Patents by Inventor Kelli L. Kuhen
Kelli L. Kuhen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 9963454Abstract: The invention provides a class of compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent malaria.Type: GrantFiled: December 22, 2015Date of Patent: May 8, 2018Assignee: Novartis AGInventors: Arnab K. Chatterjee, Kelli L. Kuhen, Advait S. Nagle, David C. Tully, Tao Wu
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Patent number: 9469645Abstract: The invention provides a class of compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent malaria.Type: GrantFiled: June 7, 2013Date of Patent: October 18, 2016Assignee: Novartis AGInventors: Arnab K. Chatterjee, Advait S. Nagle, Tao Wu, David C. Tully, Kelli L. Kuhen
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Publication number: 20160108051Abstract: The invention provides a class of compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent malaria.Type: ApplicationFiled: December 22, 2015Publication date: April 21, 2016Applicant: NOVARTIS AGInventors: Arnab K. Chatterjee, Kelli L. Kuhen, Advait S. Nagle, David C. Tully, Tao Wu
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Publication number: 20130281403Abstract: The invention provides a class of compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent malaria.Type: ApplicationFiled: June 7, 2013Publication date: October 24, 2013Inventors: Arnab K. Chatterjee, Advait S. Nagle, Tao Wu, David C. Tully, Kelli L. Kuhen
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Patent number: 8557801Abstract: The invention provides a class of compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent malaria.Type: GrantFiled: July 9, 2010Date of Patent: October 15, 2013Assignee: IRM LLCInventors: Arnab K. Chatterjee, Advait S. Nagle, Tao Wu, David C. Tully, Kelli L. Kuhen
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Publication number: 20110059934Abstract: The invention provides a class of compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent malaria.Type: ApplicationFiled: July 9, 2010Publication date: March 10, 2011Applicant: IRM LLCInventors: Arnab K. Chatterjee, Advait S. Nagle, Tao Wu, David C. Tully, Kelli L. Kuhen
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Patent number: 7604977Abstract: This invention provides novel methods for identifying agents that inhibit HIV infection. The anti-HIV agents are identified by screening test compounds for ability to modulate a biological activity of isopeptidase T (IsoT), e.g., its isopeptidase activity or its binding to another molecule such as viral protein R (Vpr). Such IsoT modulators can be further examined for their activity in inhibiting an activity indicative of HIV infection or HIV replication. These novel anti-HIV agents are useful in the prevention or treatment of HIV infection and conditions associated with or caused by HIV infection.Type: GrantFiled: April 21, 2006Date of Patent: October 20, 2009Assignee: IRM LLCInventors: Kelli L. Kuhen, Jeremy S. Caldwell
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Patent number: 7601742Abstract: The present invention relates to inhibition of viruses, e.g., HIV using pyrrolidones and compounds related to pyrrolidones. The invention further relates to methods for identifying and using agents, including small molecule chemical compositions that inhibit HIV in a cell; as well as to methods of prophylaxis, and therapy related to HIV infection and related disease states such as AIDS.Type: GrantFiled: April 22, 2008Date of Patent: October 13, 2009Assignee: IRM LLCInventors: Baogen Wu, Yun He, Truc Ngoc Nguyen, Kelli L. Kuhen, David Archer Ellis, Tao Jiang, Xiaohui He, Kunyong Yang, Badry Bursulaya
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Publication number: 20090252757Abstract: This invention provides novel HIV-interacting host factors. The invention also provides methods of using the HIV-interacting host factors to screen for compounds that inhibit HIV infection. The methods comprise first screening test compounds for modulators of an HIV interacting host factor disclosed herein, and then further screening the identified modulating compounds for ability to inhibit HIV infection. The invention further provides methods and pharmaceutical compositions for treating diseases and conditions associated with HIV infection.Type: ApplicationFiled: December 8, 2006Publication date: October 8, 2009Applicant: IRM LLCInventors: Deborah Nguyen, Kelli L. Kuhen, Jeremy S. Caldwell
