Abstract: It is intended to provide a kit or a device for the detection of breast cancer and a method for detecting breast cancer. The present invention provides a kit or a device for the detection of breast cancer, comprising nucleic acid(s) capable of specifically binding to a miRNA in a sample of a subject, and a method for detecting breast cancer, comprising measuring the miRNA in vitro.

Abstract: A production method includes a forging step, a flash-trimming step, and a pressing step. In the forging step, a finish-forged product with flash is formed by an upper forging, die and a lower forging die. In the forging step, an excess portion is formed on at least one crankarm which is connected to a first or third pin, in a portion near the first or third pin, on an outer periphery of a lateral part near the upper forging die, such that the excess portion protrudes from the outer periphery. In the pressing step, the excess portion is pressed by an upper die such that the excess portion bulges toward a journal. This method allows production of a forged crankshaft with a reduced weight and a sufficient rigidity in a simple facility.

Abstract: The production method disclosed is a method for producing a front axle beam. The production method includes a die forging step and a bending step. The die forging step is a step of forging a steel material with dies to produce a forged product including a rough web part, which is to be formed into a web part, and four plate-shaped rough flange parts protruding frontward and rearward from an upper side and a lower side of the rough web part, respectively. The bending step is a step of pressing at least one specified rough flange part, which is at least one of the four rough flange parts, with a first die to form a bent portion in the specified rough flange part such that the bent portion is bent inward in an up-down direction of the forged product.

Abstract: The production method includes a first step, a second step and a third step. In the first step, a steel material is forged by dies, whereby a forged product including a rough web part and four plate-shaped rough flange parts is produced. In the second step, at least one specified rough flange part, which is at least one of the four rough flange parts, is pressed by a first die, whereby a first bent portion bending outward in an up-down direction is formed in the specified rough flange part. In the third step, the edge of the first bent portion is pressed by a second die inward in the up-down direction, whereby the edge is deformed and a second bent portion is formed. In the third step, the edge of the specified flange part is deformed while the edge is kept from deforming in a front-rear direction.

Abstract: In a pressing step, a first forged product is pressed by a first die, and thereby, a second forged product including a rough flange having a thickness-changing portion is produced. The thickness-changing portion includes a front part protruding frontward from a side of a rough web part and a rear part protruding rearward from the side of the rough web part. Each of the front part and the rear part includes a first part, and a second part that is thicker than the first part and is located farther from the rough web part than the first part. In the pressing step, at least a part of the rough flange that is above or below the web part (thick part) is pressed by the first die, whereby the material of the first forged product in the part is caused to flow frontward and rearward, and the thickness-changing portion is formed.

Abstract: A disclosed front axle beam includes a beam section. The beam section includes a first flange part, a second flange part, and a web section connecting the first flange part and the second flange part. The web section includes a varying-slope section that includes a plurality of first slope sections and a plurality of second slope sections. Each of the plurality of first slope sections inclines in one direction with respect to the vehicle-height direction in a cross section perpendicular to the longitudinal direction. Each of the plurality of second slope sections inclines in the opposite direction to the one direction with respect to the vehicle-height direction in a cross section perpendicular to the longitudinal direction. The first slope section and the second slope section are located in an alternate manner along the longitudinal direction. In this way, the rigidity of the front axle beam can be increased.

Abstract: A method for producing a forged crankshaft includes a die forging step of forming a forged blank having a crankshaft shape by die forging, and a pressing step of pressing the forged blank by a first dies. The forged blank includes first excess portions attached to some or all of crank arms each incorporating a counterweight, each of the first excess portions protrudes from a side portion of the crank arm, in a region near a journal. In the pressing step, the first excess portions are deformed by the first dies such that each of the first excess portions bulges toward a pin. This facilitates the production of a forged crankshaft with a reduced weight and assured stiffness.

Abstract: A forged crankshaft production method includes a first preforming step, a second preforming step, and a final preforming step. The first pair of dies includes web processing parts to come into contact with portions to be formed into arms and portions to be formed into weights integrated with the arms. Each of the web processing parts includes an arm processing part and a weight processing part. The arm processing part and the weight processing part form a recessed portion, and the width of the open side of the weight processing part becomes greater with increasing distance from the bottom of the recessed portion. Accordingly, in the blank, volume can be distributed between a portion to be formed into an arm and a portion to be formed into a weight integrated with the arm, and the material yield rate can be improved.

Abstract: The disclosed production method includes a die forging step of obtaining a forged blank with flash having a crankshaft shape, and a trimming step of removing the flash from the forged blank while nipping the forged blank with a pair of holding dies. In the forged blank, at least one of the rough crank arms have, in a region near an adjacent rough pin, a first excess portion protruding from an outer periphery of a side portion of the rough crank arm. When the forged blank is nipped with the pair of holding dies, the first excess portion is deformed by the pair of holding dies to bulge toward an adjacent rough journal.

Abstract: The disclosed production method includes a rough forging step of performing die forging to obtain a rough forged blank with flash having a crankshaft shape, and a finish forging step of applying die forging by use of a first pair of dies to the rough forged blank to obtain a finish forged blank with flash. In the rough forged blank, at least one of the rough crank arms have, in a region near an adjacent rough pin, a first excess portion protruding from an outer periphery of a side portion of the rough crank arm. During the die forging in the finish forging step, the first excess portion is deformed by the first pair of dies to bulge toward an adjacent rough journal.

