Patents by Inventor Kenneth C. Appell

Kenneth C. Appell has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compositions and methods for treating ophthalmic, octic, or nasal infections
    Patent number: 9993483
    Abstract: The present invention relates to methods for treating an ophthalmic, otic, or nasal infection comprising treating the infected tissue with a composition comprising finafloxacin or a finafloxacin derivative. The present invention also relates to antimicrobial compositions comprising finafloxacin or a finafloxacin derivative. The compositions are suitable for the treatment of ophthalmic, otic, or nasal infections.
    Type: Grant
    Filed: July 27, 2015
    Date of Patent: June 12, 2018
    Assignee: Alcon Research, Ltd.
    Inventors: David W. Stroman, Masood A. Chowhan, Kenneth C. Appell
  • TOPICAL OCULAR ANALGESIC AGENTS
    Publication number: 20160089375
    Abstract: The topical ophthalmic use of certain 2,4-diamino-substituted 1,3-triazines for preventing or alleviating ocular pain in patients is disclosed. Topical ocular pharmaceutical composition are also disclosed.
    Type: Application
    Filed: October 9, 2015
    Publication date: March 31, 2016
    Inventors: Martha E. Gadd, Peter G. Klimko, Karen C. David, Kenneth C. Appell, Mark R. Hellberg
  • COMPOSITIONS AND METHODS FOR TREATING OPHTHALMIC, OCTIC, OR NASAL INFECTIONS
    Publication number: 20150328229
    Abstract: The present invention relates to methods for treating an ophthalmic, otic, or nasal infection comprising treating the infected tissue with a composition comprising finafloxacin or a finafloxacin derivative. The present invention also relates to antimicrobial compositions comprising finafloxacin or a finafloxacin derivative. The compositions are suitable for the treatment of ophthalmic, otic, or nasal infections.
    Type: Application
    Filed: July 27, 2015
    Publication date: November 19, 2015
    Inventors: David W. Stroman, Masood A. Chowhan, Kenneth C. Appell
  • Topical ocular analgesic agents
    Patent number: 9187468
    Abstract: The topical ophthalmic use of certain 2,4-diamino-substituted 1,3-triazines for preventing or alleviating ocular pain in patients is disclosed. Topical ocular pharmaceutical composition are also disclosed.
    Type: Grant
    Filed: February 13, 2014
    Date of Patent: November 17, 2015
    Assignee: NOVARTIS AG
    Inventors: Martha E. Gadd, Peter G. Klimko, Karen C. David, Kenneth C. Appell, Mark R. Hellberg
  • Methods for treating otic infections
    Patent number: 9119859
    Abstract: The present invention relates to methods for treating an ophthalmic, otic, or nasal infection comprising treating the infected tissue with a composition comprising finafloxacin or a finafloxacin derivative. The present invention also relates to antimicrobial compositions comprising finafloxacin or a finafloxacin derivative. The compositions are suitable for the treatment of ophthalmic, otic, or nasal infections.
    Type: Grant
    Filed: August 15, 2013
    Date of Patent: September 1, 2015
    Assignee: Alcon Research, Ltd.
    Inventors: David W. Stroman, Masood A. Chowhan, Kenneth C. Appell
  • TOPICAL OCULAR ANALGESIC AGENTS
    Publication number: 20140228338
    Abstract: The topical ophthalmic use of certain 2,4-diamino-substituted 1,3-triazines for preventing or alleviating ocular pain in patients is disclosed. Topcial ocular pharmaceutical composition are also disclosed.
    Type: Application
    Filed: February 13, 2014
    Publication date: August 14, 2014
    Applicant: Novartis AG
    Inventors: Martha E. Gadd, Peter G. Klimko, Karen C. David, Kenneth C. Appell, Mark R. Hellberg
  • COMPOSITIONS AND METHODS FOR TREATING OPHTHALMIC, OTIC, OR NASAL INFECTIONS
    Publication number: 20130331385
    Abstract: The present invention relates to methods for treating an ophthalmic, otic, or nasal infection comprising treating the infected tissue with a composition comprising finafloxacin or a finafloxacin derivative. The present invention also relates to antimicrobial compositions comprising finafloxacin or a finafloxacin derivative. The compositions are suitable for the treatment of ophthalmic, otic, or nasal infections.
