Abstract: Two or more feed materials that possess differing syngas generation potentials are mixed in a mixer and fed as a composite feed stream into a gasifier to produce syngas. By controlling the feed rate of the mixture into the gasifier as well as the feed rates of one or more of the individual feed materials into the mixer, the syngas is produced at a target production rate, with target energy content (BTU). Potential feed materials include, but are not limited to, construction and demolition (C&D) debris, municipal solid waste (MSW), other sewage-related solids, waste tires, and other substances that contain varying levels of organic compounds capable of producing a syngas.

Abstract: Application of a virus with poloxamer alone onto atria results in diffuse epicardial gene transfer with negligible penetration into the myocardium. Progressive increases in protease concentration, however, allow transmural gene transfer. After protease exposure, echocardiographic left atrial diameter does not change. Left atrial ejection fraction decreases on post-operative day 3, but returns to baseline by day 7. At appropriate protease concentrations, tissue tensile strength is unaffected by the procedure. Transmural atrial gene transfer can be effected using this direct “painting” method.

Abstract: The present provides methods and compositions that enable effective delivery of nucleic acids to desired cells, including to a solid organ such as a mammalian heart. The methods and compositions enable effective gene transfer and subsequent expression to a majority of cells throughout a solid organ such as the heart. Methods and compositions of the invention preferably provide enhanced vascular permeability that enables increased gene transfer to targeted cells, but without significant degradation or injury to endothelial cell layers. Global delivery of nucleic acid to an intact heart has been achieved with as little as 2 minutes of intracoronary exposure to the administered nucleic acid.

Abstract: A pressure-sensitive light-extracting drawing surface including a light guide operable to receive a light source, wherein light is extracted from a light guide when pressure is applied to the drawing surface by a marking instrument. A resultant light-emitting drawing can be erased or can be made permanent. An optional multi-layered film disposed on the light guide allows drawings to be created in fluorescent, luminescent, phosphorescent, or photochromic colors. A background sheet containing designs may be inserted behind the light guide. The drawing surface can be embodied as a pressure-sensitive light-extracting “paper.” The invention may be embodied as a drawing tablet, a drawing tablet add-on to a modular graphic display device, or a toy drawing tablet for tracing alphabets, numerals, and characters from comic books, cartoons, and movies.

Abstract: Disclosed are methods of preventing or treating cardiac arrhythmia. In one embodiment, the methods include administering to an amount of at least one polynucleotide that modulates an electrical property of the heart. The methods have a wide variety of important uses including treating cardiac arrhythmia.

Abstract: The present provides methods and compositions that enable effective delivery of nucleic acids to desired cells, including to a solid organ such as a mammalian heart. The methods and compositions enable effective gene transfer and subsequent expression to a majority of cells throughout a solid organ such as the heart. Methods and compositions of the invention preferably provide enhanced vascular permeability that enables increased gene transfer to targeted cells, but without significant degradation or injury to endothelial cell layers.

Abstract: The present provides methods and compositions that enable effective delivery of nucleic acids to desired cells, including to a solid organ such as a mammalian heart. The methods and compositions enable effective gene transfer and subsequent expression to a majority of cells throughout a solid organ such as the heart. Methods and compositions of the invention preferably provide enhanced vascular permeability that enables increased gene transfer to targeted cells, but without significant degradation or injury to endothelial cell layers. Global delivery of nucleic acid to an intact heart has been achieved with as little as 2 minutes of intracoronary exposure to the administered nucleic acid.

Abstract: Application of a virus with poloxamer alone onto atria results in diffuse epicardial gene transfer with negligible penetration into the myocardium. Progressive increases in protease concentration, however, allow transmural gene transfer. After protease exposure, echocardiographic left atrial diameter does not change. Left atrial ejection fraction decreases on post-operative day 3, but returns to baseline by day 7. At appropriate protease concentrations, tissue tensile strength is unaffected by the procedure. Transmural atrial gene transfer can be effected using this direct “painting” method.

Abstract: Disclosed are methods of preventing or treating cardiac arrhythmia. In one embodiment, the methods include administering to an amount of at least one polynucleotide that modulates an electrical property of the heart. The methods have a wide variety of important uses including treating cardiac arrhythmia.

Abstract: Disclosed are methods of preventing or treating cardiac arrhythmia. In one embodiment, the methods include administering to an amount of at least one polynucleotide that modulates an electrical property of the heart. The methods have a wide variety of important uses including treating cardiac arrhythmia.

Abstract: Cabinet modules are readily attached and removed from selected attachment parts on a vertical support to provide customized portable storage and instrument mounting. Drawers may be accommodated within a module. A lock on a single drawer can secure all other drawers and modules on one side of the vertical support. An uninterruptable power supply can e incorporated into an enclosed, ventilated module and located at an attachment point low on the vertical support to maintain a low center of gravity while supplying portable power to electronic instruments carried on the vertical support.

Abstract: Cabinet modules are readily attached and removed from selected attachment parts on a vertical support to provide customized portable storage and instrument mounting. Drawers may be accommodated within a module. A lock on a single drawer can secure all other drawers and modules on one side of the vertical support. An uninterruptable power supply can e incorporated into an enclosed, ventilated module and located at an attachment point low on the vertical support to maintain a low center of gravity while supplying portable power to electronic instruments carried on the vertical support.

Abstract: Disclosed are methods of preventing or treating cardiac arrhythmia. In one embodiment, the methods include administering to an amount of at least one polynucleotide that modulates an electrical property of the heart. The methods have a wide variety of important uses including treating cardiac arrhythmia.

Abstract: Cabinet modules are readily attached and removed from selected attachment parts on a vertical support to provide customized portable storage and instrument mounting. Drawers may be accommodated within a module. A lock on a single drawer can secure all other drawers and modules on one side of the vertical support. An uninterruptable power supply can be incorporated into an enclosed, ventilated module and located at an attachment point low on the vertical support to maintain a low center of gravity while supplying portable power to electronic instruments carried on the vertical support.

Abstract: The present provides methods and compositions that enable effective delivery of nucleic acids to desired cells, including to a solid organ such as a mammalian heart. The methods and compositions enable effective gene transfer and subsequent expression to a majority of cells throughout a solid organ such as the heart. Methods and compositions of the invention preferably provide enhanced vascular permeability that enables increased gene transfer to targeted cells, but without significant degradation or injury to endothelial cell layers. Global delivery of nucleic acid to an intact heart has been achieved with as little as 2 minutes of intracoronary exposure to the administered nucleic acid.

Abstract: The present provides methods and compositions that enable effective delivery of nucleic acids to desired cells, including to a solid organ such as a mammalian heart. The methods and compositions enable effective gene transfer and subsequent expression to a majority of cells throughout a solid organ such as the heart. Methods and compositions of the invention preferably provide enhanced vascular permeability that enables increased gene transfer to targeted cells, but without significant degradation or injury to endothelial cell layers.

Abstract: The present provides methods and compositions that enable effective delivery of nucleic acids to desired cells, including to a solid organ such as a mammalian heart. The methods and compositions enable effective gene transfer and subsequent expression to a majority of cells throughout a solid organ such as the heart. Methods and compositions of the invention preferably provide enhanced vascular permeability that enables increased gene transfer to targeted cells, but without significant degradation or injury to endothelial cell layers. Global delivery of nucleic acid to an intact heart has been achieved with as little as 2 minutes of intracoronary exposure to the administered nucleic acid.