Abstract: Disclosed herein inter alia are compositions and methods useful in the treatment of infectious diseases and exposure to toxins.

Abstract: A sandwich panel joint assembly for a nacelle of a wind turbine and method of manufacturing same is disclosed. The method includes forming at least one groove into a core structure. A next step includes inserting at least one fastener element within the groove such that the fastener element is recessed within the core structure. The method also includes placing the core structure containing the fastener element into a mold. A next step includes inserting a resin material into the mold to at least partially surround the core structure, wherein a portion of the fastener element becomes embedded within the resin material. The resin material is then allowed to cure so as to form a plurality of panel members that surround the core structure. As such, the fastener element is recessed within the core structure and molded into one of the cured panel members.

Abstract: A nacelle for a wind turbine includes a cover defining an internal volume. The cover extends along a longitudinal direction, and the cover has a predefined length, a predefined width and a predefined height. The cover has multiple sections configured to be fastened together to form the cover. The multiple sections are configured to fasten to one or more longitudinal extension sections. The longitudinal extension sections are configured to fasten to the cover and extend a longitudinal length of the cover to a second length. The second length is greater than the predefined length.

Abstract: Various embodiments of the present invention involve systems, methods, and computer program products utilized in facilitating alternative delivery options for customers. In certain embodiments, a consignee may meet a driver and receive an item at a location different from the delivery address associated with the item. The receipt of the item may be prior to the driver attempting to deliver the item to the designated shipping location or after an unsuccessful delivery attempt. The carrier, the driver, the carrier system, the mobile station, and/or the sensors located on the item may communicate with the consignee to arrange a mutually acceptable time and location to accomplish the delivery. In certain embodiments, the consignee may be responsible for arriving at a dynamic delivery location to retrieve the item while the driver is at the location performing other tasks.

Abstract: Computer program products, methods, systems, apparatus, and computing entities are provided. In one embodiment, a connection between an electronic door hanger and a customer computing entity can be established at a customer's location. With a connection established, information about an attempted (e.g., successful/unsuccessful) pick-up or delivery can be automatically provided to the customer computing entity.

Abstract: Computer program products, methods, systems, apparatus, and computing entities are provided. In one embodiment, a connection between an electronic door hanger and a customer computing entity can be established at a customer's location. With a connection established, information about an attempted (e.g., successful/unsuccessful) pick-up or delivery can be automatically provided to the customer computing entity.

Abstract: In one aspect, a rotor hub assembly for a wind turbine is disclosed. The rotor hub assembly may generally comprise an inner hub including a plurality of hub segments assembled together and a hub enclosure including a plurality of enclosure segments assembled together. The hub enclosure may be configured to at least partially enclose the inner hub. In addition, the rotor hub assembly may include a plurality of support members extending between the inner hub and the hub enclosure.

Abstract: In one aspect, a rotor hub assembly for a wind turbine is disclosed. The rotor hub assembly may generally comprise an inner hub including a plurality of hub segments assembled together and a hub enclosure including a plurality of enclosure segments assembled together. The hub enclosure may be configured to at least partially enclose the inner hub. In addition, the rotor hub assembly may include a plurality of support members extending between the inner hub and the hub enclosure.

Abstract: Methods and apparatus for analyzing surface properties of particles are provided. A method for analyzing the surface properties of the particle includes a associating a first particle with a first capture zone having a specific binding affinity for a first chemical species, applying an optical force to the first particle, sensing a response of the first particle to the optical force, and using the sensed response to determine the presence, absence or quantity of the first chemical species on the first particle surface. This process may be repeated in parallel to test multiple particles. In addition to directly testing the surface properties of the particles, the method can be used in direct, indirect and competitive assays to determine the presence, absence or quantity of free or immobilized analytes. A fluidic cartridge with capture zones having avidities that are tuned for the use of optical forces is provided. A software routine for performing the method is also provided.

Abstract: Applicants' teachings relate to a method and device to extract components contained in a fluid. More particularly, the applicants' teachings are directed towards a method and sampling device for quick extraction of targeted components from their in vivo surroundings. In accordance with various embodiments of applicants' teachings a sampling device and method to extract components, such as, for example, analytes, from a fluid is provided. The device is interfaced with a fluid source, such as, for example, but not limited to, a circulatory system of an animal, to enable extraction of target molecules with minimal loss of fluid (e.g., blood) to the source. The device facilitates an interface between the circulatory system of an animal and a suitable sampling probe such as, for example, a solid phase microextraction (SPME) probe. The targeted compounds are desorbed in small volumes of solvents that can be analyzed with highly specific instruments.

Abstract: A submicron structure having a silica body defining a plurality of pores, said silica body further defining an outer surface between pore openings of said plurality of pores; and having at least one silver nanocrystal within said silica body are described. Antimicrobial compositions comprising the submicron structure, and methods of killing or inhibiting growth of microbes using the submicron structure are described.

