Abstract: Embodiments disclosed herein relate to devices and methods for monitoring one or more physiological parameters of a subject. In an embodiment, a wearable device comprises a substrate configured to be attached to a subject's skin. The substrate comprises a middle portion arranged between two end portions. The wearable device also comprises a physiological sensor. The physiological sensor is configured to sense a physiological signal of the subject when the wearable device is attached to the subject's skin. And, the wearable device comprises one or more electrical components arranged on at least one of the end portions, wherein at least one of the one or more electrical components is coupled to the physiological sensor.

Abstract: An implantable medical device comprises a hermetically sealed housing including at least a first window configured for wireless transfer of an external power signal therethrough, an antenna disposed within the housing at a position such that the antenna can receive the external power signal through the window, and circuitry disposed within the housing and operatively coupled to the antenna.

Abstract: A medical system includes a physiological monitoring system configured to sense a physiological signal and record physiological signal data indicative of the patient's physiological state. The physiological monitoring system including a controller, a storage device, at least one sensor operatively coupled to the controller, and a first communication component. The system includes a mobile device configured to facilitate sensor placement, the mobile device comprising a controller, a display device, and a second communication component configured to facilitate communication between the physiological monitoring system and the mobile device. The controller of the mobile device is configured to provide a graphical user interface (GUI) on the display device, the GUI including information about a proper placement of the at least one sensor, wherein the proper placement is determined based on the physiological signal data.

Abstract: Embodiments herein relate to medical devices and methods for using the same to treat cancerous tumors within a bodily tissue. A medical device system is included having at least one electric field generating circuit configured to generate one or more electric fields; control circuitry in communication with the electric field generating circuit, the control circuitry configured to control delivery of the one or more electric fields from the at least one electric field generating circuit; and two or more electrodes to deliver the electric fields to the site of a cancerous tumor within a patient. At least one electrode can be configured to be implanted. At least one electrode can be configured to be external. The control circuitry can cause the electric field generating circuit to generate one or more electric fields at frequencies selected from a range of between 10 kHz to 1 MHz.

Abstract: Embodiments herein relate to devices and methods for deep tissue optical sensing. In an embodiment, an optical monitoring device is included having a first optical emitter, where the first optical emitter is configured to emit light at a first wavelength. The optical monitoring device includes a first optical detector, where the first optical detector is configured to selectively detect incident light with respect to its angle of incidence on the optical monitoring device. The first optical emitter is configured so that the emitted light from the optical emitter propagates through a tissue at a depth of at least 1 cm into the tissue as measured from a surface of the optical monitoring device. The optical monitoring device is configured to determine a physiological parameter of the tissue using incident light detected by the first optical detector. Other embodiments are also included herein.

Abstract: Embodiments of the present disclosure relate to monitoring one or more physiological parameters of a subject using a multilayer wearable device. In an embodiment, a multilayer wearable device is configured to be attached to a subject. The multilayer wearable device comprises a substrate having multiple layers including a first portion connected to a second portion. The first portion has a first side and a second, opposite side. And the second portion has a first side and a second, opposite side. The first side of the first portion is configured to be attached to the subject and the second portion is arranged on top of the first portion such that the first side of the second portion is disposed adjacent the second side of the first portion. And, the wearable device includes one or more electrical components configured to sense a physiological parameter of the subject.

Abstract: Implantable medical devices (IMD), such as but not limited to leadless cardiac pacemakers (LCP), subcutaneous implantable cardioverter defibrillators (SICD), transvenous implantable cardioverter defibrillators, neuro-stimulators (NS), implantable monitors (IM), may be configured to communicate with each other. In some cases, a first IMD may transmit instructions to a second IMD. In order to improve the chances of a successfully received transmission, the first IMD may transmit the instructions several times during a particular time frame, such as during a single heartbeat. If the second IMD receives the message more than once, the second IMD recognizes that the messages were redundant and acts accordingly.

Abstract: Embodiments disclosed herein relate to devices and methods for monitoring one or more physiological parameters of a subject. In an embodiment, a wearable device comprises a substrate configured to attached to a subject's skin. The substrate comprises a middle portion arranged between two end portions, wherein the middle portion is more flexible than at least one of the end portions. The wearable device also comprises a physiological sensor arranged on the middle portion. The physiological sensor is configured to sense a physiological signal of the subject when the wearable device is attached to the subject's skin. And, the wearable device comprises one or more electrical components arranged on at least one of the end portions, wherein at least one of the one or more electrical components is coupled to the physiological sensor.

Abstract: Embodiments herein relate to devices and methods for measuring cardiogenic airway modulations using optical sensing. In an embodiment, an optical cardiogenic modulation monitoring device can be included having an optical emitter configured to emit light at a first wavelength and an optical detector configured to detect incident light. The monitoring device can be configured so that light emitted from the optical emitter propagates through lung tissue. The monitoring device can also be configured to use detected incident light to measure cardiogenic oscillations of the lung tissue. Other embodiments are also included herein.

Abstract: Embodiments herein relate to devices and methods for assessing deep tissue temperature using optical sensing. In an embodiment an optical temperature monitoring device is included having an optical emitter, wherein the optical emitter is configured to emit light at a first wavelength from 100 nm to 2000 nm. The optical temperature monitoring device also includes an optical detector configured to detect incident light. The optical temperature monitoring device can be configured so that the light from the optical emitter propagates at a depth of at least 1 cm through tissue as measured from a surface of the optical temperature monitoring device and back to the optical detector and the incident light detected by the optical detector is used to determine a temperature of the tissue at depths of at least 1 cm as measured from a surface of the optical temperature monitoring device. Other embodiments are also included herein.

