Abstract: A method of separating a fluid includes adding a fluid to a canister of a fluid separator. The canister includes first and second barriers disposed concentrically within the canister that define a first and second annulus within the canister, and a canister rotor having a first magnet associated therewith. The method includes rotating an induction base rotor disposed within an induction base. The induction base rotor includes a second magnet. The canister rotor and the induction base rotor are magnetically coupled and rotating the induction base rotor causes the canister rotor to rotate. The method further includes forming a vortex in the fluid via the rotation of the canister rotor, and the vortex causes the fluid to separate into a first component and a second component.

Abstract: A method of separating a fluid includes adding a fluid to a canister of a fluid separator. The canister includes first and second barriers disposed concentrically within the canister that define a first and second annulus within the canister, and a canister rotor having a first magnet associated therewith. The method includes rotating an induction base rotor disposed within an induction base. The induction base rotor includes a second magnet. The canister rotor and the induction base rotor are magnetically coupled and rotating the induction base rotor causes the canister rotor to rotate. The method further includes forming a vortex in the fluid via the rotation of the canister rotor, and the vortex causes the fluid to separate into a first component and a second component.

Abstract: The invention is directed to a bone void filler comprising a scaffold or matrix. The scaffold or matrix may include a porous inorganic matrix component and/or a 3D-printed implantable device. The bone void filler may include a cellular component containing cells, some of which are capable of making extracellular matrix resembling native bone tissue. The bone void filler may include an organic matrix, such as, an organic biopolymer that aids in cell retention and renders the scaffold or matrix moldable. The bone void filler may include growth factors and/or cytokines. The bone void filler may include a clotting agent.

Abstract: The invention is directed to a bone void filler comprising a scaffold or matrix. The scaffold or matrix may include a porous inorganic matrix component. The bone void filler may include a cellular component containing cells, some of which are capable of making extracellular matrix resembling native bone tissue. The bone void filler may include an organic matrix, such as, an organic biopolymer that aids in cell retention and renders the scaffold or matrix moldable. The bone void filler may include growth factors and/or cytokines. The bone void filler may include a clotting agent.

Abstract: The invention is directed to an interbody fusion device comprises a fusion bearing device and a retention device and further comprises two bone screws that pass through the retention device and into the vertebral bodies. When implanted, the construct is flush with the anterior face of the vertebras and provides support and temporary fixation for the ultimate fusion of the vertebral bodies.

Abstract: The invention is directed to an interbody fusion device comprises a load bearing component and a retention component and further comprises two bone screws that pass through the retention device and into the vertebral bodies. When implanted, the construct is flush with the anterior face of the vertebras and provides support and temporary fixation for the ultimate fusion of the vertebral bodies.

Abstract: A method and apparatus is provided for use in spinal fusion procedures. An interbody fusion device has a first piece that is a load bearing device designed to bear the axial loading from the end plates of adjacent vertebrae. A second piece of the interbody fusion device is a retention device whose function is to prevent migration of the load bearing device. One or more fasteners secure the retention device to the vertebrae above and below the load bearing device. The fasteners cause the end plates of the vertebrae to compress the end plates to the load bearing device to facilitate proper fusion. The second piece can be configured to include lips that abut the apothyseal rings during, with the plate including bores angled such that fasteners penetrate the apothyseal rings.

Abstract: The claimed invention is directed to a spinal fusion device comprising a load-bearing interbody component configured to fit between two adjacent vertebrae, wherein the interbody component comprises one or more openings to allow access to the vertebrae, a retention component that is configured to at least partially close the one or more openings of the interbody component and one or more fasteners that are coupled to the retention component to compress the two adjacent vertebrae to the interbody component, and methods of using a spinal fusion device.

Abstract: Embodiments of the invention is directed to methods of forming a bone-like material, by placing a matrix into a culture container, adding cells to the matrix, placing the tissue-cell construct into the culturing environment and incubating the construct under appropriate conditions for the time required to produce an amount of bone-like material of sufficient volume to be harvested for further processing. Other embodiments of the invention are directed to the use of the bone-like material formed by methods of the invention in implantation procedures.