Abstract: A nacelle for a wind turbine includes a cover defining an internal volume. The cover has longitudinal sides and opposite end walls. A bedplate is within the cover with the power generation and wind turbine control components mounted on the bedplate. The cover has a widest width dimension along the longitudinal sides intermediate of the end walls that exceeds a pre-defined maximum width for rail transport of the nacelle. Removable caps are configured on the longitudinal sides of the cover at the widest dimension, with the caps having a configuration such that upon removal of the caps, the widest width dimension is less than the predefined maximum width for rail transport.

Abstract: A wet wipe that is formed from a nonwoven structure that comprises a matrix of at least one meltblown fibrous material and at least one secondary fibrous material is disclosed. A weight ratio of the at least one secondary fibrous material to the at least one meltblown fibrous material may be between about 40/60 to about 90/10. Additionally, the nonwoven structure has a first side with a textured surface having a three-dimensional texture that includes a plurality of peaks and valleys and a second side with a substantially planar surface. The nonwoven structure includes about 150 to about 600 wt. % of a liquid solution to prepare a wet wipe. The difference in a cleaning pickup percentage between the first side and the second side of the wet wipe is less than 30%, more desirably less than 20%, and even more desirably less than 15%.

Abstract: A nacelle for a wind turbine includes a cover defining an internal volume. The cover has longitudinal sides and opposite end walls. A bedplate is within the cover with the power generation and wind turbine control components mounted on the bedplate. The cover has a widest width dimension along the longitudinal sides intermediate of the end walls that exceeds a pre-defined maximum width for rail transport of the nacelle. Removable caps are configured on the longitudinal sides of the cover at the widest dimension, with the caps having a configuration such that upon removal of the caps, the widest width dimension is less than the predefined maximum width for rail transport.

Abstract: Methods and apparatus for analyzing surface properties of particles are provided. A method for analyzing the surface properties of the particle includes a associating a first particle with a first capture zone having a specific binding affinity for a first chemical species, applying an optical force to the first particle, sensing a response of the first particle to the optical force, and using the sensed response to determine the presence, absence or quantity of the first chemical species on the first particle surface. This process may be repeated in parallel to test multiple particles. In addition to directly testing the surface properties of the particles, the method can be used in direct, indirect and competitive assays to determine the presence, absence or quantity of free or immobilized analytes. A fluidic cartridge with capture zones having avidities that are tuned for the use of optical forces is provided. A software routine for performing the method is also provided.

Abstract: A method for installing an offshore wind turbine system includes driving a cylindrical annular monopile or a substructure into the soil. The monopile includes a flanged portion configured to support a wind turbine tower or a superstructure. The flanged portion extends radially from a peripheral surface of the monopile. The method further includes mounting a wind turbine tower directly on to the monopile, wherein the wind turbine is supported by the flanged portion of the monopile.

Abstract: The present invention provides compositions useful in preparing and/or serving as antitoxins against Bacillus anthracis, the causative agent of anthrax. The present invention also provides polypeptides and polynucleotides relating to the capillary morphogenisis gene 2 (CMG-2), vectors containing the polynucleotides and polypeptides, and host cells containing related polynucleotide molecules, all used in association with the treatment of, or the research and development of treatments for anthrax. The present invention also relates to methods for identifying molecules that bind CMG-2 and molecules that reduce the toxicity of anthrax toxin. Finally, the present invention provides methods for treating human and non-human animals suffering from anthrax.

Abstract: Applicants' teachings relate to a method and device to extract components contained in a fluid. More particularly, the applicants' teachings are directed towards a method and sampling device for quick extraction of targeted components from their in vivo surroundings. In accordance with various embodiments of applicants' teachings a sampling device and method to extract components, such as, for example, analytes, from a fluid is provided. The device is interfaced with a fluid source, such as, for example, but not limited to, a circulatory system of an animal, to enable extraction of target molecules with minimal loss of fluid (e.g., blood) to the source. The device facilitates an interface between the circulatory system of an animal and a suitable sampling probe such as, for example, a solid phase microextraction (SPME) probe. The targeted compounds are desorbed in small volumes of solvents that can be analyzed with highly specific instruments.

Abstract: A method for manipulating particles (micro, nano, and pico) having one or more characteristics with an optical trap formed by modulating a laser beam with a Diffractive Optical Element (DOE). At least one characteristic of the material is selected; and a laser beam having a selected wavelength corresponding to the at least one selected characteristic of the material is generated. Values of the DOE are calculated corresponding to the at least one selected characteristic of the material. The beam and the DOE are modulated to produce a holographic optical trap having properties corresponding to the at least one selected characteristic; the trap is focused to a beam focus or selected spot size; and the beam focus is located near a particle location for trapping the particle therein.

Abstract: The present invention employs a beam steering apparatus to isolate valuable cells from other cells, tissues, and contaminants. In one embodiment, the system balances optical trapping against biasing flow to parallelize cell sorting under the flexible control of computer program-directed traps which differentially manipulate cells based on their composition or labels to direct separation.