Abstract: A “one-step” process for production of peptides and other organic molecules which are both esters and also acetylated forms of the desired molecule. The ester may be a mono-ester, di-ester, or another poly-ester, complexed with a molecule for protecting the organic molecules in the digestive tract. The method allows simple adjustment of the delivery properties of the peptides produced, in particular adjustment or addition of lipiphilic tendencies. A therapeutic or nutrient made by this method comprises acetylated organic molecule esters, in particular an acetylated peptide ester or even an acetylated amino acid ester and demonstrates improved metabolic properties leading to increased efficiency for therapeutic and cosmetic purposes including oral, transdermal, sublingual, buccal, and topical administration.

Abstract: A “one-step” process for production of peptides and other organic molecules which are both esters and also acetylated forms of the desired molecule. The ester may be a mono-ester, di-ester, or another poly-ester, complexed with a molecule for protecting the organic molecules in the digestive tract. The method allows simple adjustment of the delivery properties of the peptides produced, in particular adjustment or addition of lipiphilic tendencies. A therapeutic or nutrient made by this method comprises acetylated organic molecule esters, in particular an acetylated peptide ester or even an acetylated amino acid ester and demonstrates improved metabolic properties leading to increased efficiency for therapeutic and cosmetic purposes including oral, transdermal, sublingual, buccal, and topical administration.

Abstract: A glutathione composition for lightening or protecting skin is disclosed together with a method for lightening skin or protecting the skin from the effects of ultraviolet radiation is accomplished by administering glutathione to the skin. The glutathione may be glutathione modified with at least one fatty acid or the glutathione molecule is acetylated/esterified. In instances where it is acetylated/esterified, it may optionally be associated with cyclodextrin.

Abstract: Adding fatty acids to agents enhances deliverability of the antioxidant, making the agent less likely to be degraded prior to intercellular delivery. Additionally, adding fatty acids to agents provides a time lapse-type mechanism to the agents. Fatty acid modified agents are made with a novel process in aqueous solution, reducing the need to use organic solvents. Agents that can be modified as disclosed herein include nearly any biological molecule that have hydroxyl, amine, or sulphydryl sites, including antioxidants, such as glutathione and polyphenols (e.g., ECGC, curcumin, or resveratol), saccharides, such as glucosamine, and other glycans.

Abstract: Stem cell secretions are derived from epithelial cells conditioned media. The stem cell secretions are then applied topically, orally, or rectally, etc., to derive health benefits from the growth factors and other molecules comprising the stem cell secretion. The stem cell secretion may optionally be modified by covalently bonding fatty acids to protect the molecules through the delivery process and to make them more readily available to cells.

Abstract: The invention provides peptides and compositions comprising them for the treatment of hair loss and excess hair as well as psoriasis. Methods of preparing the peptides as well as methods for their use are also provided as well as methods of assaying them for inverse agonist and agonist activities. The compounds of the present invention may be topically administered to areas of skin requiring such treatment.