Patents by Inventor Kei Kawaguchi
Kei Kawaguchi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11001826Abstract: A composition and method for lowing serum and plasma levels of methionine by oral administration. The composition includes a recombinant methioninase enzyme and a cofactor (pyridoxal-L-phosphate). Methods of use describe methods for treatment of cancer, including malignant melanoma, by oral administration of the methioninase composition. Methods for chronic suppressive therapy of melanoma and other cancers are described. Because reduction of plasma methionine levels is effective in treating other conditions, including diabetes and conditions associated with aging, the use of the methods described herein includes treatment of these and other conditions.Type: GrantFiled: October 19, 2018Date of Patent: May 11, 2021Assignee: ANTICANCER, INC.Inventors: Qinghong Han, Shukuan Li, Yuying Tan, Kei Kawaguchi, Robert M. Hoffman, Sant Chawla
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Publication number: 20190153421Abstract: A composition and method for lowing serum and plasma levels of methionine by oral administration. The composition includes a recombinant methioninase enzyme and a cofactor (pyridoxal-L-phosphate). Methods of use describe methods for treatment of cancer, including malignant melanoma, by oral administration of the methioninase composition. Methods for chronic suppressive therapy of melanoma and other cancers are described. Because reduction of plasma methionine levels is effective in treating other conditions, including diabetes and conditions associated with aging, the use of the methods described herein includes treatment of these and other conditions.Type: ApplicationFiled: October 19, 2018Publication date: May 23, 2019Inventors: Qinghong Han, Shukuan Li, Yuying Tan, Kei Kawaguchi, Robert M. Hoffman, Sant Chawla
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Publication number: 20180236011Abstract: Methods using chemotherapy drugs promote targeting of S. typhimurium A1-R of melanoma, thereby enhancing efficacy against the melanoma PDOX. A metastatic melanoma obtained from the right chest wall of a patient was previously established orthotopically in the right chest wall of nude mice as a patient-derived orthotopic xenograft (PDOX) model. We previously showed that the combination of tumor targeting Salmonella typhimurium A1-R (S. typhimurium A1-R) and chemotherapy was highly effective against the melanoma PDOX. In the present study, we investigated the mechanism of the high efficacy of this combination. Combination therapy significantly increases S. typhimurium A1-R tumor targeting alone (S. typhimurium A1-R+TEM: p<0.01, S. typhimurium A1-R+VEM: p<0.01).Type: ApplicationFiled: February 22, 2018Publication date: August 23, 2018Inventors: Kei Kawaguchi, Robert M. Hoffman
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Patent number: 8942855Abstract: A power distribution system for distributing an electric power charged in a battery to a plurality of dwelling units includes a power generation device which has a independent power generation function and is configured to generate an electric power and charge the battery with at least a part of the electric power thus generated, a first control device having a residual amount measuring unit for measuring a residual amount of the electric power charged in the battery and a plurality of second control devices which are provided in a corresponding relationship with the dwelling units and make communications with the first control device. The first control device is configured to adjust an amount of the electric power supplied from the battery to the dwelling units based on a measurement result of the residual amount measuring unit and information received from each of the second control devices.Type: GrantFiled: October 28, 2010Date of Patent: January 27, 2015Assignee: Panasonic CorporationInventors: Kei Kawaguchi, Hiroaki Koshin
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Publication number: 20120226387Abstract: A power distribution system for distributing an electric power charged in a battery to a plurality of dwelling units includes a power generation device which has a independent power generation function and is configured to generate an electric power and charge the battery with at least a part of the electric power thus generated, a first control device having a residual amount measuring unit for measuring a residual amount of the electric power charged in the battery and a plurality of second control devices which are provided in a corresponding relationship with the dwelling units and make communications with the first control device. The first control device is configured to adjust an amount of the electric power supplied from the battery to the dwelling units based on a measurement result of the residual amount measuring unit and information received from each of the second control devices.Type: ApplicationFiled: October 28, 2010Publication date: September 6, 2012Applicant: Panasonic CorporationInventors: Kei Kawaguchi, Hiroaki Koshin
