Abstract: In one aspect, the present disclosure describes new estrogen receptor-related orphan receptor (EER) inverse agonist compounds. Also described are pharmaceutical formulations, methods of synthesis and uses thereof.

Abstract: A combustor dome may be formed by way of additive layer manufacturing. The combustor dome may further include a raised outer surface and a recessed outer surface on a hot side of the combustor dome. The recessed outer surfaces may be closer to the cold side than the raised outer surfaces. The combustor dome may include a shadow surface defined between the raised outer surface and recessed outer surface. The shadow surface may define a corresponding cooling outlet in fluid communication with an internal cooling channel defined inside of the combustor dome. The cooling outlet may release air from the internal cooling channel to the hot axial side of the combustor dome.

Abstract: A combustion section of a gas turbine engine may include a cassette configured to couple to an annular combustor dome arranged around a flow path for the gas turbine engine. The annular combustor dome may include a dome wall comprising a plurality of inlets configured to receive compressed air for a combustion chamber located downstream, relative to the flow path, from the annular combustor dome. The cassette may include a combustor wall extended away from the dome wall in a downstream direction. The cassette may further include a cowl integral to the combustor wall. At least a portion of the cowl may extend away from the dome wall in an upstream direction relative to the flow path. The cowl may receive compressed air from a diffusor and guide the compressed air to a space upstream from the inlets, relative to the flow path.

Abstract: In one aspect, the present disclosure describes new estrogen receptor-related orphan receptor (EER) inverse agonist compounds. Also described are pharmaceutical formulations, methods of synthesis and uses thereof.

Abstract: A combustor dome may be formed by way of additive layer manufacturing. The combustor dome may further include a raised outer surface and a recessed outer surface on a hot side of the combustor dome. The recessed outer surfaces may be closer to the cold side than the raised outer surfaces. The combustor dome may include a shadow surface defined between the raised outer surface and recessed outer surface. The shadow surface may define a corresponding cooling outlet in fluid communication with an internal cooling channel defined inside of the combustor dome. The cooling outlet may release air from the internal cooling channel to the hot axial side of the combustor dome.

Abstract: A combustion section of a gas turbine engine may include a cassette configured to couple to an annular combustor dome arranged around a flow path for the gas turbine engine. The annular combustor dome may include a dome wall comprising a plurality of inlets configured to receive compressed air for a combustion chamber located downstream, relative to the flow path, from the annular combustor dome. The cassette may include a combustor wall extended away from the dome wall in a downstream direction. The cassette may further include a cowl integral to the combustor wall. At least a portion of the cowl may extend away from the dome wall in an upstream direction relative to the flow path. The cowl may receive compressed air from a diffusor and guide the compressed air to a space upstream from the inlets, relative to the flow path.

Abstract: An afterburner for use with a gas turbine engine includes a plurality of vanes distributed downstream of a turbine of the gas turbine engine. The vanes can include one or more exit apertures through which hot combustion flow from a pilot can be injected. The exit apertures can be protrusions or slots in some forms. In some embodiments, cooling passages are arranged around the exit apertures. An upstream vane portion can be positioned to inject fuel to be combusted via interaction with hot flow that is discharged through the exit apertures.

Abstract: An afterburner is disclosed for use with a gas turbine engine and, in one form, is structured to receive a bypass air. The afterburner can be situated in a bypass duct and can be a toroidal combustor or a can combustor. In one embodiment, the afterburner includes a combustor arranged to receive bypass air and a plurality of vanes distributed downstream of a turbine of the gas turbine engine. The vanes can include one or more exit apertures through which hot combustion flow from the afterburner combustor can be injected. The exit apertures can be protrusions or slots in some forms. In one embodiment, a cooling passage is arranged around the exit apertures. An upstream vane portion can be positioned to inject fuel to be combusted via interaction with hot flow that is discharged through the exit apertures.

