Patents by Inventor Kelley W. Moremen

Kelley W. Moremen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Vivo isotopic labeling method for quantitative glycomics
    Patent number: 9329169
    Abstract: The present invention relates to a method of isotopically labeling glycans and in facilitating high throughput quantitative/comparative analysis of glycomic compositions of biological cells. The method is applicable inter alia for identifying differentiated cells and their glycomic characteristics, differentiation conditions, disease and/or therapeutic progression, diagnosing disease states, determining drug activity, establishing manufacturing efficiencies and for determining the half-life of glycans in cells.
    Type: Grant
    Filed: October 29, 2008
    Date of Patent: May 3, 2016
    Assignee: UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC
    Inventors: Robert Lance Wells, Ronald C. Orlando, Stephen Dalton, Kelley W. Moremen, James Michael Pierce, James A. Atwood, III, Michael Tiemeyer, William S. York
  • Lectins and coding sequences
    Patent number: 6524820
    Abstract: The present disclosure provides a novel family of C-type lectins from vertebrates. As specifically exemplified, this family of lectins includes a melibiose-specific lectin (XL35) from Xenopus laevis oocytes, and two human lectins, HL-3 and HL-13, specifically expressed in endothelial cells such as blood vessels, stomach, small intestine, heart and tissue and in small intestine, respectively. Amino acid sequences of the lectin proteins are provided herein, together with the nucleotide sequences encoding these proteins.
    Type: Grant
    Filed: November 9, 2000
    Date of Patent: February 25, 2003
    Assignee: University of Georgia Research Foundation, Inc.
    Inventors: J. Michael Pierce, Kelley W. Moremen, Jin Kyu Lee
  • Transgenic non-human mammals expressing heterologous glycosyltransferase DNA sequences produce oligosaccharides and glycoproteins in their milk
    Patent number: 6204431
    Abstract: The subject invention relates to methods of producing non-human transgenic mammals which produce various oligosaccharides and glycoconjugates in their milk. Additionally, the subject invention relates to the mammals themselves, the milk which they produce, compositions comprising the milk, fractions of the milk, and the purified oligosaccharides, as well as glyconjugates, present in the milk.
    Type: Grant
    Filed: September 5, 1997
    Date of Patent: March 20, 2001
    Assignee: Abbott Laboratories
    Inventors: Pedro A. Prieto, John J. Kopchick, Richard D. Cummings, James M. Pierce, David F. Smith, Kelley W. Moremen
  • Lectins and coding sequences
    Patent number: 6146849
    Abstract: The present disclosure provides a novel family of C-type lectins from vertebrates. As specifically exemplified, this family of lectins includes a melibiose-specific lectin (XL35) from Xenopus laevis oocytes, and two human lectins, HL-3 and HL-13, specifically expressed in endothelial cells such as blood vessels, stomach, small intestine, heart and tissue and in small intestine, respectively. Amino acid sequences of the lectin proteins are provided herein, together with the nucleotide sequences encoding these proteins.
    Type: Grant
    Filed: June 4, 1998
    Date of Patent: November 14, 2000
    Assignee: University of Georgia Research Foundation Inc.
    Inventors: J. Michael Pierce, Kelley W. Moremen, Jin Kyu Lee