Patents by Inventor Kenneth Jeffrey
Kenneth Jeffrey has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240094233Abstract: The present invention relates to methods, devices and systems for associating consumable data with an assay consumable used in a biological assay. Provided are assay systems and associated consumables, wherein the assay system adjusts one or more steps of an assay protocol based on consumable data specific for that consumable. Various types of consumable data are described, as well as methods of using such data in the conduct of an assay by an assay system. The present invention also relates to consumables (e.g., kits and reagent containers), software, data deployable bundles, computer-readable media, loading carts, instruments, systems, and methods, for performing automated biological assays.Type: ApplicationFiled: July 18, 2023Publication date: March 21, 2024Inventors: Jacob N. WOHLSTADTER, Manish KOCHAR, Peter J. BOSCO, Ian D. CHAMBERLIN, Bandele JEFFREY-COKER, Eric M. JONES, Gary I. KRIVOY, Don E. KRUEGER, Aaron H. LEIMKUEHLER, Pei-Ming WU, Kim-Xuan NGUYEN, Pankaj OBEROI, Louis W. PANG, Jennifer PARKER, Victor PELLICIER, Nicholas SAMMONS, George SIGAL, Michael L. VOCK, Stanley T. SMITH, Carl C. STEVENS, Rodger D. OSBORNE, Kenneth E. PAGE, Michael T. WADE, Jon WILLOUGHBY, Lei WANG, Xinri CONG, Kin NG
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Patent number: 11913685Abstract: Provided is a chiller and system that may be utilized in a supercritical fluid chromatography method, wherein a non-polar solvent may replace a portion or all of a polar solvent for the purpose of separating or extracting desired sample molecules from a combined sample/solvent stream. The system may reduce the amount of polar solvent necessary for chromatographic separation and/or extraction of desired samples. The system may incorporate a supercritical fluid chiller, a supercritical fluid pressure-equalizing vessel and a supercritical fluid cyclonic separator. The supercritical fluid chiller allows for efficient and consistent pumping of liquid-phase gases employing off-the-shelf HPLC pumps. The pressure equalizing vessel allows the use of off-the-shelf HPLC column cartridges. The system may further incorporate the use of one or more disposable cartridges containing silica gel or other suitable medium.Type: GrantFiled: October 20, 2021Date of Patent: February 27, 2024Assignee: Supercritical Fluid Technologies, Inc.Inventors: Kenneth Joseph James, Brian Jeffrey Waibel, Kenneth Richard Krewson, Kim Ferrara, Curtis Ebersold
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Publication number: 20230054307Abstract: A finger mounted vacuum pickup tool for picking up a material may include a finger band configured to accommodate insertion of a user’s finger therein; a ring cap attached to the finger band; and a vacuum cup attached to the ring cap, the vacuum cup including a cup portion and a protrusion extending from a rear surface of the cup portion, the protrusion having a vacuum cup channel extending therethrough, wherein the vacuum cup is configured to create a vacuum seal against the material. The ring cap may include a ring cap inlet channel extending from the vacuum cup to a vent port. The tool may further include an actuation button positioned within the vent port or a vacuum supply tube operatively attached to the ring cap.Type: ApplicationFiled: August 16, 2022Publication date: February 23, 2023Inventor: Kenneth Jeffrey Nelson
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Patent number: 11085853Abstract: Methods, apparatuses and systems for facilitating automated or semi-automated collection of tissue samples cut by a microtome. In one example, a collection apparatus may be moved back and forth between respective positions at which the collection apparatus is operatively coupled to a microtome so as to collect cut tissue samples, or routine access to the microtome is provided. Relatively easy movement and positioning of the collection apparatus is facilitated, while at the same time ensuring structural stability and appropriate alignment and/or isolation between the collection apparatus and the microtome. A fluid reservoir receives samples cut by the microtome, and the collection apparatus may collect samples via a conveyor-like substrate disposed near/in the reservoir. A linear movement of the substrate may be controlled based on a cutting rate of the microtome, and the fluid level in the reservoir may be automatically maintained to facilitate effective sample collection.Type: GrantFiled: July 6, 2020Date of Patent: August 10, 2021Assignee: President and Fellows of Harvard CollegeInventors: Kenneth Jeffrey Hayworth, Richard Schalek, Juan Carlos Tapia, Narayanan Kasthuri, Jeff W. Lichtman
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Patent number: 11042773Abstract: Systems and methods for detecting a user's finger are provided. In some embodiments, a method may include applying a first electrical signal, applying a second signal, receiving a third electrical signal using a first electrode, receiving a fourth electrical signal using the first electrode, extracting the third and fourth electrical signals using a quadrature demodulator, and compensating for a phase delay between at least the first electrical signal and the third electrical signal.Type: GrantFiled: January 11, 2019Date of Patent: June 22, 2021Assignee: IDEX BIOMETRICS ASAInventors: Jeffrey A Small, Kenneth Jeffrey Stern
