Patents by Inventor Keith Bonin
Keith Bonin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11883040Abstract: Surgical procedures, tools and implants are disclosed for both conventional and reverse shoulder implant surgeries. The improved procedures, tools and implants relate to humeral head resurfacing, humeral head resection for standard implants, humeral head resection for reverse shoulder implants, glenoid resurfacing for standard shoulder implants and glenoid resurfacing for reverse shoulder implants. 3D scans and x-rays are used to develop virtual models of the patient anatomy, identify patient specific landmarks for anchoring guide wire installation blocks, templates and drill guides. 3D scans are also used to design patient specific tools and implants for the shoulder implant procedures and to pre-operatively determine the appropriate inclination and retroversion angles.Type: GrantFiled: July 13, 2020Date of Patent: January 30, 2024Assignee: Smith and Nephew, Inc.Inventors: Henry Keith Bonin, Jr., David L. Brumfield, Raymond H. Roberson, Jr.
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Publication number: 20200405330Abstract: Surgical procedures, tools and implants are disclosed for both conventional and reverse shoulder implant surgeries. The improved procedures, tools and implants relate to humeral head resurfacing, humeral head resection for standard implants, humeral head resection for reverse shoulder implants, glenoid resurfacing for standard shoulder implants and glenoid resurfacing for reverse shoulder implants. 3D scans and x-rays are used to develop virtual models of the patient anatomy, identify patient specific landmarks for anchoring guide wire installation blocks, templates and drill guides. 3D scans are also used to design patient specific tools and implants for the shoulder implant procedures and to pre-operatively determine the appropriate inclination and retroversion angles.Type: ApplicationFiled: July 13, 2020Publication date: December 31, 2020Inventors: Henry Keith BONIN, JR., David L. BRUMFIELD, Raymond H. ROBERSON, JR.
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Patent number: 10842512Abstract: Surgical procedures, tools and implants are disclosed for both conventional and reverse shoulder implant surgeries. The improved procedures, tools and implants relate to humeral head resurfacing, humeral head resection for standard implants, humeral head resection for reverse shoulder implants, glenoid resurfacing for standard shoulder implants and glenoid resurfacing for reverse shoulder implants. 3D scans and x-rays are used to develop virtual models of the patient anatomy, identify patient specific landmarks for anchoring guide wire installation blocks, templates and drill guides. 3D scans are also used to design patient specific tools and implants for the shoulder implant procedures and to pre-operatively determine the appropriate inclination and retroversion angles.Type: GrantFiled: September 12, 2019Date of Patent: November 24, 2020Assignee: Smith & Nephew, Inc.Inventors: Henry Keith Bonin, Jr., David L. Brumfield, Raymond H. Roberson, Jr.
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Publication number: 20200015830Abstract: Surgical procedures, tools and implants are disclosed for both conventional and reverse shoulder implant surgeries. The improved procedures, tools and implants relate to humeral head resurfacing, humeral head resection for standard implants, humeral head resection for reverse shoulder implants, glenoid resurfacing for standard shoulder implants and glenoid resurfacing for reverse shoulder implants. 3D scans and x-rays are used to develop virtual models of the patient anatomy, identify patient specific landmarks for anchoring guide wire installation blocks, templates and drill guides. 3D scans are also used to design patient specific tools and implants for the shoulder implant procedures and to pre-operatively determine the appropriate inclination and retroversion angles.Type: ApplicationFiled: September 12, 2019Publication date: January 16, 2020Inventors: Henry Keith Bonin, Jr., David L. Brumfield, Raymond H. Roberson, Jr.