Abstract: An afterburner for use with a gas turbine engine includes a plurality of vanes distributed downstream of a turbine of the gas turbine engine. The vanes can include one or more exit apertures through which hot combustion flow from a pilot can be injected. The exit apertures can be protrusions or slots in some forms. In some embodiments, cooling passages are arranged around the exit apertures. An upstream vane portion can be positioned to inject fuel to be combusted via interaction with hot flow that is discharged through the exit apertures.

Abstract: Reduction of crosstalk between induction heating coils in an induction heating apparatus and particularly to reduction of crosstalk in a multi-zone induction heating system provides greater reliability for the power modules.

Abstract: An afterburner is disclosed for use with a gas turbine engine and, in one form, is structured to receive a bypass air. The afterburner can be situated in a bypass duct and can be a toroidal combustor or a can combustor. In one embodiment, the afterburner includes a combustor arranged to receive bypass air and a plurality of vanes distributed downstream of a turbine of the gas turbine engine. The vanes can include one or more exit apertures through which hot combustion flow from the afterburner combustor can be injected. The exit apertures can be protrusions or slots in some forms. In one embodiment, a cooling passage is arranged around the exit apertures. An upstream vane portion can be positioned to inject fuel to be combusted via interaction with hot flow that is discharged through the exit apertures.

Abstract: A modified communication cable and terminal connector provides an effective combination to accommodate the transmission of signals over fiber optic conductors. The terminal connector includes a light transmitter, a light receiver and interface circuitry such that the connector exchanges signals over electrical conductors. The connector receives and engages fiber optic conductors and an alignment ferrule completes a connection with a fixed lens of the transmitter or receiver. The particular arrangement requires cleaving of the fiber optic conductors but avoids steps such as polishing and gluing.

Abstract: A series-parallel resonant inverter inductively couples a switchable DC power source, which has a positive reference voltage node, a negative voltage reference node and a common reference node to a load. The load comprises a parallel resonator that is inductively coupled to the work piece and a series resonator. The series and parallel resonators each preferably has impedance, where the series circuit's impedance is greater than the impedance of the parallel circuit. The series resonator could include a high impedance inductor and a DC blocking capacitor in series with each other.

Abstract: Reduction of crosstalk between induction heating coils in an induction heating apparatus and particularly to reduction of crosstalk in a multi-zone induction heating system provides greater reliability for the power modules.

Abstract: A system includes a roll formed from a conductive material, where the roll is configured to rotate about an axis and has a direction of rotation. The system also includes multiple induction heating workcoils each configured to induce one or more magnetic fluxes within the roll to generate one or more electrical currents within the roll. Each induction heating workcoil can be oriented so that a mean magnetic flux induced by the workcoil is oblique to the roll's direction of rotation. Each of the induction heating workcoils could represent an unbalanced induction heating workcoil, or each of the induction heating workcoils could include a core having a shape that is not substantially dependent on the roll's diameter.

Abstract: A system includes a roll formed from a conductive material, where the roll is configured to rotate about an axis. The system also includes an induction heating workcoil configured to generate currents within the roll. The induction heating workcoil is unbalanced and is oriented so that minimal currents flow in a direction substantially parallel to the axis of the roll. The induction heating workcoil could include one or more substantially U-shaped or C-shaped cores and at least one coil each wound around at least one of the one or more cores. Also, the roll may further include a shaft and bearings, and the induction heating workcoil can be positioned so that the currents do not flow substantially through the bearings.

Abstract: A combustion system including a plurality of axially staged tubular premixers to control emissions and minimize combustion noise. The combustion system includes a radial inflow premixer that delivers the combustion mixture across a contoured dome into the combustion chamber. The axially staged premixers having a twist mixing apparatus to rotate the fluid flow and cause improved mixing without causing flow recirculation that could lead to pre-ignition or flashback.

Abstract: A combustion system including a plurality of axially staged tubular premixers to control emissions and minimize combustion noise. The combustion system includes a radial inflow premixer that delivers the combustion mixture across a contoured dome into the combustion chamber. The axially staged premixers having a twist mixing apparatus to rotate the fluid flow and cause improved mixing without causing flow recirculation that could lead to pre-ignition or flashback.