Patents by Inventor Kenneth R. Krieg
Kenneth R. Krieg has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240130917Abstract: Described herein are various embodiments of differential air pressure systems and methods of using and calibration such systems for individuals with impaired mobility. The differential air pressure systems may include an access assist device configured to help a mobility impaired user to stand in a pressure chamber configured to apply a positive pressure on a portion of the user's body in the sealed pressure chamber. The system may also include load sensors configured to measure the user's weight exerted inside and outside the chamber. The system may be calibrated by determining a relationship between the actual weight of the user and the pressure in the chamber, where the actual weight of the user may be measured by more than one load sensor and at least one load sensor is not in the pressure chamber.Type: ApplicationFiled: July 26, 2023Publication date: April 25, 2024Inventors: Eric Richard KUEHNE, Christopher LOEW, Glen R. MANGSETH, Kenneth R. KRIEG, David P. GRENEWETZKI, Clifford T. JUE, Trevor L. DONALD
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Patent number: 11904164Abstract: Described herein are apparatuses (e.g., systems and devices) and methods of delivering nanosecond pulsed electrical fields (nsPEF). In particular, these apparatuses and methods may provide enhanced safety and robust operation over even very short (e.g., nanosecond and sub-nanosecond pulses) and high voltage pulsing; these benefits may be accomplished by multi-functional isolation of various subsystems and components of the apparatus, even including the low-voltage, control and command portions of the apparatus with extremely low capacitance, high voltage isolation.Type: GrantFiled: July 27, 2020Date of Patent: February 20, 2024Assignee: Pulse Biosciences, Inc.Inventors: Kenneth R. Krieg, Gregory P. Schaadt, Chaofeng Huang
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Publication number: 20230381514Abstract: Described herein are apparatuses and methods for applying high voltage, sub-microsecond (e.g., nanosecond range) pulsed output to a biological material, e.g., tissues, cells, etc., using a high voltage (e.g., MOSFET) gate driver circuit having a high voltage isolation and a low inductance. In particular, described herein are multi-core pulse transformers comprising independent transformer cores arranged in parallel on opposite sides of a substrate. The transformer cores may have coaxial primary and secondary windings. Also describe are pulse generators including multi-core pulse transformers arranged in parallel (e.g., on opposite sides of a PCB) to reduce MOSFET driver gate inductance.Type: ApplicationFiled: August 7, 2023Publication date: November 30, 2023Inventors: Chaofeng HUANG, Gregory P. SCHAADT, Kenneth R. KRIEG
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Patent number: 11766563Abstract: Described herein are apparatuses and methods for applying high voltage, sub-microsecond (e.g., nanosecond range) pulsed output to a biological material, e.g., tissues, cells, etc., using a high voltage (e.g., MOSFET) gate driver circuit having a high voltage isolation and a low inductance. In particular, described herein are multi-core pulse transformers comprising independent transformer cores arranged in parallel on opposite sides of a substrate. The transformer cores may have coaxial primary and secondary windings. Also describe are pulse generators including multi-core pulse transformers arranged in parallel (e.g., on opposite sides of a PCB) to reduce MOSFET driver gate inductance.Type: GrantFiled: August 4, 2022Date of Patent: September 26, 2023Assignee: Pulse Biosciences, Inc.Inventors: Chaofeng Huang, Gregory P. Schaadt, Kenneth R. Krieg
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Patent number: 11752058Abstract: Described herein are various embodiments of differential air pressure systems and methods of using and calibration such systems for individuals with impaired mobility. The differential air pressure systems may include an access assist device configured to help a mobility impaired user to stand in a pressure chamber configured to apply a positive pressure on a portion of the user's body in the sealed pressure chamber. The system may also include load sensors configured to measure the user's weight exerted inside and outside the chamber. The system may be calibrated by determining a relationship between the actual weight of the user and the pressure in the chamber, where the actual weight of the user may be measured by more than one load sensor and at least one load sensor is not in the pressure chamber.Type: GrantFiled: October 16, 2020Date of Patent: September 12, 2023Assignee: AlterG, Inc.Inventors: Eric Richard Kuehne, Christopher Loew, Glen R. Mangseth, Kenneth R. Krieg, David P. Grenewetzki, Clifford T. Jue, Trevor L. Donald