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Patent number: 7495016Abstract: The present invention relates to inhibition of viruses, e.g., HIV using pyrrolidones and compounds related to pyrrolidones. The invention further relates to methods for identifying and using agents, including small molecule chemical compositions that inhibit HIV in a cell; as well as to methods of prophylaxis, and therapy related to HIV infection and related disease states such as AIDS.Type: GrantFiled: October 21, 2003Date of Patent: February 24, 2009Assignee: IRM LLCInventors: Baogen Wu, Yun He, Truc Ngoc Nguyen, Kelli L. Kuhen, David Archer Ellis, Tao Jiang, Xiaohui He, Kunyong Yang, Badry Bursulaya
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Publication number: 20080255136Abstract: The present invention relates to inhibition of viruses, e.g., HIV using pyrrolidones and compounds related to pyrrolidones. The invention further relates to methods for identifying and using agents, including small molecule chemical compositions that inhibit HIV in a cell; as well as to methods of prophylaxis, and therapy related to HIV infection and related disease states such as AIDS.Type: ApplicationFiled: April 22, 2008Publication date: October 16, 2008Applicant: IRM LLCInventors: Baogen Wu, Yun He, Truc Nguyen, Kelli L. Kuhen, David Archer Ellis, Tao Jiang, Xiaohui He, Kunyong Yang, Badry Bursulaya
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Patent number: 7205328Abstract: The present invention relates to inhibition of viruses, e.g., HIV using oxindoles and compounds related to oxindoles. The invention further relates to methods for identifying and using agents, including small molecule chemical compositions that inhibit HIV in a cell; as well as to methods of prophylaxis, and therapy related to HIV infection and related disease states such as AIDS.Type: GrantFiled: October 21, 2003Date of Patent: April 17, 2007Assignee: IRM LLCInventors: Yun He, Tao Jiang, Kelli L. Kuhen, David Archer Ellis, Baogen Wu, Tom Yao-Hsiang Wu, Badry Bursulaya
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Patent number: 7019141Abstract: The present invention relates to inhibition of viruses, e.g., HIV using quinolones and compounds related to quinolones. The invention further relates to methods for identifying and using agents, including small molecule chemical compositions that inhibit HIV in a cell; as well as to methods of prophylaxis, and therapy related to HIV infection and related disease states such as AIDS.Type: GrantFiled: October 21, 2003Date of Patent: March 28, 2006Assignee: IRM LLCInventors: Yun He, David Archer Ellis, Beth Marie Anaclerio, Kelli L. Kuhen, Baogen Wu, Tao Jiang
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Publication number: 20040157859Abstract: The present invention relates to inhibition of viruses, e.g., HIV using pyrrolidones and compounds related to pyrrolidones. The invention further relates to methods for identifying and using agents, including small molecule chemical compositions that inhibit HIV in a cell; as well as to methods of prophylaxis, and therapy related to HIV infection and related disease states such as AIDS.Type: ApplicationFiled: October 21, 2003Publication date: August 12, 2004Applicant: IRM LLC, a Delaware LLCInventors: Baogen Wu, Yun He, Truc Ngyuen, Kelli L. Kuhen, David Archer Ellis, Tao Jiang, Xiaohui Xe, Kunyong Yang, Badry Bursulaya
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Publication number: 20040152755Abstract: The present invention relates to inhibition of viruses, e.g., HIV using oxindoles and compounds related to oxindoles. The invention further relates to methods for identifying and using agents, including small molecule chemical compositions that inhibit HIV in a cell; as well as to methods of prophylaxis, and therapy related to HIV infection and related disease states such as AIDS.Type: ApplicationFiled: October 21, 2003Publication date: August 5, 2004Applicant: IRM LLC, a Delaware LLCInventors: Yun He, Tao Jiang, Kelli L. Kuhen, David Archer Ellis, Baogen Wu, Tom Yao-Hsiang Wu, Badry Bursulaya
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Publication number: 20040152719Abstract: The present invention relates to inhibition of viruses, e.g., HIV using quinolones and compounds related to quinolones. The invention further relates to methods for identifying and using agents, including small molecule chemical compositions that inhibit HIV in a cell; as well as to methods of prophylaxis, and therapy related to HIV infection and related disease states such as AIDS.Type: ApplicationFiled: October 21, 2003Publication date: August 5, 2004Applicant: IRM LLC, a Delaware LLCInventors: Yun He, David Archer Ellis, Beth Marie Anaclerio, Kelli L. Kuhen, Baogen Wu, Tao Jiang