Abstract: The present invention relates to method for assaying anti-cyclic citrullinated peptide antibodies in a clinical sample, said method comprising contacting said sample with at least one homogeneous reagent comprising at least one specific binder for anti-CCP antibodies, whereby to form a solution or suspension of an anti-CCP-binding partner complex in a homogeneous sample mixture and detecting the presence or level of said anti-CCP-binding partner complex in a homogeneous liquid-phase. The invention also relates to a method for the assessment of the existence of; risk of; potential for; or propensity to RA in a subject.

Abstract: Compositions and assay methods for and relating to the detection of glycated hemoglobin are provided. In particular, the presence and level of glycated hemoglobin can be detected in a blood sample. The compositions comprise microparticles which have zinc coating for use in the improved binding of proteins exhibiting a zinc binding domain, in particular glycated hemoglobin.

Abstract: Compositions and assay methods for and relating to the detection of glycated hemoglobin are provided. In particular, the presence and level of glycated hemoglobin can be detected in a blood sample. The compositions comprise microparticles which have zinc coating for use in the improved binding of proteins exhibiting a zinc binding domain, in particular glycated hemoglobin.

Abstract: A system and method is provided for generating menu/toolbar entities on a graphical user interface. An application is provided which can be displayed in a frame of a graphical user interface and which has a set of menu/toolbar entities. At any given time, the application can be in one of a plurality of application states. Information indicative of an application state characteristic for each application state of the application is contained in a data file, and each application state characteristic defines a display characteristic of at least one of the set of menu/toolbar entities. The system generates a displayed set of menu/toolbar entities on the graphical user interface based upon the application state characteristic of a current one of the application states of the application.

Abstract: A system and method is provided for generating menu/toolbar entities on a graphical user interface having a parent frame for displaying menu/toolbar entities and a plurality of child frames. A set of applications is provided which can be displayed in the plurality of child frames. Each application has a corresponding set of menu/toolbar entities and information indicative of a policy for each menu/toolbar entity of each application is contained in a data file. Preferably, each application has a corresponding data file. A displayed set of menu/toolbar entities on the graphical user interface is generated based upon the policies of the menu/toolbar entities for a currently focused one of the applications.