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Publication number: 20230248415Abstract: Described herein are methods and systems for using the treatment tip apparatuses and high-voltage connectors with robotic surgical systems. For example, retractable treatment tip apparatuses (e.g., devices, systems, etc.) including one, or more preferably a plurality, of electrodes that are protected by a housing (which may be retractable) until pressed against the tissue for deployment of the electrodes and delivery of a therapeutic treatment, are disclosed. In particular, these apparatuses may include a plurality of treatment needle electrodes and may be configured for the delivery of nanosecond pulsed electric fields. Also described herein are high-voltage connectors configured to provide high-voltage energy, such as nsPEF pulses, from a generator to the retractable treatment tip apparatuses.Type: ApplicationFiled: March 20, 2023Publication date: August 10, 2023Inventors: David J. DANITZ, Cameron D. HINMAN, Kenneth R. KRIEG, Kevin L. MOSS, Christopher J. FOSTER, Darrin R. UECKER
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Publication number: 20230201572Abstract: To distribute electrical treatment to a treatment area of a patient, described herein are electrical therapy devices, methods of their operation and methods for delivery of the electrical therapy to the patient. In some embodiments, the electrical therapy device comprises an electrode assembly that includes at least two electrodes, and a conductive spacer positioned between the electrodes. Methods of selection of the electrical therapy devices and methods of their operation are also provided.Type: ApplicationFiled: December 23, 2022Publication date: June 29, 2023Applicant: Pulse Biosciences, Inc.Inventors: Cameron D. Hinman, Kenneth R. Krieg
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Patent number: 11638815Abstract: Described herein are methods and systems for using the treatment tip apparatuses and high-voltage connectors with robotic surgical systems. For example, retractable treatment tip apparatuses (e.g., devices, systems, etc.) including one, or more preferably a plurality, of electrodes that are protected by a housing (which may be retractable) until pressed against the tissue for deployment of the electrodes and delivery of a therapeutic treatment, are disclosed. In particular, these apparatuses may include a plurality of treatment needle electrodes and may be configured for the delivery of nanosecond pulsed electric fields. Also described herein are high-voltage connectors configured to provide high-voltage energy, such as nsPEF pulses, from a generator to the retractable treatment tip apparatuses.Type: GrantFiled: October 22, 2020Date of Patent: May 2, 2023Assignee: Pulse Biosciences, Inc.Inventors: David J. Danitz, Cameron D Hinman, Kenneth R. Krieg, Kevin L. Moss, Christopher J. Foster, Darrin R. Uecker
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Publication number: 20220370801Abstract: Described herein are apparatuses and methods for applying high voltage, sub-microsecond (e.g., nanosecond range) pulsed output to a biological material, e.g., tissues, cells, etc., using a high voltage (e.g., MOSFET) gate driver circuit having a high voltage isolation and a low inductance. In particular, described herein are multi-core pulse transformers comprising independent transformer cores arranged in parallel on opposite sides of a substrate. The transformer cores may have coaxial primary and secondary windings. Also describe are pulse generators including multi-core pulse transformers arranged in parallel (e.g., on opposite sides of a PCB) to reduce MOSFET driver gate inductance.Type: ApplicationFiled: August 4, 2022Publication date: November 24, 2022Inventors: Chaofeng HUANG, Gregory P. SCHAADT, Kenneth R. KRIEG
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Publication number: 20220313990Abstract: Described herein are apparatuses and methods for applying high voltage, high current, sub-microsecond (e.g., nanosecond range) pulsed output to a biological material, e.g., tissues, cells, etc., while preventing damage from load arcing. Some of the apparatuses and methods described herein may limit the load and pulsed power source current in case of load arcing significantly by using a transmission line (e.g., coaxial cable, twisted pair or parallel pair cables) between the pulsed power source and the load having a length configured to achieve this goal.Type: ApplicationFiled: September 29, 2020Publication date: October 6, 2022Inventors: Chaofeng HUANG, Gregory P. SCHAADT, Kenneth R. KRIEG