Abstract: Embodiments herein relate to devices and methods for assessing pulmonary congestion using optical sensing techniques. In an embodiment, a pulmonary congestion monitoring device can be included having a first optical emitter, wherein the first optical emitter can be configured to emit light at a first wavelength, such as at a near-infrared wavelength or an ultraviolet wavelength. The monitoring device can also include a first optical detector configured to detect incident light. The first optical emitter and the first optical detector can be separated by a distance of 1 centimeters (cm) to 10 cm. The monitoring device can be configured so that the light from the first optical emitter propagates through at least one of a lung tissue and an airway tissue. The monitoring device can also be configured to use detected incident light to determine a congestion status of the lung tissue. Other embodiments are also included herein.

Abstract: Embodiments herein relate to devices and methods for assessing pulmonary status using optical oxygenation sensing. In an embodiment, an oxygenation monitoring device can be included having a first optical emitter, wherein the first optical emitter can be configured to emit light at a first wavelength from 100 nanometers (nm) to 2000 nm. The oxygenation monitoring device and further include a first optical detector, wherein the first optical detector can be configured to detect incident light. The device can be configured so that emitted light from the first optical emitter propagates through a lung tissue and detected incident light can be used to determine an oxygenation status of the lung tissue. Other embodiments are also included herein.

Abstract: Embodiments of the present disclosure relate to heart sound measurements using mobile devices. In an embodiment, a medical system for monitoring heart sounds of a subject comprises a medical device configured to obtain, during a first sampling interval, a first physiological signal. The medical system further comprises a mobile device comprising an accelerator, wherein the accelerator is configured to obtain, during a second sampling interval, a second physiological signal. And, the medical system comprises an analysis component configured to extract heart sounds data from the second physiological signal.

Abstract: A bridge device includes a housing, a plurality of electrodes exposed outside of the housing such that at least two of the plurality of electrodes can be concurrently placed in contact with a patient's skin. A controller is disposed within the housing. A first communications module is operably coupled to the controller and to the at least two of the plurality of electrodes. The first communications module is configured to allow the controller to communicate with an implantable medical device via at least two of the plurality of electrodes using conducted communication. A second communications module is operably coupled to the controller and is configured to allow the controller to communicate with a remote device external to the patient.

Abstract: A battery includes a battery case including a housing having side walls defining a first open end and a second open end, the battery case including a separate top cover to cover the first open end of the housing and a separate bottom cover to cover the second open end of the housing; a first electrode located within the case; a second electrode located within the case; a first terminal coupled to the first electrode and exposed outside the case; and a second terminal coupled to the second electrode and exposed outside the case.

Abstract: Systems, methods and implantable devices configured to provide cardiac resynchronization therapy and/or bradycardia pacing therapy. A first device located in the heart of the patient is configured to receive a communication from a second device and deliver a pacing therapy in response to or in accordance with the received communication. A second device located elsewhere is configured to determine an atrial event has occurred and communicate to the first device to trigger the pacing therapy. The second device may be configured for sensing the atrial event by the use of vector selection and atrial event windowing, among other enhancements. Exception cases are discussed and handled as well.

Abstract: Systems and methods for managing communication strategies between implanted medical devices. Methods include temporal optimization relative to one or more identified conditions in the body. A selected characteristic, such as a signal representative or linked to a biological function, is assessed to determine its likely impact on communication capabilities, and one or more communication strategies may be developed to optimize intra-body communication.

Abstract: Methods, systems and devices for providing cardiac resynchronization therapy (CRT) to a patient using a leadless cardiac pacemaker (LCP) and an extracardiac device (ED). The LCP is configured to deliver pacing therapy at a pacing interval. Illustratively, the ED may be configured to analyze the cardiac cycle including a portion preceding the pacing therapy delivery for one or several cardiac cycles, and determine whether an interval from the P-wave to the pace therapy in the cardiac cycle(s) is in a desired range. In an example, if the P-wave to pace interval is outside the desired range, the ED communicates to the LCP to adjust the pacing interval.

Abstract: An implantable fluid operated device may include a fluid reservoir configured to hold fluid, an inflatable member, and a pump assembly configured to transfer fluid between the fluid reservoir and the inflatable member. The pump assembly may include one or more fluid pumps and one or more valves. One or more sensing devices may be positioned within fluid passageways of the fluid operated device. The electronic control system may control operation of the pump assembly based on fluid pressure measurements and/or fluid flow measurements received from the one or more sensing devices. The pump assembly may include a piezoelectric pump. The one or more sensing devices may include one or more pressure transducers positioned in the fluid passageways, one or more strain gauges measuring deflection of piezoelectric elements, voltage input/output at one or more piezoelectric elements, and other types of sensing devices.

Abstract: An implantable leadless cardiac pacing device and associated delivery and retrieval devices. The implantable device includes a docking member extending from the proximal end of the housing of the implantable device configured to engage with the delivery and/or retrieval device to facilitate delivery and/or retrieval of the implantable leadless cardiac pacing device.