an excellent G12C mutation KRAS inhibitory activity, and which can be used as a therapeutic agent for lung cancer, and thereby the present invention has been completed. The quinazoline compound of the present invention and a salt thereof may be used as the therapeutic agent for lung cancer.

Abstract: An electronic component device includes a mount substrate including an outer electrode on one principal surface and a mount electrode on another principal surface, at least one substrate component including a terminal electrode on one principal surface, and that is mounted on the mount substrate by joining the terminal electrode to the mount electrode, and a sealing resin layer that is provided on the mount substrate on which the at least one substrate component is mounted. The sealing resin layer includes a region with a large thickness, and a top surface including an inclination.

Abstract: An elastic wave device includes a substrate, an elastic wave element, and an exterior resin layer. The substrate includes an outer electrode on one main surface thereof and a first mounting electrode on another main surface thereof. The elastic wave element includes a piezoelectric substrate, a transmission functional electrode, a reception functional electrode, and ground terminals on one main surface of the piezoelectric substrate, and the ground terminals are connected to the first mounting electrode. High-thermal-conductivity conductor layers are provided on another main surface of the piezoelectric substrate, conductor vias penetrate between both main surfaces of the piezoelectric substrate, and the high-thermal-conductivity conductor layers and the ground terminals are connected to each other by the conductor vias.

Abstract: An elastic wave device includes a sealing member sealing first and second elastic wave elements mounted on the mounting surface and including first and second surfaces, an impression being provided on the second surface. The first elastic wave element includes a first piezoelectric substrate made of LiNbO3, and the second elastic wave element includes a second piezoelectric substrate made of LiNbO3 or LiTaO3. The thickness of the first piezoelectric substrate is larger than the thickness of the second piezoelectric substrate. When a side of the second surface of the sealing member is defined as an upper side and a side of the first surface of the sealing member is defined as a lower side, the thickness of the sealing member located above the first piezoelectric substrate is smaller than the thickness of the sealing member located above the second piezoelectric substrate. The first piezoelectric substrate and the impression do not overlap each other in a plan view from the second surface.

Abstract: An electronic component device includes a mount substrate including an outer electrode on one principal surface and a mount electrode on another principal surface, at least one substrate component including a terminal electrode on one principal surface, and that is mounted on the mount substrate by joining the terminal electrode to the mount electrode, and a sealing resin layer that is provided on the mount substrate on which the at least one substrate component is mounted. The sealing resin layer includes a region with a large thickness, and a top surface including an inclination.

Abstract: An elastic wave device is configured such that a first surface acoustic wave chip including a piezoelectric substrate is mounted on a package board, a center of the first surface acoustic wave chip is shifted from a center of the package board when viewed from above, and a crystal Z-axis orientation of the piezoelectric substrate of the first surface acoustic wave chip is slanted to extend toward an outer side portion from a central portion of the package board as it progresses toward an upper surface from a lower surface of the piezoelectric substrate.

Abstract: A ladder surface acoustic wave filter includes a series arm connecting an input terminal and an output terminal, at least one parallel arm connecting the series arm and a ground terminal, at least one series arm resonator provided in the series arm, and at least two parallel arm resonators provided in at least one parallel arm and connected to each other in series. In the ladder surface acoustic wave filter, a connection point between at least the two parallel resonators connected to each other in series is grounded through an inductor.

Abstract: An elastic wave device is configured such that a first surface acoustic wave chip including a piezoelectric substrate is mounted on a package board, a center of the first surface acoustic wave chip is shifted from a center of the package board when viewed from above, and a crystal Z-axis orientation of the piezoelectric substrate of the first surface acoustic wave chip is slanted to extend toward an outer side portion from a central portion of the package board as it progresses toward an upper surface from a lower surface of the piezoelectric substrate.

Abstract: An antenna branching filter includes an antenna terminal, a first filter circuit with a first pass band, and a second filter circuit with a second pass band that does not include the first pass band and with frequencies higher than those of the first pass band. The antenna terminal, the first filter circuit, and the second filter circuit are connected to each other at a first connection point. The second filter circuit includes longitudinally coupled resonator filter circuits. Resonators are provided between the first connection point and the longitudinally coupled resonator filters. Low-frequency band pass circuits with a stop band in the second pass band are provided between second connection points and the ground potential.

