Abstract: A toe guard for use on a wheel assembly may include a first and second sidewall, each sidewall including an opening configured to engage with an axle of the wheel assembly. The first and second sidewalls may each further include one or more notches. The toe guard may further include a first locking pin configured to engage with at least one of the notches of the first and second sidewalls. Additionally, the toe guard may include one or more support plates connecting the first and second sidewalls, and a front plate configured to engage with at least one of the support plates or connect with at least one of the sidewalls.

Abstract: Novel therapeutic protocols are provided relating to the use of an anti-IL-6 antibody, e.g., Clazakizumab, in order to prevent, stabilize, reduce or arrest antibody mediated rejection responses in patients receiving solid organ transplants, e.g., patients receiving transplanted kidney, heart, liver, lungs, pancreas, intestines or combinations of any of the foregoing. Also novel therapeutic protocols are provided pertaining to the use of an anti-IL-6 antibody, e.g., Clazakizumab, as part of a desensitization protocol for treating highly sensitized subjects waiting for and/or after allograft transplants, e.g., patients who are to receive solid organ transplants, e.g., kidney, heart, liver, lungs, pancreas, intestines, skin or combinations of any of the foregoing. The foregoing treatments may be effected in combination with one or more other immunosuppressant regimens or other desensitization procedures.

Abstract: A nestable shopping cart includes an upright frame, an upper angle support and a pair of tie bars extending out from the upright frame. A tray is pivotally connected to the upright frame. The tray includes a utility position and a nested position. The tray includes a tapered front and at least one side. A slope plate is mounted to at least one side of the tray. In the nested position, the nestable shopping cart is nested with another nestable shopping cart, resulting in a nesting gap of about 11 inches between the shopping carts.

Abstract: A steerable delivery system is provided for delivering a replacement heart valve to a native heart valve location. The steerable delivery system includes an outer sheath assembly having a capsule along a distal end portion for retaining the replacement heart valve in a compressed configuration. The capsule is constructed to provide both compression resistance and flexibility. The capsule may be formed with an outer polymer layer, a metal middle layer located on a radially inner surface of the outer polymer layer, and an inner liner located on a radially inner surface of the metal middle layer. A fluoroelastomer layer is provided for bonding the inner liner to the metal middle layer. The metal middle layer is preferably a metal hypotube.

Abstract: A toe guard for use on a wheel assembly may include a first and second sidewall, each sidewall including an opening configured to engage with an axle of the wheel assembly. The first and second sidewalls may each further include one or more notches. The toe guard may further include a first locking pin configured to engage with at least one of the notches of the first and second sidewalls. Additionally, the toe guard may include one or more support plates connecting the first and second sidewalls, and a front plate configured to engage with at least one of the support plates or connect with at least one of the sidewalls.

Abstract: A toe guard for use on a wheel assembly may include a first and second sidewall, each sidewall including an opening configured to engage with an axle of the wheel assembly. The first and second sidewalls may each further include one or more notches. The toe guard may further include a first locking pin configured to engage with at least one of the notches of the first and second sidewalls. Additionally, the toe guard may include one or more support plates connecting the first and second sidewalls, and a front plate configured to engage with at least one of the support plates or connect with at least one of the sidewalls.

Abstract: A nestable shopping cart has an upright frame, and a tray pivotally connected to the upright frame. The tray includes a utility position, a nested position, an inside, and an outside. Further included is a perimeter wire surrounding the tray and a tapered front. The perimeter wire surrounds the outside of the tray until the tapered front, and then the perimeter wire surrounds the inside of the tapered front.

Abstract: The present disclosure relates to uses of an anti-IL-6 antibody, e.g., clazakizumab in order to prevent, stabilize, reduce, or otherwise treat acute or chronic respiratory distress syndrome (ARDS or CRDS) and symptoms thereof such as lung damage, and also to treat cytokine storm syndrome, in patients with or suspected of having a bacterial, viral, or fungal infection, such as a coronavirus infection, e.g., COVID-19, SARS, MERS, or another bacterial or viral infection which may cause acute or chronic respiratory distress syndrome or cytokine storm syndrome.