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Patent number: 11452870Abstract: Described herein are apparatuses and methods for applying high voltage, sub-microsecond (e.g., nanosecond range) pulsed output to a biological material, e.g., tissues, cells, etc., using a high voltage (e.g., MOSFET) gate driver circuit having a high voltage isolation and a low inductance. In particular, described herein are multi-core pulse transformers comprising independent transformer cores arranged in parallel on opposite sides of a substrate. The transformer cores may have coaxial primary and secondary windings. Also describe are pulse generators including multi-core pulse transformers arranged in parallel (e.g., on opposite sides of a PCB) to reduce MOSFET driver gate inductance.Type: GrantFiled: December 18, 2019Date of Patent: September 27, 2022Assignee: Pulse Biosciences, Inc.Inventors: Chaofeng Huang, Gregory P. Schaadt, Kenneth R. Krieg
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Publication number: 20220023631Abstract: Described herein are apparatuses (e.g., systems and devices) and methods of delivering nanosecond pulsed electrical fields (nsPEF). In particular, these apparatuses and methods may provide enhanced safety and robust operation over even very short (e.g., nanosecond and sub-nanosecond pulses) and high voltage pulsing; these benefits may be accomplished by multi-functional isolation of various subsystems and components of the apparatus, even including the low-voltage, control and command portions of the apparatus with extremely low capacitance, high voltage isolation.Type: ApplicationFiled: July 27, 2020Publication date: January 27, 2022Inventors: Kenneth R. KRIEG, Gregory P. SCHAADT, Chaofeng HUANG
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Publication number: 20210267833Abstract: Described herein are various embodiments of differential air pressure systems and methods of using and calibration such systems for individuals with impaired mobility. The differential air pressure systems may include an access assist device configured to help a mobility impaired user to stand in a pressure chamber configured to apply a positive pressure on a portion of the user's body in the sealed pressure chamber. The system may also include load sensors configured to measure the user's weight exerted inside and outside the chamber. The system may be calibrated by determining a relationship between the actual weight of the user and the pressure in the chamber, where the actual weight of the user may be measured by more than one load sensor and at least one load sensor is not in the pressure chamber.Type: ApplicationFiled: October 16, 2020Publication date: September 2, 2021Inventors: Eric Richard KUEHNE, Christopher LOEW, Glen R. MANGSETH, Kenneth R. KRIEG, David P. GRENEWETZKI, Clifford T. JUE, Trevor L. DONALD
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Publication number: 20210187292Abstract: Described herein are apparatuses and methods for applying high voltage, sub-microsecond (e.g., nanosecond range) pulsed output to a biological material, e.g., tissues, cells, etc., using a high voltage (e.g., MOSFET) gate driver circuit having a high voltage isolation and a low inductance. In particular, described herein are multi-core pulse transformers comprising independent transformer cores arranged in parallel on opposite sides of a substrate. The transformer cores may have coaxial primary and secondary windings. Also describe are pulse generators including multi-core pulse transformers arranged in parallel (e.g., on opposite sides of a PCB) to reduce MOSFET driver gate inductance.Type: ApplicationFiled: December 18, 2019Publication date: June 24, 2021Inventors: Chaofeng HUANG, Gregory P. SCHAADT, Kenneth R. KRIEG
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Publication number: 20210085958Abstract: Described herein are methods and systems for using the treatment tip apparatuses and high-voltage connectors with robotic surgical systems. For example, retractable treatment tip apparatuses (e.g., devices, systems, etc.) including one, or more preferably a plurality, of electrodes that are protected by a housing (which may be retractable) until pressed against the tissue for deployment of the electrodes and delivery of a therapeutic treatment, are disclosed. In particular, these apparatuses may include a plurality of treatment needle electrodes and may be configured for the delivery of nanosecond pulsed electric fields. Also described herein are high-voltage connectors configured to provide high-voltage energy, such as nsPEF pulses, from a generator to the retractable treatment tip apparatuses.Type: ApplicationFiled: October 22, 2020Publication date: March 25, 2021Inventors: David J. DANITZ, Cameron D HINMAN, Kenneth R. KRIEG, Kevin L. MOSS, Christopher J. FOSTER, Darrin R. UECKER
