Abstract: The present technology relates to a signal processing device, signal processing method, and program capable of providing a higher realistic feeling. A signal processing device includes: an acquisition unit that acquires audio data of an audio object and metadata including position information indicating a position of the audio object and direction information indicating a direction of the audio object; and a signal generation unit that generates a reproduction signal for reproducing a sound of the audio object at a listening position on the basis of listening position information indicating the listening position, listener direction information indicating a direction of a listener at the listening position, the position information, the direction information, and the audio data. The present technology is applicable to a transmission reproduction system.

Abstract: The present invention provides a graphene grid that can suppress or prevent uneven distribution, uneven orientation, and the like of a structural analysis target substance, and can capture the structural analysis target substance with high efficiency and analyze the structural analysis target substance with high resolution, in a structural analysis by cryo-electron microscopy. A graphene grid of the present invention has a graphene surface into which a functional group is introduced.