Abstract: Systems, methods and software merge a Virtual World, Live Event and Entertainment Channel, thus creating “The Perfect Storm” of gaming and entertainment whereby the characters of a social network game (e.g., an online fantasy sports league) are represented by human beings who register to be avatars of characters supported by a “Character Service Center,” while players compete to bring avatars to life in a Real World event (e.g., a Real World sports league), where the human beings behind the avatars compete for prizes while staying in character, as these competitors and players are incentivized by a “Collaboration Incentive Platform.

Abstract: Systems, methods and software merge a Virtual World, Live Event and Entertainment Channel, thus creating “The Perfect Storm” of gaming and entertainment whereby the characters of a social network game (e.g., an online fantasy sports league) are represented by human beings who register to be avatars of characters supported by a “Character Service Center,” while players compete to bring avatars to life in a Real World event (e.g., a Real World sports league), where the human beings behind the avatars compete for prizes while staying in character, as these competitors and players are incentivized by a “Collaboration Incentive Platform.

Abstract: Disclosed herein are compositions including a compound of formula (I) for treating cancer. Some embodiments relate to methods of treating cancer by co-administering a compound of formula (I) and one or more immune checkpoint inhibitor to a subject in need thereof. Some embodiments relate to methods of treating cancer by co-administering a compound of formula (I) and plinabulin to a subject in need thereof. Some embodiments relate to methods of providing co-stimulation of T-cell activation against cancer by co-administering a compound of formula (I), one or more immune checkpoint inhibitor.

Abstract: Disclosed herein are methods of reducing or preventing thrombocytopenia, in a clinically relevant manner, that is caused by chemotherapy or radiation therapy by administering plinabulin to a subject.

Abstract: A moving energy absorbing component includes an impact head including a base and upright projection. The base includes an axial orifice extending from a downstream entry point to an upstream exit point, through which an upstream terminus of an FTE rail is passed before the FTE rail is directly or indirectly connected to a releasable connection point coupled to a ground anchor. The impact head is connected via at least one beam to a post detacher element located downstream of the impact head a pre-determined distance therefrom.

Abstract: A cover board and roofing system including a cover board are disclosed. In one embodiment, the cover board includes a honeycomb layer positioned between a first face sheet and a second face sheet. The honeycomb layer comprises a honeycomb structure having a plurality of partition walls forming a plurality of cells. When the cover board is applied as part of a roof structure, including an insulation layer and a roof deck below the cover board, the roof structure exceeds requirements for Very Severe Hail Resistance according to the FM Approvals FM 4470 VSH impact resistance testing standard for Single-Ply, Polymer-Modified Bitumen Sheet, Built-Up Roof (BUR) and Liquid Applied Roof Assemblies.

Abstract: A cover board and roofing system including a cover board are disclosed. In one embodiment, the cover board includes a core having a first surface and a second surface. The core is configured to overlie a roof substrate. The cover board includes at least one facer attached to the first surface, the second surface, or both the first surface and second surface of the core. The cover board includes a reinforcing layer positioned between the core and the at least one facer. The reinforcing layer may comprise a scrim material. An impact resistance of the cover board may be greater than an impact resistance of an identical cover board without the scrim material.

Abstract: A grounds maintenance vehicle having a vehicle frame is disclosed. An implement is coupled to the vehicle frame and has a first implement end and a second implement end. A height selection tool is configured to select one vertical position of a plurality of selectable vertical positions, where each vertical position limits a distance between the implement and the vehicle frame. An implement angle selection tool is configured to change the elevation of the first implement end relative to the second implement end and fix the elevation of the first implement end relative the second implement end. The implement angle selection tool has a manually engageable mechanism configured to change the elevation of the first implement end relative to the second implement end when the implement angle selection tool is disengaged.

Abstract: Disclosed herein are plinabulin and the use for reducing neutropenia. Some embodiments relate to reducing the docetaxel induced neutropenia using plinabulin.

Abstract: A moving energy absorbing component includes an impact head including a base and upright projection. The base includes an axial orifice extending from a downstream entry point to an upstream exit point, through which an upstream terminus of an FTE rail is passed before the FTE rail is directly or indirectly connected to a releasable connection point coupled to a ground anchor. The impact head is connected via at least one beam to a post detacher element located downstream of the impact head a pre-determined distance therefrom.