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Publication number: 20190353644Abstract: The invention relates to methods for quantitating cell (e.g., epithelial cell) apical-basal polarity in three-dimensional multi-cell structures. The invention further relates to methods of using quantitation assays to screen for agents that modulate polarity, assess the risk of developing cancer, and monitor the effectiveness of cancer prevention programs.Type: ApplicationFiled: May 17, 2019Publication date: November 21, 2019Inventors: Pierre-Alexandre Vidi, Keith Bonin
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Patent number: 10481153Abstract: Methods, systems, devices and apparatus for use in screening and/or selecting a library of nucleic acid molecules and/or nucleic acid tagged or encoded molecules for binding to or interaction with a target molecule or substance (e.g., for use in new compound or drug discovery) are described. In some embodiments the device comprises: (a) a spatially addressable array, said array comprising a plurality of separate and discrete locations thereon; (b) a plurality of different oligomers operably connected to said spatially addressable array at different ones of said separate and discrete locations; (c) a tag sequence which is complementary to, and is hybridized to, each of said oligomers; and (d) a candidate chemical operably connected to each of said tag sequences, wherein each of said discrete locations is a unique identifier for its corresponding oligomer; and wherein said tag sequence is a unique identifier for its connected candidate chemical.Type: GrantFiled: July 19, 2017Date of Patent: November 19, 2019Assignees: Wake Forest University, NanoMedica LLCInventors: Keith Bonin, Jed C. Macosko, Jason Gagliano, Martin Guthold, Roger Cubicciotti
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Patent number: 10426495Abstract: Surgical procedures, tools and implants are disclosed for both conventional and reverse shoulder implant surgeries. The improved procedures, tools and implants relate to humeral head resurfacing, humeral head resection for standard implants, humeral head resection for reverse shoulder implants, glenoid resurfacing for standard shoulder implants and glenoid resurfacing for reverse shoulder implants. 3D scans and x-rays are used to develop virtual models of the patient anatomy, identify patient specific landmarks for anchoring guide wire installation blocks, templates and drill guides. 3D scans are also used to design patient specific tools and implants for the shoulder implant procedures and to pre-operatively determine the appropriate inclination and retroversion angles.Type: GrantFiled: January 12, 2016Date of Patent: October 1, 2019Assignee: Smith & Nephew, Inc.Inventors: Henry Keith Bonin, Jr., David L Brumfield, Raymond H. Roberson, Jr.
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Patent number: 9918854Abstract: A method of aligning implant components includes placing a first implant component in bone, followed by: coupling a first intermediate member to the first implant component; coupling a first alignment member to the first intermediate member; rotating the members as a unit to place the first intermediate member in an alignment position; removing the first alignment member from the first intermediate member; coupling a second alignment member to a second intermediate member; coupling the second intermediate member to the first intermediate member and rotating the second alignment member and the second intermediate member as a unit relative to the first intermediate member to provide a desired orientation of the second intermediate member. An alignment system for aligning first and second members includes a first alignment member having an offset channel dimensioned to receive the first member, and a second alignment member having a channel dimensioned to receive the second member.Type: GrantFiled: March 15, 2012Date of Patent: March 20, 2018Assignee: Smith & Nephew, Inc.Inventors: Henry Keith Bonin, Jr., David Edward Chreene, Alexander Iwan Seidl, Claude Mathieu, Daniel Zimmerman, Francis X. Mendoza
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Publication number: 20170322206Abstract: Methods, systems, devices and apparatus for use in screening and/or selecting a library of nucleic acid molecules and/or nucleic acid tagged or encoded molecules for binding to or interaction with a target molecule or substance (e.g., for use in new compound or drug discovery) are described. In some embodiments the device comprises: (a) a spatially addressable array, said array comprising a plurality of separate and discrete locations thereon; (b) a plurality of different oligomers operably connected to said spatially addressable array at different ones of said separate and discrete locations; (c) a tag sequence which is complementary to, and is hybridized to, each of said oligomers; and (d) a candidate chemical operably connected to each of said tag sequences, wherein each of said discrete locations is a unique identifier for its corresponding oligomer; and wherein said tag sequence is a unique identifier for its connected candidate chemical.Type: ApplicationFiled: July 19, 2017Publication date: November 9, 2017Inventors: Keith Bonin, Jed C. Macosko, Jason Gagliano, Martin Guthold, Roger Cubicciotti
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Patent number: 9746466Abstract: Methods, systems, devices and apparatus for use in screening and/or selecting a library of nucleic acid molecules and/or nucleic acid tagged or encoded molecules for binding to or interaction with a target molecule or substance (e.g., for use in new compound or drug discovery) are described. In some embodiments the device comprises: (a) a spatially addressable array, said array comprising a plurality of separate and discrete locations thereon; (b) a plurality of different oligomers operably connected to said spatially addressable array at different ones of said separate and discrete locations; (c) a tag sequence which is complementary to, and is hybridized to, each of said oligomers; and (d) a candidate chemical operably connected to each of said tag sequences, wherein each of said discrete locations is a unique identifier for its corresponding oligomer; and wherein said tag sequence is a unique identifier for its connected candidate chemical.Type: GrantFiled: December 21, 2012Date of Patent: August 29, 2017Assignees: NanoMedica LLC, Wake Forest UniversityInventors: Keith Bonin, Jed C. Mocosko, Jason Gagliano, Martin Guthold, Roger Cubicciotti