Abstract: An electrophotographic photosensitive drum comprises a cylinder having a photosensitive layer formed thereon, with the cylinder being rotatable about an axis thereof. A driving force transmitting part is securely fixed to one axial end of the cylinder. The driving force transmitting part includes (i) a gear encircling a peripheral portion of the driving force transmitting part and (ii) a projection disposed on a side of the gear opposite from the cylinder, with the projection having a base and a free end. At least a portion of a cross-section of the projection at the base is offset from a corresponding portion of a cross-section of the projection at the free end, as seen in a direction of the axis.

Abstract: A ladder surface acoustic wave filter includes a series arm connecting an input terminal and an output terminal, at least one parallel arm connecting the series arm and a ground terminal, at least one series arm resonator provided in the series arm, and at least two parallel arm resonators provided in at least one parallel arm and connected to each other in series. In the ladder surface acoustic wave filter, a connection point between at least the two parallel resonators connected to each other in series is grounded through an inductor.

Abstract: An electrophotographic photosensitive drum comprises a cylinder having a photosensitive layer formed thereon, with the cylinder being rotatable about an axis thereof. A driving force transmitting part is securely fixed to one axial end of the cylinder. The driving force transmitting part includes (i) a gear encircling a peripheral portion of the driving force transmitting part and (ii) a projection disposed on a side of the gear opposite from the cylinder, with the projection having a base and a free end. At least a portion of a cross-section of the projection at the base is offset from a corresponding portion of a cross-section of the projection at the free end, as seen in a direction of the axis.

Abstract: An electrophotographic photosensitive drum comprises a cylinder having a photosensitive layer formed thereon, with the cylinder being rotatable about an axis thereof. A driving force transmitting part is securely fixed to one axial end of the cylinder. The driving force transmitting part includes (i) a gear encircling a peripheral portion of the driving force transmitting part and (ii) a projection disposed on a side of the gear opposite from the cylinder, with the projection having a base and a free end. At least a portion of a cross-section of the projection at the base is offset from a corresponding portion of a cross-section of the projection at the free end, as seen in a direction of the axis.

Abstract: As a result of studies on compounds having a selective inhibitory activity against 17?HSD type 5, the present inventors have confirmed that a {1-[(indol-2-yl)carbonyl]piperidyl}alkanol derivative has a potent selective inhibitory activity against 17?HSD type 5. The invention has been completed based on these findings. The compound of the present invention can be used as an agent for treating and/or an agent for preventing diseases associated with 17?HSD type 5, such as benign prostatic hyperplasia and prostate cancer, without accompanying adverse effects due to a decrease in testosterone.

Abstract: [Problem] An object of the present invention is to provide a novel anticancer drug which is useful for treating prostate cancer accompanying androgen receptor mutation [Means for Solution] The present inventors conducted thorough research on mutant androgen-related diseases for which the traditional anti-androgen drugs become ineffective. As a result, they found that the compound, which is an active ingredient of the pharmaceutical composition of the present invention, exhibits an inhibitory action against transcriptional activation in a human mutant androgen receptor (AR), and has an excellent antitumor action in a human prostate cancer-bearing mouse, thereby completing the present invention. Accordingly, the compound, which is an active ingredient of the pharmaceutical composition of the present invention, is useful for a series of androgen receptor-related diseases including prostate cancer.

Abstract: There is provided a digital controller which can reduce a variation in output voltage as compared to the conventional digital controller at the time of abrupt changes in load and in input of a power amplifier. The digital controller is built in the power amplifier for supplying an output voltage vo to a load and is equipped with a manipulated variable calculating unit which detects the output voltage vo to calculate a manipulated variable ?1 and a signal generating unit which converts the manipulated variable ?1 into a signal for making the power amplifier operate. A feedforward function from an equivalent disturbance qy caused by the variation in the load is replaced by a feedback function from the output voltage vo and the manipulated variable ?1, thereby allowing a transfer characteristic from the disturbance qy to the output voltage vo to result in a quadratic differential characteristic.