Abstract: The invention comprises a combination of biological elements that will naturally remodel in vivo based on applied mechanical forces. The final composition will possess mechanical properties similar to cartilage or a disc, and significantly less stiff than bone or implants comprised of metals or plastics. The equilibrium stress conduction will minimize unnatural forces on neighboring healthy discs.

Abstract: The invention is directed to a work station for use in performing processing of patient samples, storing equipment and drugs in a hospital and the like, the cart having a lower housing having caster wheels mounted on the bottom thereof, the lower housing having angular-shaped side panels therearound which may be opened for entrance into all sides of the housing, and one or more of the side panels; an upper housing mounted on top of the lower housing, the upper housing having one or more side panels therearound; and one or more work areas mounted on top of the upper housing, the shelf adapted for receiving point-of-care equipment.

Abstract: The invention features an implant assembly for stabilization of a facet joint including an implant having a U-shaped body. The U-shaped body has a rounded front end, an open back end, first and second elongated components extending from the rounded front end, forming the U-shaped body and ending at the open back end and a helical structure extending within the U-shaped body that serves as a locking mechanism.

Abstract: The invention is directed to a bone void filler comprising a scaffold or matrix. The scaffold or matrix may include a porous inorganic matrix component and/or a 3D-printed implantable device. The bone void filler may include a cellular component containing cells, some of which are capable of making extracellular matrix resembling native bone tissue. The bone void filler may include an organic matrix, such as, an organic biopolymer that aids in cell retention and renders the scaffold or matrix moldable. The bone void filler may include growth factors and/or cytokines. The bone void filler may include a clotting agent.

Abstract: The invention is directed to a therapeutic composition that includes a first cell preparation that includes isolated stromal cells of a first type and a second cell preparation that includes isolated stromal cells of a second type. The first and second cell preparations may include cultured cells. The stromal cells may include adipose stromal cells and bone marrow derived stromal cells. The therapeutic composition may include a blood component that includes one or more of platelet-poor plasma, concentrated platelet-poor plasma, platelet-rich plasma, and whole blood.

Abstract: The invention is directed to a method for isolating stromal cells to form a therapeutic composition; and administering said therapeutic composition to the subject. A further embodiment of the invention is directed to therapeutic compositions comprising isolated stromal cells.

Abstract: The invention is directed to a bone void filler comprising a scaffold or matrix. The scaffold or matrix may include a porous inorganic matrix component. The bone void filler may include a cellular component containing cells, some of which are capable of making extracellular matrix resembling native bone tissue. The bone void filler may include an organic matrix, such as, an organic biopolymer that aids in cell retention and renders the scaffold or matrix moldable. The bone void filler may include growth factors and/or cytokines. The bone void filler may include a clotting agent.

Abstract: A method and apparatus is provided for use in spinal fusion procedures. An exemplary interbody fusion device includes a synthetic non-metallic radiolucent interbody spacer having an opening formed between its top and bottom surfaces. A cancellous allograft plug is configured to be disposed within the opening formed in the spacer. The cancellous allograft plug can be reconstituted with a material that will help to facilitate fusion of the vertebrae.

Abstract: The invention is directed to an interbody fusion device comprises a load bearing component and a retention component and further comprises two bone screws that pass through the retention device and into the vertebral bodies. When implanted, the construct is flush with the anterior face of the vertebras and provides support and temporary fixation for the ultimate fusion of the vertebral bodies.

Abstract: The invention is directed to an anchor for fixing a tendon or a ligament in a bone comprising: an elongated tubular body having a bore extending along a longitudinal axis, said tubular body comprising first and second independent parts slidably contacting each other, the first and second independent parts each having an outer circumferential surface along a length thereof parallel to the longitudinal axis, and each having an elongated partial inner bore, such that the tubular body is capable of mounting a tendon or ligament within the partial inner bore.

Abstract: The invention is directed to a spinal fusion device, comprising a load bearing component and an anterior component, wherein the load bearing component and the anterior component are configured to mate together by complimentary coupling members, and further comprising an external outer plate configured to span two vertebrae, wherein the outer plate includes bores configured to receive bone screws for coupling to vertebrae.