    Type: Application
    Filed: August 15, 2013
    Publication date: December 12, 2013
    Applicant: Alcon Research, Ltd.
    Inventors: David W. Stroman, Masood A. Chowhan, Kenneth C. Appell
  • Methods for treating ophthalmic, otic, or nasal infections
    Patent number: 8536167
    Abstract: The present invention relates to methods for treating an ophthalmic, otic, or nasal infection comprising treating the infected tissue with a composition comprising finafloxacin or a finafloxacin derivative. The present invention also relates to antimicrobial compositions comprising finafloxacin or a finafloxacin derivative. The compositions are suitable for the treatment of ophthalmic, otic, or nasal infections.
    Type: Grant
    Filed: July 2, 2010
    Date of Patent: September 17, 2013
    Assignee: Alcon Research, Ltd.
    Inventors: David W. Stroman, Masood A. Chowhan, Kenneth C. Appell
  • COMPOSITIONS AND METHODS FOR TREATING OPHTHALMIC, OTIC, OR NASAL INFECTIONS
    Publication number: 20110003803
    Abstract: The present invention relates to methods for treating an ophthalmic, otic, or nasal infection comprising treating the infected tissue with a composition comprising finafloxacin or a finafloxacin derivative. The present invention also relates to antimicrobial compositions comprising finafloxacin or a finafloxacin derivative. The compositions are suitable for the treatment of ophthalmic, otic, or nasal infections.
    Type: Application
    Filed: July 2, 2010
    Publication date: January 6, 2011
    Applicant: ALCON RESEARCH, LTD.
    Inventors: David W. Stroman, Masood A. Chowhan, Kenneth C. Appell
  • 2-(aminomethyl) arylamide analgesics
    Patent number: 7084154
    Abstract: A chemical genus of 2-(aminomethyl)arylamides, which are useful as analgesics, is disclosed.
    Type: Grant
    Filed: February 11, 2003
    Date of Patent: August 1, 2006
    Assignee: Pharmacopeia Drug Disclovery, Inc.
    Inventors: Koc-Kan Ho, John J. Baldwin, Adolph C. Bohnstedt, Steven G. Kultgen, Edward McDonald, Tao Guo, John Richard Morphy, Zoran Rankovic, Robert Horlick, Kenneth C. Appell
  • 2-(aminomethyl) arylamide analgesics
    Publication number: 20040167119
    Abstract: A chemical genus of 2-(aminomethyl)arylamides, which are useful as analgesics, is disclosed.
    Type: Application
    Filed: February 11, 2003
    Publication date: August 26, 2004
    Applicant: PHARMACOPEIA, INC
    Inventors: Koc-Kan Ho, John J. Baldwin, Adolph C. Bohnstedt, Steven G. Kultgen, Edward McDonald, Tao Guo, John Richard Morphy, Zoran Rankovic, Robert Horlick, Kenneth C. Appell
  • Site-specific bioconjugates of chemokines and their use in assays
    Patent number: 6156520
    Abstract: The present invention encompasses polypeptides that comprise a chemokine receptor binding sequence and are useful in determining the affinity of a compound for a chemokine receptor. Substitution of one of the amino acids of the C-terminal region of the polypeptide with a cysteine enables the polypeptide to be detectably labelled without loss of receptor binding activity and without the problems inherent in radioiodine labelling. Methods for use of the polypeptides in competitive binding assays are also disclosed.
    Type: Grant
    Filed: August 15, 1997
    Date of Patent: December 5, 2000
    Assignee: Pharmacopeia, Inc.
    Inventors: James Inglese, Kenneth C. Appell, Philippe Samama, Ilana L. Stroke, Jonathan J. Burbaum