Abstract: A nestable shopping cart includes an upright frame, an upper angle support and a pair of tie bars extending out from the upright frame. A tray is pivotally connected to the upright frame. The tray includes a utility position and a nested position. The tray includes a tapered front and at least one side. A slope plate is mounted to at least one side of the tray. In the nested position, the nestable shopping cart is nested with another nestable shopping cart, resulting in a nesting gap of about 11 inches between the shopping carts.

Abstract: A nestable shopping cart may include an upright frame, and a tray pivotally connected to the upright frame and comprising a utility position and a nested position. The nestable shopping cart may further include one or more casters configured to be removably attached to the upright frame, the one or more casters comprising a stem comprising a shape directionally aligned with a first opening of the upright frame.

Abstract: A nestable shopping cart includes an upright frame, an upper angle support and a pair of tie bars extending out from the upright frame. A tray is pivotally connected to the upright frame. The tray includes a utility position and a nested position. The tray includes a tapered front and at least one side. A slope plate is mounted to at least one side of the tray. In the nested position, the nestable shopping cart is nested with another nestable shopping cart, resulting in a nesting gap of about 11 inches between the shopping carts.

Abstract: A nestable shopping cart has an upright frame, and a tray pivotally connected to the upright frame. The tray includes a utility position, a nested position, an inside, and an outside. Further included is a perimeter wire surrounding the tray and a tapered front. The perimeter wire surrounds the outside of the tray until the tapered front, and then the perimeter wire surrounds the inside of the tapered front.

Abstract: A nestable shopping cart includes an upright frame, an upper angle support and a pair of tie bars extending out from the upright frame. A tray is pivotally connected to the upright frame. The tray includes a utility position and a nested position. The tray includes a tapered front and at least one side. A slope plate is mounted to at least one side of the tray. In the nested position, the nestable shopping cart is nested with another nestable shopping cart, resulting in a nesting gap of about 11 inches between the shopping carts.

Abstract: Novel therapeutic protocols are provided relating to the use of an anti-IL-6 antibody, e.g., Clazakizumab in order to prevent, stabilize, reduce or arrest antibody mediated rejection responses in patients receiving solid organ transplants, e.g., patients receiving transplanted kidney, heart, liver, lungs, pancreas, intestines or combinations of any of the foregoing. Also novel therapeutic protocols are provided pertaining to the use of an anti-IL-6 antibody, e.g., Clazakizumab as part of a desensitization protocol for treating highly sensitized subjects waiting for and/or after allograft transplants, e.g., patients who are to receive solid organ transplants, e.g., kidney, heart, liver, lungs, pancreas, intestines, skin or combinations of any of the foregoing. The foregoing treatments may be effected in combination with one or more other immunosuppressant regimens or other desensitization procedures.

Abstract: A user of a web application can perform a drag and drop operation from a first component of the web application to a second component of the web application. The drag and drop operation can include three actions. The first action can be initializing a drag of an object within a first component of a web application. The second action can be dragging the object from within the first component over a drop target located within a second component of the web application. The third action can be dropping the object onto the drop target located within the second component of the web application. One of the first and second components can be a web component, and the other component can be a visualization component. The first and second components of the web application can communicate with each other using a communication component of the web application.

Abstract: One embodiment is directed to a computer program, embodied on a computer readable medium. The computer program is configured to control a processor to execute instructions. The instructions include receiving a selection of built-in interactive regions provided by a visualization component, aggregating the selected set of regions, and creating one or more custom regions from the aggregation of the selected set of regions.

Abstract: One embodiment is directed to a computer program, embodied on a computer readable medium. The computer program is configured to control a processor to execute instructions. The instructions include receiving one or more files as input. The files may each include descriptions of different shapes. The instructions may further include interpreting each of the files as a layer of shapes, converting each of the shapes into an interactive element, layering the converted shapes onto one another to create a custom interactive display, and displaying the custom interactive display.