Abstract: This disclosure describes embodiments of systems, methods, and non-transitory computer-readable storage media that can solve one or more of the foregoing (or other problems) in the art in addition to providing other benefits by applying customized security limitations to a secure digital account, and removing the security limitations based on efficiently verifying personal identity information associated with the secure digital account. For example, the disclosed system can receive a user interaction associated with a secure digital account and determine a fraud risk score corresponding to the interaction. The system can then assign the secure digital account a security tier and apply appropriate security limitations based on the security tier that corresponds with a determined risk of fraud.

Abstract: Provided is a system, method, and apparatus for generating analytics with structured query files. The method includes the steps of generating at least one graphical user interface configured to receive query parameters from a user for querying transaction data, generating a request file based on the query parameters, the request file including a request definition object and a segment object, processing the request file to query at least one transactional database based at least partially on the request file, and generating a response file including transaction data based on a return from the query of the at least one database, the response file structured based on the request definition object from the request file.

Abstract: A vaporizer device includes various modular components. The vaporizer device includes a first subassembly. The first subassembly includes a cartridge connector that secures a vaporizer cartridge to the vaporizer device and includes at least two receptacle contacts that electrically communicate with the vaporizer cartridge. The vaporizer device includes a second subassembly. The second subassembly includes a skeleton defining a rigid tray that retains at least a power source. The vaporizer device also includes a third subassembly. The third subassembly includes a plurality of charging contacts that supply power to the power source, and an end cap that encloses an end of the vaporizer device.

Abstract: Provided herein are methods to reduce tumor cell proliferation in a cancer patient by administering an antibody that binds angiopoietin-like 7, wherein administering the angiopoietin-like 7 antibody can reduce necrosis formation, metastasis formation, and circulating tumor cells.

Abstract: A method and system provide for computer aided drawing (CAD) automation. A CAD drawing in a first format that is native to a CAD application is obtained. Markup for the CAD drawing that is in a second non-native format is acquired. A machine learning engine processes the markup using a machine learning model, to identify a markup type, identify markup properties, correlate, the markup to a CAD object needed to update the CAD drawing, and determine, CAD object properties and CAD application properties. The CAD object with the CAD object properties is provided in the CAD application using the CAD application properties. User input is accepted and the CAD drawing is updated based thereon. The machine learning model is updated based on the user input and utilized to process future markups.

Abstract: Carcinomas typically invade as a cohesive multicellular unit, a process termed collective invasion. It remains unclear how different subpopulations of cancer cells contribute to this process. We developed three-dimensional (3D) organoid assays to identify the most invasive cancer cells in primary breast tumors. Collective invasion was led by specialized cancer cells that were defined by their expression of basal epithelial genes, such as cytokeratin-14 (K14) and p63. Furthermore, K14+ cells led collective invasion in the major human breast cancer subtypes. Importantly, lumenal cancer cells were observed to convert phenotypically to invasive leaders following induction of basal epithelial genes. Although only a minority of cells within lumenal tumors expressed basal epithelial genes, knockdown of either K14 or p63 was sufficient to block collective invasion. Our data reveal that heterotypic interactions between epithelial subpopulations are critical to collective invasion.

Abstract: A metal-halogen flow battery system includes an electrolyte composition that includes an aqueous solution including a metal halide, a halogen, a metal plating enhancer and at least one of an anti-dendrite agent, and an anti-corrosion agent.

Abstract: A measurement device for measuring voltages along a linear array of voltage sources, such as a fuel cell stack, includes at least one movable voltage probe that measures voltage transitions along an array element. The measured voltage is used to determine a distance of travel of the at least one voltage probe along the fuel cell stack from the speed of the probe and the timing of the transitions.

Abstract: A system may provide for retrieving data within a selected region of a map is provided. The system may include mobile devices configured to display a map and to receive a user selection of a region of the map. An application server may receive data from the mobile device, representing the user selected region of the map and a search criterion. A database may be in operative communication with the application server and executes a query using the data representing the selected region of the map and the search criterion and to return data results corresponding to a plurality of locations within the selected region and related to the search criterion. The mobile device may further be configured to display the data results corresponding to the plurality of locations on the selected region of the map and the displayed data results are automatically updated when the user moves the selected region of the map.

Abstract: A measurement device for measuring voltages along a linear array of voltage sources, such as a fuel cell stack, includes at least one movable voltage probe that measures voltage transitions along an array element. The measured voltage is used to determine a distance of travel of the at least one voltage probe along the fuel cell stack from the speed of the probe and the timing of the transitions.

Abstract: Carcinomas typically invade as a cohesive multicellular unit, a process termed collective invasion. It remains unclear how different subpopulations of cancer cells contribute to this process. We developed three-dimensional (3D) organoid assays to identify the most invasive cancer cells in primary breast tumors. Collective invasion was led by specialized cancer cells that were defined by their expression of basal epithelial genes, such as cytokeratin-14 (K14) and p63. Furthermore, K14+ cells led collective invasion in the major human breast cancer subtypes. Importantly, lumenal cancer cells were observed to convert phenotypically to invasive leaders following induction of basal epithelial genes. Although only a minority of cells within lumenal tumors expressed basal epithelial genes, knockdown of either K14 or p63 was sufficient to block collective invasion. Our data reveal that heterotypic interactions between epithelial subpopulations are critical to collective invasion.

Abstract: This invention describes a process that allows 3D graphics to be rendered on a 2D capable client system by aggregating the data on the server side through a plurality of machines.