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Publication number: 20200393332Abstract: Methods, apparatuses and systems for facilitating automated or semi-automated collection of tissue samples cut by a microtome. In one example, a collection apparatus may be moved back and forth between respective positions at which the collection apparatus is operatively coupled to a microtome so as to collect cut tissue samples, or routine access to the microtome is provided. Relatively easy movement and positioning of the collection apparatus is facilitated, while at the same time ensuring structural stability and appropriate alignment and/or isolation between the collection apparatus and the microtome. A fluid reservoir receives samples cut by the microtome, and the collection apparatus may collect samples via a conveyor-like substrate disposed near/in the reservoir. A linear movement of the substrate may be controlled based on a cutting rate of the microtome, and the fluid level in the reservoir may be automatically maintained to facilitate effective sample collection.Type: ApplicationFiled: July 6, 2020Publication date: December 17, 2020Inventors: KENNETH JEFFREY HAYWORTH, Richard Schalek, Juan Carlos Tapia, Narayanan Kasthuri, Jeff W. Lichtman
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Publication number: 20200226412Abstract: Systems and methods for detecting a user's finger are provided. In some embodiments, a method may include applying a first electrical signal, applying a second signal, receiving a third electrical signal using a first electrode, receiving a fourth electrical signal using the first electrode, extracting the third and fourth electrical signals using a quadrature demodulator, and compensating for a phase delay between at least the first electrical signal and the third electrical signal.Type: ApplicationFiled: January 11, 2019Publication date: July 16, 2020Applicant: IDEX ASAInventors: Jeffrey A. SMALL, Kenneth Jeffrey STERN
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Patent number: 10704992Abstract: Methods, apparatuses and systems for facilitating automated or semi-automated collection of tissue samples cut by a microtome. In one example, a collection apparatus may be moved back and forth between respective positions at which the collection apparatus is operatively coupled to a microtome so as to collect cut tissue samples, or routine access to the microtome is provided. Relatively easy movement and positioning of the collection apparatus is facilitated, while at the same time ensuring structural stability and appropriate alignment and/or isolation between the collection apparatus and the microtome. A fluid reservoir receives samples cut by the microtome, and the collection apparatus may collect samples via a conveyor-like substrate disposed near/in the reservoir. A linear movement of the substrate may be controlled based on a cutting rate of the microtome, and the fluid level in the reservoir may be automatically maintained to facilitate effective sample collection.Type: GrantFiled: April 26, 2019Date of Patent: July 7, 2020Assignee: President and Fellows of Harvard CollegeInventors: Kenneth Jeffrey Hayworth, Richard Schalek, Juan Carlos Tapia, Narayanan Kasthuri, Jeff W. Lichtman
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Patent number: 10691258Abstract: Systems and methods for reducing noise in sensors are described. In some embodiments, measurement values for selected pixels may be processed to remove signals that are common to groups of pixels. In some embodiments, offset values between pixel groups may be determined. In some embodiments, the determined offset values may be used to remove or suppress artificial discontinuities.Type: GrantFiled: January 12, 2018Date of Patent: June 23, 2020Assignee: IDEX Biometrics ASAInventors: Jeffrey A Small, Kenneth Jeffrey Stern, Imre Knausz
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Patent number: 10486301Abstract: Example overstock audit tools and associated methods are described. The example overstock audit tool includes a body defining a distal end and a proximal end, and a cutout formed in the body and extending from the proximal end. The cutout can be configured and dimensioned to be placed against a shelf edge to align the handle portion with the shelf edge. The overstock audit tool includes an elongated portion attached to and extending from the handle portion. An example overstock audit tool can include a roller mechanism configured to slidably secure the handle portion to the shelf edge.Type: GrantFiled: April 11, 2017Date of Patent: November 26, 2019Assignee: Walmart Apollo, LLCInventors: Robert James Taylor, Jason Bellar, Kenneth Jeffrey Dobbs, Matthew David Alexander, Leigh Ann Marie Scobey, Jamison Lonnie Kyle Sibley, William C. Maestas
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Publication number: 20190250071Abstract: Methods, apparatuses and systems for facilitating automated or semi-automated collection of tissue samples cut by a microtome. In one example, a collection apparatus may be moved back and forth between respective positions at which the collection apparatus is operatively coupled to a microtome so as to collect cut tissue samples, or routine access to the microtome is provided. Relatively easy movement and positioning of the collection apparatus is facilitated, while at the same time ensuring structural stability and appropriate alignment and/or isolation between the collection apparatus and the microtome. A fluid reservoir receives samples cut by the microtome, and the collection apparatus may collect samples via a conveyor-like substrate disposed near/in the reservoir. A linear movement of the substrate may be controlled based on a cutting rate of the microtome, and the fluid level in the reservoir may be automatically maintained to facilitate effective sample collection.Type: ApplicationFiled: April 26, 2019Publication date: August 15, 2019Applicant: President and Fellows of Harvard CollegeInventors: Kenneth Jeffrey Hayworth, Richard Schalek, Juan Carlos Tapia, Narayanan Kasthuri, Jeff W. Lichtman