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Publication number: 20160120555Abstract: Surgical procedures, tools and implants are disclosed for both conventional and reverse shoulder implant surgeries. The improved procedures, tools and implants relate to humeral head resurfacing, humeral head resection for standard implants, humeral head resection for reverse shoulder implants, glenoid resurfacing for standard shoulder implants and glenoid resurfacing for reverse shoulder implants, 3D scans and x-rays are used to develop virtual models of the patient anatomy, identify patient specific landmarks for anchoring guide wire installation blocks, templates and drill guides. 3D scans are also used to design patient specific tools and implants for the shoulder implant procedures and to pre-operatively determine the appropriate inclination and retroversion angles.Type: ApplicationFiled: January 12, 2016Publication date: May 5, 2016Inventors: Henry Keith Bonin, JR., David L. Brumfield, Raymond H. Roberson, JR.
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Patent number: 9232955Abstract: Surgical procedures, tools and implants are disclosed for both conventional and reverse shoulder implant surgeries. The improved procedures, tools and implants relate to humeral head resurfacing, humeral head resection for standard implants, humeral head resection for reverse shoulder implants, glenoid resurfacing for standard shoulder implants and glenoid resurfacing for reverse shoulder implants. 3D scans and x-rays are used to develop virtual models of the patient anatomy, identify patient specific landmarks for anchoring guide wire installation blocks, templates and drill guides. 3D scans are also used to design patient specific tools and implants for the shoulder implant procedures and to pre-operatively determine the appropriate inclination and retroversion angles.Type: GrantFiled: July 12, 2011Date of Patent: January 12, 2016Assignee: Smith & Nephew, Inc.Inventors: Henry Keith Bonin, Jr., David L. Brumfield, Raymond H. Roberson, Jr.
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Publication number: 20150005178Abstract: Methods, systems, devices and apparatus for use in screening and/or selecting a library of nucleic acid molecules and/or nucleic acid tagged or encoded molecules for binding to or interaction with a target molecule or substance (e.g., for use in new compound or drug discovery) are described. In some embodiments the device comprises: (a) a spatially addressable array, said array comprising a plurality of separate and discrete locations thereon; (b) a plurality of different oligomers operably connected to said spatially addressable array at different ones of said separate and discrete locations; (c) a tag sequence which is complementary to, and is hybridized to, each of said oligomers; and (d) a candidate chemical operably connected to each of said tag sequences, wherein each of said discrete locations is a unique identifier for its corresponding oligomer; and wherein said tag sequence is a unique identifier for its connected candidate chemical.Type: ApplicationFiled: December 21, 2012Publication date: January 1, 2015Applicants: Wake Forest University, NanoMedica LLCInventors: Keith Bonin, Jed C. Macosko, Jason Gagliano, Martin Guthold, Roger Cubicciotti
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Publication number: 20140222153Abstract: A method of aligning implant components includes placing a first implant component in bone, followed by: coupling a first intermediate member to the first implant component; coupling a first alignment member to the first intermediate member; rotating the members as a unit to place the first intermediate member in an alignment position; removing the first alignment member from the first intermediate member; coupling a second alignment member to a second intermediate member; coupling the second intermediate member to the first intermediate member and rotating the second alignment member and the second intermediate member as a unit relative to the first intermediate member to provide a desired orientation of the second intermediate member. An alignment system for aligning first and second members includes a first alignment member having an offset channel dimensioned to receive the first member, and a second alignment member having a channel dimensioned to receive the second member.Type: ApplicationFiled: March 15, 2012Publication date: August 7, 2014Inventors: Henry Keith Bonin, JR., David Edward Chreene, Alexander Iwan Seidl, Claude Mathieu, Daniel Zimmerman, Francis X. Mendoza
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Patent number: 8657882Abstract: The present application is directed to an expandable intervertebral device. One context in which the device may be used is a corpectomy procedure to replace one or more vertebral members. The device is adjustable between a first orientation with a first overall height, and a second orientation with a second overall height. The device generally includes an inner member, an outer member, and a gear. Rotation of the gear causes relative movement between the inner and outer members to move between the first and second orientations and adjust the overall height.Type: GrantFiled: April 24, 2006Date of Patent: February 25, 2014Assignee: Warsaw Orthopedic, Inc.Inventor: Henry Keith Bonin, Jr.