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Publication number: 20210038055Abstract: A method may comprise storing a first waypoint corresponding to a first position of a tip of a steerable medical device including an articulatable segment. The controller may perform a motion pause check operation to determine that an insertion motion of the articulatable segment into a patient anatomy has been paused, while the tip is at a second position. The controller may determine that the articulatable segment has resumed the insertion motion into the patient anatomy. After determining that the articulatable segment has resumed the insertion motion, a second waypoint corresponding to the second position of the tip of the steerable medical device, may be stored. A boundary region may be defined to form a three-dimensional volume enclosing the positions of the stored waypoints. The articulatable segment may be constrained to remain within the boundary region as the articulatable segment is inserted in the patient anatomy.Type: ApplicationFiled: August 21, 2020Publication date: February 11, 2021Inventors: Caitlin Q. Donhowe, Amir Belson, Kristoffer J. Donhowe, Kenneth R. Krieg, Eric Storne, Thomas J. Yorkey, Jun Zhang
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Patent number: 10857347Abstract: Described herein are methods and systems for using the treatment tip apparatuses and high-voltage connectors with robotic surgical systems. For example, retractable treatment tip apparatuses (e.g., devices, systems, etc.) including one, or more preferably a plurality, of electrodes that are protected by a housing (which may be retractable) until pressed against the tissue for deployment of the electrodes and delivery of a therapeutic treatment, are disclosed. In particular, these apparatuses may include a plurality of treatment needle electrodes and may be configured for the delivery of nanosecond pulsed electric fields. Also described herein are high-voltage connectors configured to provide high-voltage energy, such as nsPEF pulses, from a generator to the retractable treatment tip apparatuses.Type: GrantFiled: March 13, 2018Date of Patent: December 8, 2020Assignee: PULSE BIOSCIENCES, INC.Inventors: David J. Danitz, Cameron D. Hinman, Kenneth R. Krieg, Kevin L. Moss, Christopher J. Foster, Darrin R. Uecker
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Publication number: 20190099315Abstract: Described herein are various embodiments of differential air pressure systems and methods of using and calibration such systems for individuals with impaired mobility. The differential air pressure systems may include an access assist device configured to help a mobility impaired user to stand in a pressure chamber configured to apply a positive pressure on a portion of the user's body in the sealed pressure chamber. The system may also include load sensors configured to measure the user's weight exerted inside and outside the chamber. The system may be calibrated by determining a relationship between the actual weight of the user and the pressure in the chamber, where the actual weight of the user may be measured by more than one load sensor and at least one load sensor is not in the pressure chamber.Type: ApplicationFiled: May 30, 2018Publication date: April 4, 2019Inventors: Eric Richard KUEHNE, Christopher LOEW, Glen R. MANGSETH, Kenneth R. KRIEG, David P. GRENEWETZKI, Clifford T. JUE, Trevor L. DONALD
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Publication number: 20190083187Abstract: Described herein are methods and systems for using the treatment tip apparatuses and high-voltage connectors with robotic surgical systems. For example, retractable treatment tip apparatuses (e.g., devices, systems, etc.) including one, or more preferably a plurality, of electrodes that are protected by a housing (which may be retractable) until pressed against the tissue for deployment of the electrodes and delivery of a therapeutic treatment, are disclosed. In particular, these apparatuses may include a plurality of treatment needle electrodes and may be configured for the delivery of nanosecond pulsed electric fields. Also described herein are high-voltage connectors configured to provide high-voltage energy, such as nsPEF pulses, from a generator to the retractable treatment tip apparatuses.Type: ApplicationFiled: March 13, 2018Publication date: March 21, 2019Inventors: David J. Danitz, Cameron D. Hinman, Kenneth R. Krieg, Kevin L. Moss, Christopher J. Foster, Darrin R. Uecker
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Publication number: 20180333039Abstract: Waypoints for a steerable medical device are stored as the steerable medical device is moved within a patient. The stored waypoints are an ordered sequence of locations. The ordered sequence of locations defines a safe path within the patient for moving an articulatable portion of the steerable medical device. The articulatable portion of the steerable medical device is constrained to follow the safe path as the articulatable portion moves within the patient. For example, the articulatable portion of the steerable medical device is constrained to remain within a boundary region enclosing the safe path as the articulatable portion of the steerable medical device follows the safe path.Type: ApplicationFiled: July 30, 2018Publication date: November 22, 2018Inventors: Caitlin Q. Donhowe, Amir Belson, Kristoffer J. Donhowe, Kenneth R. Krieg, Eric M. Storne, Thomas J. Yorkey, Jun Zhang