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Publication number: 20120221491Abstract: In a power interchange system, an electric power generated by a power generation device is interchanged between power consuming dwellings in a multi-family house. Each power consuming dwelling generates the power by using the power generation device and receives a commercial AC power supply via a shared power supply wiring. The amount of electric power supplied to each power consuming dwelling is managed by a power management device. The power management device manages a surplus power amount of one power consuming dwelling and a required electric power amount of another power consuming dwelling and supplies the surplus power from the former power consuming dwelling to the latter power consuming dwelling via the power supply wiring.Type: ApplicationFiled: October 28, 2010Publication date: August 30, 2012Applicant: PANASONIC CORPORATIONInventors: Hiroaki Koshin, Akira Yoshitake, Yuusuke Iwamatsu, Kei Kawaguchi, Takuma Kawasaki
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Patent number: 7297315Abstract: The invention provides a method of recovering a copper component or a manganese component from a cleaning agent containing copper oxide, a cleaning agent containing basic copper carbonate, a cleaning agent containing copper hydroxide, or a cleaning agent containing copper oxide and manganese oxide, the cleaning agents having been used for removing, through contact with a harmful gas, a phosphine contained as a harmful component in the harmful gas. Also, the invention provides a method of recovering a copper component or a manganese component from a cleaning agent containing basic copper carbonate, a cleaning agent containing copper hydroxide, or a cleaning agent containing copper oxide and manganese oxide, the cleaning agents having been used for removing, through contact with a harmful gas, a phosphine contained as a harmful component in the harmful gas.Type: GrantFiled: February 2, 2004Date of Patent: November 20, 2007Assignee: Japan Pionics Co., LtdInventors: Kenji Otsuka, Takashi Shimada, Minoru Osugi, Kei Kawaguchi
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Publication number: 20040151644Abstract: The invention provides a method of recovering a copper component or a manganese component from a cleaning agent containing copper oxide, a cleaning agent containing basic copper carbonate, a cleaning agent containing copper hydroxide, or a cleaning agent containing copper oxide and manganese oxide, the cleaning agents having been used for removing, through contact with a harmful gas, a phosphine contained as a harmful component in the harmful gas. Also, the invention provides a method of recovering a copper component or a manganese component from a cleaning agent containing basic copper carbonate, a cleaning agent containing copper hydroxide, or a cleaning agent containing copper oxide and manganese oxide, the cleaning agents having been used for removing, through contact with a harmful gas, a phosphine contained as a harmful component in the harmful gas.Type: ApplicationFiled: February 2, 2004Publication date: August 5, 2004Inventors: Kenji Otsuka, Takashi Shimada, Minoru Osugi, Kei Kawaguchi
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Patent number: 6716403Abstract: The invention provides a method of recovering a copper component or a manganese component from a cleaning agent containing copper oxide, a cleaning agent containing basic copper carbonate, a cleaning agent containing copper hydroxide, or a cleaning agent containing copper oxide and manganese oxide, the cleaning agents having been used for removing, through contact with a harmful gas, a phosphine contained as a harmful component in the harmful gas. Also, the invention provides a method of recovering a copper component or a manganese component from a cleaning agent containing basic copper carbonate, a cleaning agent containing copper hydroxide, or a cleaning agent containing copper oxide and manganese oxide, the cleaning agents having been used for removing, through contact with a harmful gas, a phosphine contained as a harmful component in the harmful gas.Type: GrantFiled: November 9, 2001Date of Patent: April 6, 2004Assignee: Japan Pionics Co., Ltd.Inventors: Kenji Otsuka, Takashi Shimada, Minoru Osugi, Kei Kawaguchi
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Publication number: 20020084220Abstract: The invention provides a method of recovering a copper component or a manganese component from a cleaning agent containing copper oxide, a cleaning agent containing basic copper carbonate, a cleaning agent containing copper hydroxide, or a cleaning agent containing copper oxide and manganese oxide, the cleaning agents having been used for removing, through contact with a harmful gas, a phosphine contained as a harmful component in the harmful gas. Also, the invention provides a method of recovering a copper component or a manganese component from a cleaning agent containing basic copper carbonate, a cleaning agent containing copper hydroxide, or a cleaning agent containing copper oxide and manganese oxide, the cleaning agents having been used for removing, through contact with a harmful gas, a phosphine contained as a harmful component in the harmful gas.Type: ApplicationFiled: November 9, 2001Publication date: July 4, 2002Inventors: Kenji Otsuka, Takashi Shimada, Minoru Osugi, Kei Kawaguchi