Abstract: The invention has for its object to use an evaporation-spray drying process thereby providing layered silicate powder granules, each one containing a flat particle having an opening or recess in its surface center. Each of the layered silicate powder granule contains a flat particle including a layered silicate formed by evaporation-spray drying and a rheology modifier for modifying the crystal edge face of the layered silicate and having an opening or recess in its surface center.

Abstract: A forged crankshaft production method includes a first preforming step, a second preforming step, and a final preforming step. In the first preforming step, sectional areas of portions to be formed into pins and sectional areas of portions to be formed into journals are decreased, whereby flat portions are formed, and the portion to be formed into the pin located at a second position is decentered. In the second preforming step, a portion to be formed into the pin located at a first position is decentered, and a portion to be formed into the pin located at a third position is decentered to a side opposite to the portion to be formed into the pin located at the first position. In a blank obtained thereby, portions to be formed into pins have been reduced and decentered, and the material yield rate can be improved.

Abstract: A DC power supply unit is provided that allows for improving efficiency and reducing harmonic currents. A DC power supply unit includes: a bridge rectification circuit having diodes and MOSFETs; a reactor that is arranged between the AC power supply and the bridge rectifier circuit; a smoothing capacitor that is connected to an output side of the bridge rectifier circuit and smoothes a voltage; and a converter control unit that executes, based on predetermined threshold values, a diode rectification control that uses diodes and parasitic diodes of the MOSFETs, a synchronous rectification control that switches the MOSFETs in synchronization with a polarity of the voltage of the AC power supply, a partial switching control that repeats partially short-circuiting the reactor multiple times in a half cycle of the AC power supply, or a fast switching control that short-circuits the reactor at a predetermined frequency over a full AC cycle.

Abstract: Disclosed are rare earth phosphate particles that include aggregated particles formed of a plurality of primary particles of a rare earth phosphate represented by LnPO4, wherein Ln represents at least one element selected from the group consisting of Sc, Y, La, Ce, Pr, Nd, Sm, Eu, Gd, Tb, Dy, Ho, Er, Yb, and Lu. The cumulative volume particle size at a cumulative volume of 50 vol %, D50, of the aggregated particles is from 0.1 ?m to 20 ?m as measured through particle size distribution analysis using a laser diffraction and scattering method. The rare earth phosphate particles are to be distributed in a substrate or on a surface of a substrate and used to cause scattering of light.

Abstract: Provided is a production method, including a first preforming process, a second preforming process, a final preforming process, and a finish forging process. In the first preforming process, regions to be a pin and a journal are pressed respectively from a direction perpendicular to an axial direction of the billet, thus reducing cross sectional areas of each region and forming a plurality of flat parts. In the second preforming process, the first preform is pressed in the pressing direction, which is a direction perpendicular to decentering direction of a region to be a second pin. In the final preforming process, the second preform is pressed from a direction perpendicular to an axial direction of the second preform, and further a region to be a counterweight and a region to be a crank arm integrally including a counterweight are pressed in the axial direction of the second preform.

Abstract: Provided is a production method, including a first preforming process, a second preforming process, a final preforming process, and a finish forging process. In the first preforming process, regions to be a pin and a journal are pressed respectively from a direction perpendicular to an axial direction of the billet, thus reducing cross sectional areas of each region and forming a plurality of flat parts. In the second preforming process, the first preform is pressed in the pressing direction, which is a width direction of the flat parts. In the final preforming process, the second preform is pressed from a direction perpendicular to an axial direction of the second preform, and further a region to be a counterweight and a region to be a crank arm integrally including a counterweight are pressed in the axial direction of the second preform.

Abstract: A method for producing a forged crankshaft includes: a preforming step of forming a preformed blank with no flash, the preformed blank including a shape of the crankshaft, wherein the crank arm have excess projecting portions at an outer peripheries of side portions of the crank arm near the crank pin; a die forging step of forming a forged blank with flash by pressing the preformed blank with a pair of first dies; and a trimming step of removing the flash from the forged blank. In the die forging step, while a second die is abutted against a journal-side surface of the crank arm and holds the surface, the excess projecting portions of the crank arm are deformed by the first dies so as to increase the side portions of the crank arm in thickness.

Abstract: A boosting operation of a converter and the intermittent energization operation of an inverter are optimally performed in accordant with input or output. The power converter includes the converter capable of boosting a DC voltage outputted by switching operation alternately performing shorting and rectification; the inverter; an inverter capable of performing intermittent energization in which switching around zero cross of a motor current is turned off upon converting the DC voltage outputted by the converter into three-phase AC power; and a controller that controls the converter to perform boosting operation and the inverter to perform the boosting operation of the converter and the intermittent energization operation of the inverter linkingly.

Abstract: A crankshaft includes journals serving as a central axis of rotation, crank pins decentered from the journals, and crank arms connecting the journals and the crank pins. Some or all of the crank arms have counterweights integrated therewith. At least one of the crank arms has a recess in a crank pin facing surface. The crank arm includes ribs formed respectively in two side portions of the recess along a periphery of the crank arm.

Abstract: A sound processing apparatus includes a processor to obtain sound data and image data, wherein the sound data is collected from a sound source in a given area by a sound collection unit including a plurality of microphones and the image data is captured by an imaging unit which captures an image at least partially in the given area, to designate a direction defined relative to the sound collection unit, wherein the designated direction corresponds to a designation part on an image displayed based on the image data, to designate an arbitrary range in the given area, wherein the designated arbitrary range corresponds to a designation part on the image displayed based on the image data, and to emphasize a sound component in the sound data in the direction designated by the first designation unit within the arbitrary range designated by the second designation unit.