Abstract: Disclosed herein are plinabulin and the use for reducing neutropenia. Some embodiments relate to reducing the docetaxel induced neutropenia using plinabulin.

Abstract: A road safety rail system comprising at least one continuous rail, or a plurality of sequentially connected system rails, forming a main body of a barrier, which are supported above ground by one or more ground engaging posts, wherein the system also comprises a terminal end section (TES) having an upstream end and a downstream end, the TES including: a stationary component comprising one or more standard terminal end (STE)-rails at the downstream end connected to at least one formed terminal end (FTE)-rail located at the upstream end of the TES, the STE rails being supported at a set horizontal axis height above ground level by a plurality of posts; wherein the at least one FTE-rail(s)-include(s) a twist from a primarily vertical orientation to a primarily horizontal orientation; Wherein the at least one FTE rail(s) bends down from a set horizontal axis height Y above ground level to a horizontal axis height being at, or near ground level; a moving energy absorbing component comprising an impact head incl

Abstract: Disclosed herein are methods of reducing neutropenia that is caused by chemotherapy or radiation therapy by administering plinabulin to a subject.

Abstract: Disclosed herein are methods of reducing neutropenia that is caused by chemotherapy or radiation therapy by administering plinabulin to a subject.

Abstract: Systems, methods and software merge a Virtual World, Live Event and Entertainment Channel, thus creating “The Perfect Storm” of gaming and entertainment whereby the characters of a social network game (e.g., an online fantasy sports league) are represented by human beings who register to be avatars of characters supported by a “Character Service Center,” while players compete to bring avatars to life in a Real World event (e.g., a Real World sports league), where the human beings behind the avatars compete for prizes while staying in character, as these competitors and players are incentivized by a “Collaboration Incentive Platform.

Abstract: A road safety rail system comprising at least one continuous rail, or a plurality of sequentially connected system rails, forming a main body of a barrier, which are supported above ground by one or more ground engaging posts, wherein the system also comprises a terminal end section (TES) having an upstream end and a downstream end, the TES including: a stationary component comprising one or more standard terminal end (STE)-rails at the downstream end connected to at least one formed terminal end (FTE)-rail located at the upstream end of the TES, the STE rails being supported at a set horizontal axis height above ground level by a plurality of posts; wherein the at least one FTE-rail(s)-include(s) a twist from a primarily vertical orientation to a primarily horizontal orientation; Wherein the at least one FTE rail(s) bends down from a set horizontal axis height Y above ground level to a horizontal axis height being at, or near ground level; a moving energy absorbing component comprising an impact head incl

Abstract: Systems, methods and software merge a Virtual World, Live Event and Entertainment Channel, thus creating “The Perfect Storm” of gaming and entertainment whereby the characters of a social network game (e.g., an online fantasy sports league) are represented by human beings who register to be avatars of characters supported by a “Character Service Center,” while players compete to bring avatars to life in a Real World event (e.g., a Real World sports league), where the human beings behind the avatars compete for prizes while staying in character, as these competitors and players are incentivized by a “Collaboration Incentive Platform.

Abstract: A grounds maintenance vehicle having a vehicle frame is disclosed. An implement is coupled to the vehicle frame and has a first implement end and a second implement end. A height selection tool is configured to select one vertical position of a plurality of selectable vertical positions, where each vertical position limits a distance between the implement and the vehicle frame. An implement angle selection tool has a manually engageable mechanism configured to change the elevation of one of the first implement end or the second implement end relative to the other of the first implement end or the second implement end. The implement angle selection tool is configured to fix the elevation of the first implement end relative the second implement end.

Abstract: Disclosed herein are compositions including a compound of formula (I) for treating cancer. Some embodiments relate to methods of treating cancer by co-administering a compound of formula (I) and one or more immune checkpoint inhibitor to a subject in need thereof. Some embodiments relate to methods of treating cancer by co-administering a compound of formula (I) and plinabulin to a subject in need thereof. Some embodiments relate to methods of providing co-stimulation of T-cell activation against cancer by co-administering a compound of formula (I), one or more immune checkpoint inhibitor.

Abstract: Disclosed herein are plinabulin and its use for treating a cancer or tumor characterized by expression of a mutant form of an epidermal growth factor receptor (EGFR) protein, comprising administering plinabulin to a subject in need thereof.