Abstract: A disposable endoscopic sleeve adapted for receiving and gripping a medical probe is provided. The endoscopic sleeve includes an elongated flexible sleeve which slides over a probe and structure for gripping the probe. The elongated flexible sleeve is formed of thin-walled corrugated synthetic resin material and presents opposed axial ends. The axial ends are connected by a hollow passageway extending between the ends. The hollow passageway presents an inside diameter slightly greater than the outside diameter of a medical probe for receiving a medical probe in the hollow passageway. When an examiner grips the sleeve, the thin-walled sleeve collapses to engage and grip the medical probe. A pair of flange members are coupled to the axial ends of the sleeve for positioning the endoscopic sleeve adjacent a patient and for preventing the sleeve from becoming contaminated by blood, body fluids, or human excrement.