Patents by Inventor Kerstin Wagner

Kerstin Wagner has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 6767635
    Abstract: The invention relates to magnetic nanoparticles, their production, and their use. The object of the invention is to provide nanoparticles capable of specifically forming bonds to intracellular biomacromolecules even in the intracellular region of cells, so that separation is possible by exposure to an exterior magnetic field. This is accomplished by means of magnetic nanoparticles having biochemical activity, consisting of a magnetic core particle and an envelope layer fixed to the core particle, and including a compound of general formula M-S-L-Z (I), the linkage sites between S and L and L and Z having covalently bound functional groups, wherein M represents said magnetic core particle; S represents a biocompatible substrate fixed to M; L represents a linker group; and Z represents a group comprised of nucleic acids, peptides or proteins or derivatives thereof, which group has at least one structure capable of specifically binding to a binding domain of an intracellular biomacromolecule.
    Type: Grant
    Filed: May 24, 2002
    Date of Patent: July 27, 2004
    Assignee: Biomedical Apherese Systeme GmbH
    Inventors: Michael Bahr, Dimitri Berkov, Norbert Buske, Joachim Clement, Peter Görnert, Klaus Höffken, Kay-Oliver Kliche, Thomas Kober, Matthias Schnabelrauch, Sebastian Vogt, Kerstin Wagner, Christian Gansau
  • Publication number: 20030044961
    Abstract: The composition for the cell-specific transfer of an active compound in specific target cells can be used as a diagnostic or therapeutic agent or for gene therapy. The composition includes virus-like particles, which are each composed of a number of viral protein molecules derived from JC virus, a cationic polymer, for example a polyamine, a polyimine or an amino acid polymer, especially polyethylenimine, as an anchor molecule for a cell-specific ligand, and preferably a ligand bound to the cationic polymer as a binding partner for a cell-specific receptor. The viral protein is advantageously encoded with a nucleic acid having nucleotide sequence as shown by SEQ. ID NO. 1.
    Type: Application
    Filed: June 26, 2002
    Publication date: March 6, 2003
    Inventors: Wolfgang Luke, Harald Petry, Oliver Ast, Ingo Wilke, Claudia Goldmann, Kerstin Wagner, Matthias Schnabelrauch