Patents by Inventor Kazuyuki Fujishima

Kazuyuki Fujishima has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • M-substituted benzoic acid derivatives having integrin alpha v beta 3 antagonistic activity
    Publication number: 20050059669
    Abstract: An object of the present invention is to provide m-substituted benzoic acid derivatives having integrin ?v?3 antagonistic activity.
    Type: Application
    Filed: September 21, 2004
    Publication date: March 17, 2005
    Inventors: Keiichi Ajito, Minoru Ishikawa, Dai Kubota, Shoichi Murakami, Mikio Yamamoto, Naokazu Yahata, Kazuyuki Fujishima, Makoto Oyama
  • &OHgr;-amino-&agr;-hydroxycarboxylic acid derivatives having integrin &agr;&ngr;&bgr;3 antagonistic activity
    Patent number: 6750219
    Abstract: An objective of the present invention is to provide highly water-soluble compounds having integrin &agr;v&bgr;3 antagonistic activity.
    Type: Grant
    Filed: February 5, 2002
    Date of Patent: June 15, 2004
    Assignee: Meiji Seika Kaisha, Ltd.
    Inventors: Keiichi Ajito, Naokazu Yahata, Minoru Ishikawa, Dai Kubota, Shoichi Murakami, Mikio Yamamoto, Kazuyuki Fujishima, Shuichi Gomi, Shokichi Ouchi
  • Remedies for reperfusion injury containing integrin alphanubeta 3 antagonist
    Publication number: 20030040531
    Abstract: An objective of the present invention is to provide an agent that is clinically effective in the treatment or prevention of reperfusion injury. The agent for use in the treatment or prevention of reperfusion injury according to the present invention comprises an integrin &agr;v&bgr;3 antagonist, a pharmaceutically acceptable salt thereof, or a solvate thereof as active ingredient.
    Type: Application
    Filed: July 25, 2002
    Publication date: February 27, 2003
    Inventors: Kazuyuki Fujishima, Shoichi Murakami, Mikio Yamamoto, Mitsuhiro Abe, Minoru Ishikawa, Shokichi Ouchi, Keiichi Ajito
  • 5-(4-piperidinyl)dibenzothiazepine derivatives and 5-(4-piperidinyl)dibenzoxazepine derivatives, and antiarrhythmic agents
    Patent number: 6063779
    Abstract: An objective of the present invention is to provide a compound that has antiarrhythmic activity. The present invention provides a compound of formula (I): ##STR1## wherein R.sup.1 and R.sup.2 each represent H, halogen or lower alkyl which may be substituted by halogen; A represents H, C3-6 cycloalkyl, phenyl which may be substituted by halogen, nitro, or lower alkoxy, a 5-membered or 6-membered heterocyclic ring which may contain N and/or S, --NR.sup.3 R.sup.4 (wherein R.sup.3 and R.sup.4 each represent H or lower alkyl which may be substituted by phenyl), or COR.sup.5 (wherein R.sup.5 represents OH, amino or lower alkoxy); Q represents S or O; m represents 0-18; and n represents 0-2, and pharmaceutically acceptable salts and solvates thereof.
    Type: Grant
    Filed: May 15, 1998
    Date of Patent: May 16, 2000
    Assignee: Meiji Seika Kaisha, Ltd.
    Inventors: Kiyoaki Katano, Takahiko Satoh, Tomoko Soneda, Naoko Kamitoh, Kazuyuki Fujishima, Mitsugu Hachisu