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Publication number: 20140012266Abstract: Surgical procedures, tools and implants are disclosed for both conventional and reverse shoulder implant surgeries. The improved procedures, tools and implants relate to humeral head resurfacing, humeral head resection for standard implants, humeral head resection for reverse shoulder implants, glenoid resurfacing for standard shoulder implants and glenoid resurfacing for reverse shoulder implants. 3D scans and x-rays are used to develop virtual models of the patient anatomy, identify patient specific landmarks for anchoring guide wire installation blocks, templates and drill guides. 3D scans are also used to design patient specific tools and implants for the shoulder implant procedures and to pre-operatively determine the appropriate inclination and retroversion angles.Type: ApplicationFiled: July 12, 2011Publication date: January 9, 2014Applicant: SMITH & NEPHEW, INC.Inventors: Henry Keith Bonin, JR., David L. Brumfield, Raymond H. Roberson, JR.
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Patent number: 8617215Abstract: An elongated connecting element and system for dynamic spinal stabilization is disclosed. The connecting element and system provides for resistance to shear forces applied to the connecting element as well as provides for rotational stability of a resilient intermediate element disposed between two end members.Type: GrantFiled: May 14, 2008Date of Patent: December 31, 2013Assignee: Warsaw Orthopedic, Inc.Inventors: Greg C. Marik, Carlos E. Gil, Henry Keith Bonin, Jr.
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Patent number: 8430912Abstract: A spinal stabilization rod includes a first rod portion having a proximal end and a distal end and having a first cross-sectional area. The second rod portion extends from the distal end of the first rod portion and has a second minimum cross-sectional area smaller than the first cross-sectional area. The second rod portion is formed of a first material and a different second material, with the first material being more resistant in shear than the second material. The implant also includes a slider portion disposed about and movable relative to the second rod portion.Type: GrantFiled: May 5, 2008Date of Patent: April 30, 2013Assignee: Warsaw Orthopedic, Inc.Inventors: Michael S. Veldman, Henry Keith Bonin, Jr.
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Patent number: 8425601Abstract: The present application is directed to methods and devices that provide for asymmetrical movement of vertebral members. In one embodiment, first and second anchors connect the rod to the vertebral members. The rod may be fixedly connected to the first anchor, and movably connected to the second anchor. A limiting device may be positioned on one or both sides of the second anchor. The limiting device or devices control an extent of movement between the rod and the second anchor during vertebral motion. In one embodiment, the device controls an amount of flexion and extension of the vertebral members.Type: GrantFiled: September 11, 2006Date of Patent: April 23, 2013Assignee: Warsaw Orthopedic, Inc.Inventors: Aurelien Bruneau, Thomas A. Carls, Eric C. Lange, John Durward Pond, Jr., Kent M. Anderson, Henry Keith Bonin, Jr., Jonathan M. Dewey
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Patent number: 8211146Abstract: An implantable device includes a first arm member, a second arm member, a compressible member disposed between and coupled to the first arm member and the second arm member, and a tensioning member coupled to the first arm member and the second arm member. Wherein upon moving the first arm member toward the second arm member the tensioning member translates within the first arm member.Type: GrantFiled: July 3, 2008Date of Patent: July 3, 2012Assignee: Warsaw OrthopedicInventors: Jeffrey R. Justis, Jonathan M. Dewey, Henry Keith Bonin, Jr., Christopher M. Patterson, Dimitri K. Protopsaltis