Abstract: A camera capable of quickly updating a region of interest (ROI) in its sensor array is provided. The camera is configured to image individual scan lines of a scan imager created as a scan beam is scanned across a subject. A different ROI is defined for each scan line to be imaged. To achieve this, a table of ROI-defining entries is loaded into the camera prior to imaging the scan lines. The ROI-defining entries are used to update the sensor's ROI during the camera's Frame-Overhead-Time. In this manner, the ROI is changed in between the imaging of consecutive scans lines.

Abstract: A camera capable of quickly updating a region of interest (ROI) in its sensor array is provided. The camera is configured to image individual scan lines of a scan imager created as a scan beam is scanned across a subject. A different ROI is defined for each scan line to be imaged. To achieve this, a table of ROI-defining entries is loaded into the camera prior to imaging the scan lines. The ROI-defining entries are used to update the sensor's ROI during the camera's Frame-Overhead-Time. In this manner, the ROI is changed in between the imaging of consecutive scans lines.

Abstract: Methods to create montages of wide-field fundus images, while correcting for the projective distortion inherent to an imaging system are described. The methods use specific knowledge of the imaging geometry of the particular imaging system to map the fundus images onto a set of 3D ray vectors, which allows them to be stitched together efficiently and precisely. After co-aligning the images using feature detection and matching, the registered images are projected back into 2D to generate the final montaged image. The method could be used on any type of wide-field fundus images including, but not limited to, those generated from optical coherence tomography, optical coherence tomography angiography, and broad-line fundus imaging systems.

Abstract: Methods to create montages of wide-field fundus images, while correcting for the projective distortion inherent to an imaging system are described. The methods use specific knowledge of the imaging geometry of the particular imaging system to map the fundus images onto a set of 3D ray vectors, which allows them to be stitched together efficiently and precisely. After co-aligning the images using feature detection and matching, the registered images are projected back into 2D to generate the final montaged image. The method could be used on any type of wide-field fundus images including, but not limited to, those generated from optical coherence tomography, optical coherence tomography angiography, and broad-line fundus imaging systems.

Abstract: An image data set acquired by an optical coherence tomography (OCT) system is corrected for effects due to motion of the sample. A first set of A-scans is acquired within a time short enough to avoid any significant motion of the sample. A second more extensive set of A-scans is acquired over an overlapping region on the sample. Significant sample motion may occur during acquisition of the second set. A-scans from the first set are matched with A-scans from the second set, based on similarity between the longitudinal optical scattering profiles they contain. Such matched pairs of A-scans are likely to correspond to the same region in the sample. Comparison of the OCT scanner coordinates that produced each A-scan in a matching pair, in conjunction with any shift in the longitudinal scattering profiles between the pair of A-scans, reveals the displacement of the sample between acquisition of the first and second A-scans in the pair.

Abstract: An improved fundus imager for recording an image of a fundus of an eye is described. A line from a point on the fundus at a center of the image to a center of a pupil of the eye defines an axis. The fundus imager includes at least a source of illuminating light, optics for directing the illuminating light to the fundus of the eye, and a rotating element for rotating the illuminating about the axis such that the illuminating light illuminates the fundus at a plurality of locations around the axis. In a preferred embodiment of the present application, the rotating element is a rotating slit-shaped illumination aperture. In an alternate embodiment, the rotating element is a Dove prism for rotating the illuminating light on the fundus.

Abstract: An image data set acquired by an optical coherence tomography (OCT) system is corrected for effects due to motion of the sample. A first set of A-scans is acquired within a time short enough to avoid any significant motion of the sample. A second more extensive set of A-scans is acquired over an overlapping region on the sample. Significant sample motion may occur during acquisition of the second set. A-scans from the first set are matched with A-scans from the second set, based on similarity between the longitudinal optical scattering profiles they contain. Such matched pairs of A-scans are likely to correspond to the same region in the sample. Comparison of the OCT scanner coordinates that produced each A-scan in a matching pair, in conjunction with any shift in the longitudinal scattering profiles between the pair of A-scans, reveals the displacement of the sample between acquisition of the first and second A-scans in the pair.

Abstract: An image data set acquired by an optical coherence tomography (OCT) system is corrected for effects due to motion of the sample. A first set of A-scans is acquired within a time short enough to avoid any significant motion of the sample. A second more extensive set of A-scans is acquired over an overlapping region on the sample. Significant sample motion may occur during acquisition of the second set. A-scans from the first set are matched with A-scans from the second set, based on similarity between the longitudinal optical scattering profiles they contain. Such matched pairs of A-scans are likely to correspond to the same region in the sample. Comparison of the OCT scanner coordinates that produced each A-scan in a matching pair, in conjunction with any shift in the longitudinal scattering profiles between the pair of A-scans, reveals the displacement of the sample between acquisition of the first and second A-scans in the pair.