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Publication number: 20190220141Abstract: Systems and methods for reducing noise in sensors are described. In some embodiments, measurement values for selected pixels may be processed to remove signals that are common to groups of pixels. In some embodiments, offset values between pixel groups may be determined. In some embodiments, the determined offset values may be used to remove or suppress artificial discontinuities.Type: ApplicationFiled: January 12, 2018Publication date: July 18, 2019Applicant: IDEX ASAInventors: Jeffrey A. Small, Kenneth Jeffrey Stern, Imre Knausz
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Patent number: 10288532Abstract: Methods, apparatuses and systems for facilitating automated or semi-automated collection of tissue samples cut by a microtome. In one example, a collection apparatus may be moved back and forth between respective positions at which the collection apparatus is operatively coupled to a microtome so as to collect cut tissue samples, or routine access to the microtome is provided. Relatively easy movement and positioning of the collection apparatus is facilitated, while at the same time ensuring structural stability and appropriate alignment and/or isolation between the collection apparatus and the microtome. A fluid reservoir receives samples cut by the microtome, and the collection apparatus may collect samples via a conveyor-like substrate disposed near/in the reservoir. A linear movement of the substrate may be controlled based on a cutting rate of the microtome, and the fluid level in the reservoir may be automatically maintained to facilitate effective sample collection.Type: GrantFiled: August 7, 2017Date of Patent: May 14, 2019Assignee: President and Fellows of Harvard CollegeInventors: Kenneth Jeffrey Hayworth, Richard Schalek, Juan Carlos Tapia, Narayanan Kasthuri, Jeff Lichtman
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Patent number: 9927327Abstract: Methods, apparatus and systems for collecting thin tissue samples for imaging. Thin tissue sections may be cut from tissue samples using a microtome-quality knife. In one example, tissue samples are mounted to a substrate that is rotated such that thin tissue sections are acquired via lathing. Collection of thin tissue sections may be facilitated by a conveyor belt. Thin tissue sections may be mounted to a thin substrate (e.g., by adhering thin tissue sections to a thin substrate via a roller mechanism) that may be imaged, for example, by an electron beam (e.g., in an electron microscope). Thin tissue sections may be strengthened before cutting via a blockface thinfilm deposition technique and/or a blockface taping technique. An automated reel-to-reel imaging technique may be employed for collected/mounted tissue sections to facilitate random-access imaging of tissue sections and maintaining a comprehensive library including a large volume of samples.Type: GrantFiled: January 25, 2016Date of Patent: March 27, 2018Assignee: President and Fellows of Harvard CollegeInventors: Kenneth Jeffrey Hayworth, Amy Au Hayworth
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Publication number: 20180080856Abstract: Methods, apparatuses and systems for facilitating automated or semi-automated collection of tissue samples cut by a microtome. In one example, a collection apparatus may be moved back and forth between respective positions at which the collection apparatus is operatively coupled to a microtome so as to collect cut tissue samples, or routine access to the microtome is provided. Relatively easy movement and positioning of the collection apparatus is facilitated, while at the same time ensuring structural stability and appropriate alignment and/or isolation between the collection apparatus and the microtome. A fluid reservoir receives samples cut by the microtome, and the collection apparatus may collect samples via a conveyor-like substrate disposed near/in the reservoir. A linear movement of the substrate may be controlled based on a cutting rate of the microtome, and the fluid level in the reservoir may be automatically maintained to facilitate effective sample collection.Type: ApplicationFiled: August 7, 2017Publication date: March 22, 2018Inventors: Kenneth Jeffrey Hayworth, Richard Schalek, Juan Carlos Tapia, Narayanan Kasthuri, Jeff Lichtman
