Abstract: The present invention is directed to mutant Salmonella sp. having a genetically modified msbB gene in which the mutant Salmonella is capable of targeting solid tumors. The invention is also directed to Salmonella sp. containing a genetically modified msbB gene as well as an genetic modification in a biosynthetic pathway gene such as the purI gene. The present invention further relates to the therapeutic use of the mutant Salmonella for growth inhibition and/or reduction in volume of solid tumors.

Abstract: The invention is directed to mutant Salmonella sp. having a genetically modified msbB gene in which the mutant Salmonella is capable of targeting solid tumors. The invention further relates to the therapeutic use of the mutant Salmonella for growth inhibition and/or reduction in volume of solid tumors.

Abstract: The present invention is directed to mutant Salmonella sp. having a genetically modified msbB gene in which the mutant Salmonella is capable of targeting solid tumors. The invention is also directed to Salmonella sp. containing a genetically modified msbB gene as well as an genetic modification in a biosynthetic pathway gene such as the purI gene. The present invention further relates to the therapeutic use of the mutant Salmonella for growth inhibition and/or reduction in volume of solid tumors.

Abstract: The present invention is directed to mutant Salmonella sp. having a genetically modified msbB gene in which the mutant Salmonella is capable of targeting solid tumors. The invention is also directed to Salmonella sp. containing a genetically modified msbB gene as well as an genetic modification in a biosynthetic pathway gene such as the purl gene. The present invention further relates to the therapeutic use of the mutant Salmonella for growth inhibition and/or reduction in volume of solid tumors.

Abstract: The present invention is directed to the isolation and use of super-infective, tumor-specific vectors that are strains of parasites including, but not limited to bacteria, fungi and protists. In certain embodiments the parasites include, but are not limited to, the bacterium Salmonella spp., such as Salmonella typhimurium, the bacterium Mycobacterium avium and the protozoan Leishmania amazonensis. In other embodiments, the present invention is concerned with the isolation of super-infective, tumor-specific, suicide gene-containing strains of parasites for use in treatment of solid tumors.

Abstract: The present invention is directed to mutant Salmonella sp. having a genetically modified msbB gene in which the mutant Salmonella is capable of targeting solid tumors. The present invention further relates to the therapeutic use of the mutant Salmonella for growth inhibition and/or reduction in volume of solid tumors.

Abstract: Method and apparatus for crimping a round tenon for furniture manufacture, utilizing a crimping roll cluster consisting of a knurled drive roll and two idler compressing rolls. The apparatus includes means for feeding a wooden workpiece into and out of axial alignment with the crimping roll cluster; means for pressing the wooden workpiece into engagement with the knurled portion of the drive roll; means for rotating the workpiece from one to two revolutions, thus forming flutes into the tenon; and means for discharging the workpiece from the apparatus.Also disclosed is a method and apparatus for fluting a workpiece having tenons on both ends.

Abstract: A single or multi-orifice metal nozzle structure suitable for use in an ink jet printing system. The metallic nozzle member has at least one orifice extending therethrough, the orifice including a cylindrical portion, adjacent the outlet face of said nozzle, having a height ranging from 0.25 to 5 times its diameter and at least one frustoconical section divergent toward the face opposite the outlet face and communicating with the cylindrical portion. Where the metal nozzle is a multi-orifice metal nozzle, each frustoconical section communicates with a groove disposed in the face opposite the outlet face. The multi-orifice metal nozzle is prepared by grooving a metal plate with at least one groove, punching a plurality of frustoconical sections into the groove member and then forming a cylindrical portion into each frustoconical section and through the plate member.

Abstract: A single or multi-orifice metal nozzle structure suitable for use in an ink jet printing system. The metallic nozzle member has at least one orifice extending therethrough, the orifice including a cylindrical portion, adjacent the outlet face of said nozzle, having a height ranging from 0.25 to 5 times its diameter and at least one frustoconical section divergent toward the face opposite the outlet face and communicating with the cylindrical portion. Where the metal nozzle is a multi-orifice metal nozzle, each frustoconical section communicates with a groove disposed in the face opposite the outlet face. The multi-orifice metal nozzle is prepared by grooving a metal plate with at least one groove, punching a plurality of frustoconical sections into the groove member and then forming a cylindrical portion into each frustoconical section and through the plate member.

Abstract: A composition for flocculating filler in aqueous suspension for use in papermaking, comprising a starch, an organic polyelectrolyte capable of flocculating mineral filler particles in aqueous suspension, and at least one agent capable of regulating the mobility of a dispersion, particularly a substance moderating flocculation of suspended filler or a substance moderating the viscosity of the dispersion.