Abstract: A line scan imager is used to determine the motion of a subject. Each line of image data from the line scan imager is compared with a reference image. The location of a matching line in the reference image reveals the displacement of the subject. The current subject displacement can be determined based on each line of image data. The resulting displacement information can be used to correctly place other optical beams on the subject. The method can be applied to tracking the human eye to facilitate measurement, imaging, or treatment with a beam of optical radiation.

Abstract: The invention relates generally to optical tomographic imaging and in particular to systems and methods for adapting the resolution of imaging. One embodiment of the present invention is an apparatus for optical coherence tomography imaging, characterized by its ability to vary the axial resolution and scanning speed during imaging.

Abstract: An image data set acquired by an optical coherence tomography (OCT) system is corrected for effects due to motion of the sample. A first set of A-scans is acquired within a time short enough to avoid any significant motion of the sample. A second more extensive set of A-scans is acquired over an overlapping region on the sample. Significant sample motion may occur during acquisition of the second set. A-scans from the first set are matched with A-scans from the second set, based on similarity between the longitudinal optical scattering profiles they contain. Such matched pairs of A-scans are likely to correspond to the same region in the sample. Comparison of the OCT scanner coordinates that produced each A-scan in a matching pair, in conjunction with any shift in the longitudinal scattering profiles between the pair of A-scans, reveals the displacement of the sample between acquisition of the first and second A-scans in the pair.

Abstract: A line scan imager is used to determine the motion of a subject. Each line of image data from the line scan imager is compared with a reference image. The location of a matching line in the reference image reveals the displacement of the subject. The current subject displacement can be determined based on each line of image data. The resulting displacement information can be used to correctly place other optical beams on the subject. The method can be applied to tracking the human eye to facilitate measurement, imaging, or treatment with a beam of optical radiation.

Abstract: The invention relates generally to optical tomographic imaging and in particular to systems and methods for adapting the resolution of imaging. One embodiment of the present invention is an apparatus for optical coherence tomography imaging, characterized by its ability to vary the axial resolution and scanning speed during imaging.

Abstract: An image data set acquired by an optical coherence tomography (OCT) system is corrected for effects due to motion of the sample. A first set of A-scans is acquired within a time short enough to avoid any significant motion of the sample. A second more extensive set of A-scans is acquired over an overlapping region on the sample. A-scans from the first set are matched with A-scans from the second set. Comparison of the OCT scanner coordinates that produced each A-scan in a matching pair reveals the displacement of the sample between acquisition of the first and second A-scans in the pair. Estimates of the sample displacement are used to correct the transverse and longitudinal coordinates of the A-scans in the second set, to form a motion-corrected OCT data set.

Abstract: A line scan imager is used to determine the motion of a subject. Each line of image data from the line scan imager is compared with a reference image. The location of a matching line in the reference image reveals the displacement of the subject. The current subject displacement can be determined based on each line of image data. The resulting displacement information can be used to correctly place other optical beams on the subject. The method can be applied to tracking the human eye to facilitate measurement, imaging, or treatment with a beam of optical radiation.

Abstract: The invention relates generally to optical tomographic imaging and in particular to systems and methods for adapting the resolution of imaging. One embodiment of the present invention is an apparatus for optical coherence tomography imaging, characterized by its ability to vary the axial resolution and scanning speed during imaging.

Abstract: The invention relates generally to optical tomographic imaging and in particular to systems and methods for adapting the resolution of imaging. One embodiment of the present invention is an apparatus for optical coherence tomography imaging, characterized by its ability to vary the axial resolution and scanning speed during imaging.

Abstract: A line scan imager is used to determine the motion of a subject. Each line of image data from the line scan imager is compared with a reference image. The location of a matching line in the reference image reveals the displacement of the subject. The current subject displacement can be determined based on each line of image data. The resulting displacement information can be used to correctly place other optical beams on the subject. The method can be applied to tracking the human eye to facilitate measurement, imaging, or treatment with a beam of optical radiation.

Abstract: An image data set acquired by an optical coherence tomography (OCT) system is corrected for effects due to motion of the sample. A first set of A-scans is acquired within a time short enough to avoid any significant motion of the sample. A second more extensive set of A-scans is acquired over an overlapping region on the sample. A-scans from the first set are matched with A-scans from the second set. Comparison of the OCT scanner coordinates that produced each A-scan in a matching pair reveals the displacement of the sample between acquisition of the first and second A-scans in the pair. Estimates of the sample displacement are used to correct the transverse and longitudinal coordinates of the A-scans in the second set, to form a motion-corrected OCT data set.

Abstract: A line scan imager is used to determine the motion of a subject. Each line of image data from the line scan imager is compared with a reference image. The location of a matching line in the reference image reveals the displacement of the subject. The current subject displacement can be determined based on each line of image data. The resulting displacement information can be used to correctly place other optical beams on the subject. The method can be applied to tracking the human eye to facilitate measurement, imaging, or treatment with a beam of optical radiation.