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Patent number: 9839940Abstract: A tool for depositing multilayer coatings onto a substrate. The tool includes a housing defining a vacuum chamber connected to a vacuum source, deposition stations each configured to deposit a layer of multilayer coating on the substrate, a curing station, and a contamination reduction device. At least one of the deposition stations is configured to deposit an inorganic layer, while at least one other deposition station is configured to deposit an organic layer. In one tool configuration, the substrate may travel back and forth through the tool as many times as needed to achieve the desired number of layers of multilayer coating. In another, the tool may include numerous housings adjacently spaced such that the substrate may make a single unidirectional pass. The contamination reduction device may be configured as one or more migration control chambers about at least one of the deposition stations, and further includes cooling devices, such as chillers, to reduce the presence of vaporous layer precursors.Type: GrantFiled: October 9, 2013Date of Patent: December 12, 2017Assignee: Samsung Display Co., Ltd.Inventors: Charles C. Bonham, Paul E. Burrows, Xi Chu, Gordon Lee Graff, Mark Edward Gross, Peter Maclyn Martin, Lorenza Moro, Kenneth Jeffrey Nelson, John Chris Pagano, Mac R. Zumhoff
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Publication number: 20170291294Abstract: Example overstock audit tools and associated methods are described. The example overstock audit tool includes a body defining a distal end and a proximal end, and a cutout formed in the body and extending from the proximal end. The cutout can be configured and dimensioned to be placed against a shelf edge to align the handle portion with the shelf edge. The overstock audit tool includes an elongated portion attached to and extending from the handle portion. An example overstock audit tool can include a roller mechanism configured to slidably secure the handle portion to the shelf edge.Type: ApplicationFiled: April 11, 2017Publication date: October 12, 2017Inventors: Robert James Taylor, Jason Bellar, Kenneth Jeffrey Dobbs, Matthew David Alexander, Leigh Ann Marie Scobey, Jamison Lonnie Kyle Sibley, William C. Maestas
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Patent number: 9784648Abstract: Methods, apparatuses and systems for facilitating automated or semi-automated collection of tissue samples cut by a microtome. In one example, a collection apparatus may be moved back and forth between respective positions at which the collection apparatus is operatively coupled to a microtome so as to collect cut tissue samples, or routine access to the microtome is provided. Relatively easy movement and positioning of the collection apparatus is facilitated, while at the same time ensuring structural stability and appropriate alignment and/or isolation between the collection apparatus and the microtome. A fluid reservoir receives samples cut by the microtome, and the collection apparatus may collect samples via a conveyor-like substrate disposed near/in the reservoir. A linear movement of the substrate may be controlled based on a cutting rate of the microtome, and the fluid level in the reservoir may be automatically maintained to facilitate effective sample collection.Type: GrantFiled: September 7, 2011Date of Patent: October 10, 2017Assignee: President and Fellows of Harvard CollegeInventors: Kenneth Jeffrey Hayworth, Richard Schalek, Juan Carlos Tapia, Narayanan Kasthuri, Jeff Lichtman
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Publication number: 20160139007Abstract: Methods, apparatus and systems for collecting thin tissue samples for imaging. Thin tissue sections may be cut from tissue samples using a microtome-quality knife. In one example, tissue samples are mounted to a substrate that is rotated such that thin tissue sections are acquired via lathing. Collection of thin tissue sections may be facilitated by a conveyor belt. Thin tissue sections may be mounted to a thin substrate (e.g., by adhering thin tissue sections to a thin substrate via a roller mechanism) that may be imaged, for example, by an electron beam (e.g., in an electron microscope). Thin tissue sections may be strengthened before cutting via a blockface thinfilm deposition technique and/or a blockface taping technique. An automated reel-to-reel imaging technique may be employed for collected/mounted tissue sections to facilitate random-access imaging of tissue sections and maintaining a comprehensive library including a large volume of samples.Type: ApplicationFiled: January 25, 2016Publication date: May 19, 2016Applicant: President and Fellows of Harvard CollegeInventors: Kenneth Jeffrey Hayworth, Amy Au Hayworth
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Patent number: 9304067Abstract: Methods, apparatus and systems for collecting thin tissue samples for imaging. Thin tissue sections may be cut from tissue samples using a microtome-quality knife. In one example, tissue samples are mounted to a substrate that is rotated such that thin tissue sections are acquired via lathing. Collection of thin tissue sections may be facilitated by a conveyor belt. Thin tissue sections may be mounted to a thin substrate (e.g., by adhering thin tissue sections to a thin substrate via a roller mechanism) that may be imaged, for example, by an electron beam (e.g., in an electron microscope). Thin tissue sections may be strengthened before cutting via a blockface thinfilm deposition technique and/or a blockface taping technique. An automated reel-to-reel imaging technique may be employed for collected/mounted tissue sections to facilitate random-access imaging of tissue sections and maintaining a comprehensive library including a large volume of samples.Type: GrantFiled: January 4, 2013Date of Patent: April 5, 2016Assignee: President and Fellows of Harvard CollegeInventors: Kenneth Jeffrey Hayworth, Amy Au Hayworth