Patents by Inventor Keith Mikule

Keith Mikule has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20210115006
    Abstract: The present invention relates to the composition and method of use of Stat3 pathway inhibitors or cancer stem cell inhibitors in combination treatment of cancer.
    Type: Application
    Filed: October 9, 2020
    Publication date: April 22, 2021
    Applicant: Sumitomo Dainippon Pharma Oncology, Inc.
    Inventors: Chiang Jia Li, Keith Mikule, Youzhi Li
  • Patent number: 10377731
    Abstract: The present invention relates to the composition and methods of use of Stat3 pathway inhibitors or cancer stem cell inhibitors in combination treatment of cancer.
    Type: Grant
    Filed: January 14, 2019
    Date of Patent: August 13, 2019
    Assignee: Boston Biomedical, Inc.
    Inventors: Chiang Jia Li, Keith Mikule, Youzhi Li
  • Publication number: 20190135773
    Abstract: The present invention relates to the composition and methods of use of Stat3 pathway inhibitors or cancer stem cell inhibitors in combination treatment of cancer.
    Type: Application
    Filed: January 14, 2019
    Publication date: May 9, 2019
    Inventors: Chiang Jia Li, Keith Mikule, Youzhi Li
  • Publication number: 20180030021
    Abstract: The present invention relates to the composition and methods of use of Stat3 pathway inhibitors or cancer stem cell inhibitors in combination treatment of cancer.
    Type: Application
    Filed: July 11, 2017
    Publication date: February 1, 2018
    Applicant: Boston Biomedical, Inc.
    Inventors: Chiang Jia Li, Keith Mikule, Youzhi Li
  • Patent number: 9732055
    Abstract: The present invention relates to the composition and methods of use of Stat3 pathway inhibitors or cancer stem cell inhibitors in combination treatment of cancer.
    Type: Grant
    Filed: September 10, 2008
    Date of Patent: August 15, 2017
    Assignee: Boston Biomedical, Inc.
    Inventors: Chiang Jia Li, Keith Mikule, Youzhi Li
  • Publication number: 20100310503
    Abstract: The present invention relates to the composition and methods of use of Stat3 pathway inhibitors or cancer stem cell inhibitors in combination treatment of cancer.
    Type: Application
    Filed: September 10, 2008
    Publication date: December 9, 2010
    Inventors: Chiang Jia Li, Keith Mikule, Youzhi Li
  • Publication number: 20050208058
    Abstract: New methods are provided to treat cell proliferative, or other, disorders, or symptoms thereof, by modulating (e.g., inhibiting) centrosomal genes or polypeptides. These methods can include gene silencing (e.g., siRNA), antibodies, aptamers, ribozymes, antisense nucleic acids, and small molecules.
    Type: Application
    Filed: November 22, 2004
    Publication date: September 22, 2005
    Inventors: Stephen Doxsey, Keith Mikule
  • Patent number: 6566047
    Abstract: The present invention provides methods of identifying and using compounds that modulate cell motility. Such compounds can be used to inhibit cancer cell metastasis or promote neurite growth and regenaration. The methods generally relate to the repellent-receptor signalling pathway that controls cellular attachment and detachment to a substratum.
    Type: Grant
    Filed: April 18, 2000
    Date of Patent: May 20, 2003
    Assignee: The Regents of the University of Colorado
    Inventors: Karl Pfenninger, Becky De La Houssaye, Keith Mikule, Steve Helmke, Harry Drabkin